Yang Zi
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View article: Rumen Microbial Diversity and Metabolome Analysis Reveals the Effects of Alkaline Metal Ion Complexes on Muscle Quality of Lambs
Rumen Microbial Diversity and Metabolome Analysis Reveals the Effects of Alkaline Metal Ion Complexes on Muscle Quality of Lambs Open
This study investigated the effects of dietary supplementation with an alkaline metal ion complex (AMIC) on growth performance, meat quality, rumen microbiota, and metabolome in Hu lambs. Fifty lambs were randomly assigned to either a cont…
View article: Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase
Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase Open
Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis. The precise targeting and sophisticated modulation of redox process…
View article: Tunable Photoluminescent and Photothermal Properties of Organic Cocrystals Containing Hydrogen‐Bonded Interlocked Planar Molecules
Tunable Photoluminescent and Photothermal Properties of Organic Cocrystals Containing Hydrogen‐Bonded Interlocked Planar Molecules Open
Expanding the structural diversity of precursor molecules can inject greater vitality into the development of cocrystal engineering. Here, two hydrogen‐bond interlocked planar molecules, HNAO and HPAO is reported, which coassemble with 1,2…
View article: Computed Tomography (CT)-Guided Medical Sodium Hyaluronate Gel for Paravascular Microwave Ablation of Rabbit Liver Large Vessels
Computed Tomography (CT)-Guided Medical Sodium Hyaluronate Gel for Paravascular Microwave Ablation of Rabbit Liver Large Vessels Open
Objective The objective of this study is to investigate the effect of medical sodium hyaluronate gel on large blood vessels during microwave ablation (MWA) of rabbit hepatic paravalves. Methods Forty-eight New Zealand large white rabbits w…
View article: Research Progress on Rosacea and Cutaneous Co-Morbidities and Systemic Diseases
Research Progress on Rosacea and Cutaneous Co-Morbidities and Systemic Diseases Open
Rosacea can be associated with a variety of cutaneous co-morbidities. In addition to skin lesions, rosacea is associated with systemic diseases such as cardiovascular and metabolic diseases, respiratory diseases, gastrointestinal diseases …
View article: Development and Mode Innovation of Cultural Tourism Resource based on Industrial Integration
Development and Mode Innovation of Cultural Tourism Resource based on Industrial Integration Open
The cultural tourism industry contributes to the growth of both cultural and tourism industries. Cultural Tourism Resource (CTR) is the prerequisite for the integrated development of the cultural tourism industry. Developing potential CTR …
View article: Machine learning guided prediction of warfarin blood levels for personalized medicine based on clinical longitudinal data from cardiac surgery patients: a prospective observational study
Machine learning guided prediction of warfarin blood levels for personalized medicine based on clinical longitudinal data from cardiac surgery patients: a prospective observational study Open
Background: Warfarin is a common oral anticoagulant, and its effects vary widely among individuals. Numerous dose-prediction algorithms have been reported based on cross-sectional data generated via multiple linear regression or machine le…
View article: Elucidating immune-related gene transcriptional programs via factorization of large-scale RNA-profiles
Elucidating immune-related gene transcriptional programs via factorization of large-scale RNA-profiles Open
Summary Recent developments in immunotherapy, including immune checkpoint blockade (ICB) and adoptive cell therapy, have encountered challenges such as immune-related adverse events and resistance, especially in solid tumors. To advance th…
View article: Liquid crystal monomers disrupt photoreceptor patterning of zebrafish larvae via thyroid hormone signaling
Liquid crystal monomers disrupt photoreceptor patterning of zebrafish larvae via thyroid hormone signaling Open
Liquid crystal monomers (LCMs) are the raw material for liquid crystal displays, and their use is steadily increasing in electronic products. Recently, LCMs have been reported to be novel endocrine disrupting chemicals, however, the mechan…
View article: Depletion of effector regulatory T cells drives major response to induction dual immune checkpoint blockade
Depletion of effector regulatory T cells drives major response to induction dual immune checkpoint blockade Open
In a phase 2 trial, local-regionally advanced HPV-positive oropharyngeal carcinoma (OPC) patients received ipilimumab (anti-CTLA-4) and nivolumab (anti-PD-1) as induction immunotherapy and concurrently with radiotherapy ( NCT03799445 ). Co…
View article: Genetically engineered cell-derived nanovesicles for cancer immunotherapy
Genetically engineered cell-derived nanovesicles for cancer immunotherapy Open
The emergence of genetically engineered extracellular vesicles has marked a new epoch in cancer immunotherapy, presenting substantial clinical potentials.
