Chloé E. Hill
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View article: Challenges in antiseizure medication discontinuation decisions: A qualitative study of clinicians who see patients with epilepsy
Challenges in antiseizure medication discontinuation decisions: A qualitative study of clinicians who see patients with epilepsy Open
Many challenges remain in ASM discontinuation decisions after a period of seizure-freedom. Our results encourage future efforts to improve individualized seizure risk prediction and to develop prediction models into seizure risk calculator…
View article: Antiseizure medication discontinuation: A mixed-methods exploration of factors considered by patients when approaching decision-making
Antiseizure medication discontinuation: A mixed-methods exploration of factors considered by patients when approaching decision-making Open
Numerous themes emerged including reasons favoring continued ASMs (e.g., fear of seizures and their psychosocial consequences, perceiving little downside to continued ASMs) but also many reasons against continued ASMs (e.g., side effects, …
View article: Facilitators and barriers to neurologist referral of patients for epilepsy surgery evaluation
Facilitators and barriers to neurologist referral of patients for epilepsy surgery evaluation Open
Objective Epilepsy surgery offers a potential cure for drug‐resistant epilepsy (DRE), yet surgery is underutilized. An estimated 5% of patients with DRE undergo long‐term EEG monitoring (LTM) annually, the requisite first step of evaluatio…
View article: Effects of alkalinity and carbon in submarine groundwater discharge on coastal acidification in the Baltic Sea
Effects of alkalinity and carbon in submarine groundwater discharge on coastal acidification in the Baltic Sea Open
With increasing atmospheric concentration of carbon dioxide, more CO2 is dissolved in seawater, resulting in ocean acidification (OA). The consequences of OA can be altered by alkalinity (TA), dissolved inorganic carbon (DIC) and freshwate…
View article: 3-Dimension Epithelial Segmentation in Optical Coherence Tomography of the Oral Cavity Using Deep Learning
3-Dimension Epithelial Segmentation in Optical Coherence Tomography of the Oral Cavity Using Deep Learning Open
Purpose: To simplify the application of optical coherence tomography (OCT) for examination of subsurface morphology in the oral cavity and reduce barriers towards adoption of OCT as a biopsy guidance device. The aim of this work was to dev…
View article: Burden of Neurologic Health Care and Incident Neurologic Diagnoses in the Year After COVID-19 or Influenza Hospitalization
Burden of Neurologic Health Care and Incident Neurologic Diagnoses in the Year After COVID-19 or Influenza Hospitalization Open
Compared with a matched cohort of adults with a hospitalization or emergency department visit for influenza infection, those with COVID-19 had significantly fewer health care encounters for 6 major neurologic diagnoses over a year of follo…
View article: Disparities in seizure outcomes revealed by large language models
Disparities in seizure outcomes revealed by large language models Open
Objective Large-language models (LLMs) can potentially revolutionize health care delivery and research, but risk propagating existing biases or introducing new ones. In epilepsy, social determinants of health are associated with disparitie…
View article: GC Insights: Fostering transformative change for biodiversity restoration through transdisciplinary research
GC Insights: Fostering transformative change for biodiversity restoration through transdisciplinary research Open
According to a 2019 United Nations report, of all the known species, up to 1 million face extinction globally. Despite being considered a pressing global risk with several international efforts to protect and to restore, biodiversity loss …
View article: Reply on RC2
Reply on RC2 Open
Abstract. Despite being considered one of the most pressing global issues, biodiversity loss and the degradation of ecosystems is continuing at an alarming rate. In December 2022, COP15 saw the adoption of the Kunming-Montreal Global Biodi…
View article: Reply on RC1
Reply on RC1 Open
Abstract. Despite being considered one of the most pressing global issues, biodiversity loss and the degradation of ecosystems is continuing at an alarming rate. In December 2022, COP15 saw the adoption of the Kunming-Montreal Global Biodi…
View article: Disparities in seizure outcomes revealed by large language models
Disparities in seizure outcomes revealed by large language models Open
Objective Large-language models (LLMs) in healthcare have the potential to propagate existing biases or introduce new ones. For people with epilepsy, social determinants of health are associated with disparities in access to care, but thei…
View article: Patient Travel Distance to Neurologist Visits
Patient Travel Distance to Neurologist Visits Open
We found that nearly 1 in 5 Medicare beneficiaries who saw a neurologist traveled ≥50 miles 1-way for care, and travel burden was most common for lower-prevalence neurologic conditions that required coordinated multidisciplinary care. Impo…
View article: Comment on egusphere-2023-1730
Comment on egusphere-2023-1730 Open
Abstract. Despite being considered one of the most pressing global issues, biodiversity loss and the degradation of ecosystems is continuing at an alarming rate. In December 2022, COP15 saw the adoption of the Kunming-Montreal Global Biodi…
View article: GC Insights: Fostering transformative change for biodiversity restoration through transdisciplinary research
