Chloe J. Walker
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View article: A real‐world survey of the diagnostic journey, current treatment, and burden of mild cognitive impairment or dementia due to Alzheimer's disease in China
A real‐world survey of the diagnostic journey, current treatment, and burden of mild cognitive impairment or dementia due to Alzheimer's disease in China Open
Background We aimed to describe the diagnostic journey, current treatment, caregiving needs, and burden of patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) dementia in China. Method Data were drawn from the Adelph…
View article: Understanding the clinical care pathway of patients with mild cognitive impairment due to Alzheimer's disease and dementia due to Alzheimer's disease: Results from a global real‐world survey
Understanding the clinical care pathway of patients with mild cognitive impairment due to Alzheimer's disease and dementia due to Alzheimer's disease: Results from a global real‐world survey Open
Background With the emergence of disease modifying treatments, the importance of early diagnosis of mild cognitive impairment (MCI) and mild dementia due to Alzheimer's disease (AD) has increased. This research explores the global clinical…
View article: Understanding the burden experienced by patients with mild cognitive impairment due to Alzheimer's disease and dementia due to Alzheimer's disease at different stages of disease severity in a real‐world setting
Understanding the burden experienced by patients with mild cognitive impairment due to Alzheimer's disease and dementia due to Alzheimer's disease at different stages of disease severity in a real‐world setting Open
Background People with Alzheimer's Disease (AD) inevitably progress from preclinical stage, to experiencing mild cognitive impairment (MCI) to dementia. Our aim was to characterise the burden experienced by patients, delineated by disease …
View article: Assessing healthcare resource utilization burden and unmet treatment needs in patients with Parkinson’s disease: results from a real-world study
Assessing healthcare resource utilization burden and unmet treatment needs in patients with Parkinson’s disease: results from a real-world study Open
Aim: Current Parkinson’s disease (PD) research evaluates patients with early and severe PD, but often overlooks patients with intermediate PD. This study aims to quantify unmet treatment needs, disease burden and healthcare resource utiliz…
View article: Real-world diagnosis and management of mild cognitive impairment and Alzheimer's disease dementia in the United Kingdom
Real-world diagnosis and management of mild cognitive impairment and Alzheimer's disease dementia in the United Kingdom Open
Background Timely diagnosis of Alzheimer's disease (AD) remains challenging in the United Kingdom and improvements are needed with the introduction of new therapies. Objective To examine the United Kingdom diagnostic and current treatment …
View article: Treatment landscape and caregiver status for Alzheimer’s disease patients in Canada by disease severity: results from a real‐world survey
Treatment landscape and caregiver status for Alzheimer’s disease patients in Canada by disease severity: results from a real‐world survey Open
Background Caregiver burden associated with Alzheimer’s disease (AD) increases with AD severity, and current treatment options are limited. We aimed to describe the caregiver and treatment landscapes for patients with AD in Canada, split b…
View article: Diagnostic journey and barriers to diagnosis for patients with mild cognitive impairment or dementia due to Alzheimer’s disease in Canada: results from a real‐world survey
Diagnostic journey and barriers to diagnosis for patients with mild cognitive impairment or dementia due to Alzheimer’s disease in Canada: results from a real‐world survey Open
Background Alzheimer’s disease (AD) dementia progresses from preclinical brain changes, through mild cognitive impairment (MCI), to AD with dementia. Early diagnosis and confirmation of underlying AD pathology is crucial; however, there is…
View article: Successful Tralokinumab Treatment for Hand and Foot Atopic Dermatitis in a Patient with Skin of Color: A Case Report
Successful Tralokinumab Treatment for Hand and Foot Atopic Dermatitis in a Patient with Skin of Color: A Case Report Open
Atopic dermatitis (AD) is a common chronic inflammatory skin condition that disproportionately affects skin of color patients. New targeted biological therapies such as tralokinumab are available for the management of AD, but real-world ev…
View article: Opioids for Osteoarthritis: Cross-Sectional Survey of Patient Perspectives and Satisfaction
Opioids for Osteoarthritis: Cross-Sectional Survey of Patient Perspectives and Satisfaction Open
Patients often take opioids to relieve osteoarthritis (OA) pain despite limited benefits and potential harms. This study aimed to compare cross-sectional perspectives of patients that were taking prescription opioid (N = 471) or nonopioid …
View article: Real-World Analysis of Clinical Characteristics, Treatment Patterns, and Patient-Reported Outcomes of Insufficient Responders and Responders to Prescribed Acute Migraine Treatment in China