View article: Towards Faithful Explanations for Text Classification with Robustness Improvement and Explanation Guided Training
Towards Faithful Explanations for Text Classification with Robustness Improvement and Explanation Guided Training Open
Feature attribution methods highlight the important input tokens as explanations to model predictions, which have been widely applied to deep neural networks towards trustworthy AI. However, recent works show that explanations provided by …
View article: 1289 Immune hallmarks construction via non-negative matrix factorization with data-driven functional validations and translational implications
1289 Immune hallmarks construction via non-negative matrix factorization with data-driven functional validations and translational implications Open
Background The need for a concise and objective immune-specific gene set database is crucial in the era of immune checkpoint blockade (ICB) and adoptive cell cancer (ACT) treatments. It is essential for immunologists to understand treatmen…
View article: A Novel Allocation Strategy Based on the Model Predictive Control of Primary Frequency Regulation Power for Multiple Distributed Energy Storage Aggregators
A Novel Allocation Strategy Based on the Model Predictive Control of Primary Frequency Regulation Power for Multiple Distributed Energy Storage Aggregators Open
As the amount of distributed energy storage (DES) in a power system continues to increase, it will not be long before there are multiple DES aggregators participating in frequency regulation, and the realization of their coordinated contro…
View article: Oxidative damage and exocrine dysfunction of ovine fetal pancreas are induced by maternal nutritional restriction
Oxidative damage and exocrine dysfunction of ovine fetal pancreas are induced by maternal nutritional restriction Open
This study investigated oxidative damage and exocrine dysfunction of fetal pancreas caused by maternal nutritional restriction. Eighteen ewes carrying singleton fetus were randomly divided into control group (CG, ad libitum, 0.67 MJ ME/BW0…
View article: Oxidative damage and exocrine dysfunction of ovine fetal pancreas are induced by maternal nutritional restriction
Oxidative damage and exocrine dysfunction of ovine fetal pancreas are induced by maternal nutritional restriction Open
This study investigated oxidative damage and exocrine dysfunction of fetal pancreas caused by maternal nutritional restriction. Eighteen ewes carrying singleton fetus were randomly divided into control group (CG, ad libitum, 0.67 MJ ME/BW0…
View article: Towards Faithful Explanations for Text Classification with Robustness Improvement and Explanation Guided Training
Towards Faithful Explanations for Text Classification with Robustness Improvement and Explanation Guided Training Open
Feature attribution methods highlight the important input tokens as explanations to model predictions, which have been widely applied to deep neural networks towards trustworthy AI. However, recent works show that explanations provided by …
View article: Effects of intrauterine growth restriction during late pregnancy on the cell growth, proliferation, and differentiation in ovine fetal thymuses
Effects of intrauterine growth restriction during late pregnancy on the cell growth, proliferation, and differentiation in ovine fetal thymuses Open
Objective: This study investigated the effects of intrauterine growth restriction (IUGR) during late pregnancy on the cell growth, proliferation, and differentiation in ovine fetal thymuses.Methods: Eighteen time-mated Mongolian ewes with …
View article: Effects of maternal undernutrition during late pregnancy on the regulatory factors involved in growth and development in ovine fetal perirenal brown adipose tissue
Effects of maternal undernutrition during late pregnancy on the regulatory factors involved in growth and development in ovine fetal perirenal brown adipose tissue Open
Objective: The experiment was conducted to evaluate the effects of maternal undernutrition during late pregnancy on the expressions of genes involved in growth and development in ovine fetal perirenal brown adipose tissue (BAT).Methods: Ei…
View article: Morbidity and maternal and infant outcomes of hypertensive disorder in pregnancy in China in 2018
Morbidity and maternal and infant outcomes of hypertensive disorder in pregnancy in China in 2018 Open
Hypertensive disorder in pregnancy is a disease that occurs during pregnancy. We aimed to analyze the morbidity and maternal and infant outcomes with respect to the hypertensive disorder in pregnancy in China in 2018. Clinical data of 38 5…