GC Insights: Fostering transformative change for biodiversity restoration through transdisciplinary research Open
Despite being considered one of the most pressing global issues, biodiversity loss and the degradation of ecosystems is continuing at an alarming rate. In December 2022, COP15 saw the adoption of the Kunming-Montreal Global Biodiversity Fr…
View article: Predictors of referral for long‐term <scp>EEG</scp> monitoring for Medicare beneficiaries with drug‐resistant epilepsy
Predictors of referral for long‐term <span>EEG</span> monitoring for Medicare beneficiaries with drug‐resistant epilepsy Open
Objective For people with drug‐resistant epilepsy, the use of epilepsy surgery is low despite favorable odds of seizure freedom. To better understand surgery utilization, we explored factors associated with inpatient long‐term EEG monitori…
View article: Generalization of finetuned transformer language models to new clinical contexts
Generalization of finetuned transformer language models to new clinical contexts Open
Objective We have previously developed a natural language processing pipeline using clinical notes written by epilepsy specialists to extract seizure freedom, seizure frequency text, and date of last seizure text for patients with epilepsy…
View article: Characterizing the treatment gap in the United States among adult patients with a new diagnosis of epilepsy
Characterizing the treatment gap in the United States among adult patients with a new diagnosis of epilepsy Open
Objective Epilepsy is largely a treatable condition with antiseizure medication (ASM). Recent national administrative claims data suggest one third of newly diagnosed adult epilepsy patients remain untreated 3 years after diagnosis. We aim…
View article: Long‐term epilepsy outcome dynamics revealed by natural language processing of clinic notes
Long‐term epilepsy outcome dynamics revealed by natural language processing of clinic notes Open
Objective Electronic medical records allow for retrospective clinical research with large patient cohorts. However, epilepsy outcomes are often contained in free text notes that are difficult to mine. We recently developed and validated no…
View article: Belonging: A Phenomenological Study of Systemic Racism Experienced Among Black Students in Occupational Therapy Programs
Belonging: A Phenomenological Study of Systemic Racism Experienced Among Black Students in Occupational Therapy Programs Open
Belonging, a crucial aspect of humanity and justice, is negated by racism. Formal analyses have shown that racial and ethnic minorities experience significantly higher rates of racial discrimination, with the greatest disparity being among…
View article: Costs and Utilization of New-to-Market Neurologic Medications
Costs and Utilization of New-to-Market Neurologic Medications Open
Despite the increasing number of FDA-approved neurologic medications, utilization of newly approved medications in the privately insured population remains small. Given the high costs and similar efficacy for most of the new medications, l…
View article: Learning from the COVID-19 Pandemic Crisis to Overcome the Global Environmental Crisis
Learning from the COVID-19 Pandemic Crisis to Overcome the Global Environmental Crisis Open
The COVID-19 crisis and the environmental crisis share a range of similarities. Both crises take place on a global scale and affect all aspects of our lives. However, we humans respond differently to these challenges. Here, we compare and …
View article: Segmentation and Risk Score Prediction of Head and Neck Cancers in PET/CT Volumes with 3D U-Net and Cox Proportional Hazard Neural Networks
Segmentation and Risk Score Prediction of Head and Neck Cancers in PET/CT Volumes with 3D U-Net and Cox Proportional Hazard Neural Networks Open
We utilized a 3D nnU-Net model with residual layers supplemented by squeeze and excitation (SE) normalization for tumor segmentation from PET/CT images provided by the Head and Neck Tumor segmentation chal-lenge (HECKTOR). Our proposed los…
View article: Polypharmacy composition and patient- and provider-related variation in patients with epilepsy
Polypharmacy composition and patient- and provider-related variation in patients with epilepsy Open
Patients with epilepsy fill a large number of medications from a large number of providers, including high-risk medications. Variation in medication fills was substantially more related to provider-to-provider rather than patient-to-patien…
View article: Definitions of Drug-Resistant Epilepsy for Administrative Claims Data Research
Definitions of Drug-Resistant Epilepsy for Administrative Claims Data Research Open
BACKGROUND AND OBJECTIVE: To assess the accuracy of definitions of drug-resistant epilepsy applied to administrative claims data. METHODS: We randomly sampled 450 patients from a tertiary health system with ≥1 epilepsy/convulsion encounter…
View article: Efficacy of Home Anticonvulsant Administration for Second-Line Status Epilepticus Treatment
Efficacy of Home Anticonvulsant Administration for Second-Line Status Epilepticus Treatment Open
This study provides Class II evidence that for patients with refractory convulsive status epilepticus, use of a home second-line anticonvulsant compared to a nonhome anticonvulsant did not significantly affect the probability of stopping s…
View article: How to vEGU: networking
How to vEGU: networking Open
<p>This year vEGU21 has flexible networking tools available to conveners and attendees, allowing people to engage and socialise with, and learn from one another in almost any way they wish. Networking is facilitated by three key tool…