Real-World Analysis of Clinical Characteristics, Treatment Patterns, and Patient-Reported Outcomes of Insufficient Responders and Responders to Prescribed Acute Migraine Treatment in China Open
Many patients with migraine in China are insufficient responders to AT, experiencing worse symptoms that lead to overall poorer quality of life than responders. This unmet need suggests that new effective treatment options are required for…
View article: COVID-19 vaccination among patients with cicatricial alopecia: patient concerns, experiences, and treatment modifications
COVID-19 vaccination among patients with cicatricial alopecia: patient concerns, experiences, and treatment modifications Open
What is known about this subject in regard to women and their families? Cicatricial (scarring) alopecias, including lichen planopilaris, frontal fibrosing alopecia, and central centrifugal cicatricial alopecia, most commonly affect women. …
View article: Opioid Prescribing for Osteoarthritis: Cross-Sectional Survey among Primary Care Physicians, Rheumatologists, and Orthopaedic Surgeons
Opioid Prescribing for Osteoarthritis: Cross-Sectional Survey among Primary Care Physicians, Rheumatologists, and Orthopaedic Surgeons Open
Opioids are often prescribed for osteoarthritis (OA) pain, despite recommendations to limit use due to minimal benefits and associated harms. This study aimed to assess physicians’ practice patterns and perceptions regarding opioids by spe…
View article: A multicenter descriptive analysis of 270 men with frontal fibrosing alopecia and lichen planopilaris in the United States
A multicenter descriptive analysis of 270 men with frontal fibrosing alopecia and lichen planopilaris in the United States Open
To the Editor: Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are forms of primary lymphocytic cicatricial alopecia characterized by inflammation and fibrosis of the follicular unit causing irreversible hair loss if untreat…
View article: Factors associated with physician-reported treatment status of patients with osteoarthritis pain
Factors associated with physician-reported treatment status of patients with osteoarthritis pain Open
Background Osteoarthritis (OA) is typically associated with pain, but many patients are not treated. Methods This point in time study explored factors associated with treatment status, using logistic regression of data from the Adelphi OA …
View article: Predictors of QOL in Patients with Alopecia Areata
Predictors of QOL in Patients with Alopecia Areata Open
Although alopecia areata (AA) severity is often defined by the degree of scalp hair loss, its impact on QOL can also be a defining measure of severity. In this cross-sectional study (AA Disease Specific Program), 259 patients were surveyed…
View article: Point-in-time survey of healthcare resource utilization, employment, quality of life and caregiver status by disease severity in patients with schizophrenia in the US
Point-in-time survey of healthcare resource utilization, employment, quality of life and caregiver status by disease severity in patients with schizophrenia in the US Open
Greater severity of schizophrenia was associated with a significantly greater number of hospitalizations and greater unemployment due to disability. Compared with mild schizophrenia, severe schizophrenia was associated with worse patient Q…
View article: Body Hair and Identity in Transgender Men: A Cross-Sectional Survey
Body Hair and Identity in Transgender Men: A Cross-Sectional Survey Open
Transgender and gender diverse people can experience increased depression, anxiety, suicidal ideation, and suicide from gender dysphoria (GD). GD occurs due to a discrepancy between a person’s gender identity, assigned gender, and physical…
View article: Subcutaneous metastasis from an atypical pulmonary carcinoid tumor
Subcutaneous metastasis from an atypical pulmonary carcinoid tumor Open
Pulmonary carcinoid tumors are uncommon neuroendocrine tumors that rarely metastasize to the skin. We report the case of a 71-year-old woman with a longstanding history of primary atypical pulmonary carcinoid tumor who presented with a new…
View article: Immunosuppressive therapies for alopecia areata during COVID‐19: A cross‐sectional survey study
Immunosuppressive therapies for alopecia areata during COVID‐19: A cross‐sectional survey study Open
The data that support the findings of this study are available from the corresponding author upon reasonable request.
View article: Hair Growth in a Patient with Alopecia Areata on Tocilizumab
Hair Growth in a Patient with Alopecia Areata on Tocilizumab Open
Introduction: Tocilizumab (TCZ), a recombinant humanized antihuman monoclonal antibody targeting interleukin-6 (IL-6) signaling, is often utilized in the management of autoimmune disease. Few reports have demonstrated hair growth changes i…
View article: Primary Alopecia Neoplastica: A Novel Case Report and Literature Review
Primary Alopecia Neoplastica: A Novel Case Report and Literature Review Open
Alopecia neoplastica (AN) is caused by neoplastic cells damaging hair follicles, resulting in patchy hair loss like cicatricial alopecia and alopecia areata. AN has predominantly described cutaneous metastasis to the scalp from primary vis…