Chloé Magnan
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View article: A narrative review of coagulase-negative staphylococci in diabetic foot infections
A narrative review of coagulase-negative staphylococci in diabetic foot infections Open
SUMMARY Coagulase-negative staphylococci (CoNS) are a group of bacteria commonly found on human skin and mucous membranes. Traditionally regarded as low-virulence microorganisms, they have gained recognition as significant pathogens in hea…
View article: Phage therapy: a promising approach for <i>Staphylococcus aureus</i> diabetic foot infections
Phage therapy: a promising approach for <i>Staphylococcus aureus</i> diabetic foot infections Open
Diabetic foot infections (DFIs), predominantly caused by Staphylococcus aureus , pose a significant healthcare challenge with severe consequences, including amputation. Phage therapy, which utilizes bacteriophages to specifically target ba…
View article: Deciphering pathogenicity and virulence of the first Staphylococcus debuckii isolate from diabetic foot osteomyelitis
Deciphering pathogenicity and virulence of the first Staphylococcus debuckii isolate from diabetic foot osteomyelitis Open
Introduction This study identifies Staphylococcus debuckii as a new coagulase-negative staphylococcal species isolated from diabetic foot osteomyelitis (DFOM) and provides an in-depth analysis of its pathogenic and virulence profile, as we…
View article: TROJAN-MDR: In vitro activity of cefiderocol and comparators against multidrug-resistant Enterobacterales and Pseudomonas aeruginosa strains in Southern France, evaluation of available testing methods performances
TROJAN-MDR: In vitro activity of cefiderocol and comparators against multidrug-resistant Enterobacterales and Pseudomonas aeruginosa strains in Southern France, evaluation of available testing methods performances Open
Background Cefiderocol, a newly introduced siderophore cephalosporin, exhibits activity against various multidrug-resistant (MDR) Gram-negative bacilli (GNB), including producers of Ambler class A, B and D carbapenemases. The TROJAN-MDR st…
View article: Diagnosis of brucellosis: Combining tests to improve performance
Diagnosis of brucellosis: Combining tests to improve performance Open
Introduction Brucellosis, a zoonotic infectious disease caused by bacteria of the genus Brucella , remains a significant global health concern in many parts of the world. Traditional diagnostic methods, including serological tests, suffer …
View article: The zebrafish embryo model: unveiling its potential for investigating phage therapy against methicillin-resistant <i>Staphylococcus aureus</i> infection
The zebrafish embryo model: unveiling its potential for investigating phage therapy against methicillin-resistant <i>Staphylococcus aureus</i> infection Open
Staphylococcus aureus is a pathogenic bacterium responsible for a broad spectrum of infections, including cutaneous, respiratory, osteoarticular, and systemic infections. It poses a significant clinical challenge due to its ability to deve…
View article: Emergence of multidrug-resistant <i>Staphylococcus haemolyticus</i> in neonatal intensive care unit in Southern France, a genomic study
Emergence of multidrug-resistant <i>Staphylococcus haemolyticus</i> in neonatal intensive care unit in Southern France, a genomic study Open
An emergence of multidrug-resistant (MDR) Staphylococcus haemolyticus has been observed in the neonatal intensive care unit (NICU) of Nîmes University Hospital in southern France. A case-control analysis was conducted on 96 neonates, to id…
View article: Evolution of the urinary microbiota in spinal cord injury patients with decubitus ulcer: A snapshot study
Evolution of the urinary microbiota in spinal cord injury patients with decubitus ulcer: A snapshot study Open
Current microbiome investigations of patients with pressure ulcers (PU) are mainly based on wound swabs and/or biopsy sequencing, leaving the colonization scenario unclear. Urinary microbiota has been never studied. As a part of the prospe…
View article: Role of gut microbiota and bacterial translocation in acute intestinal injury and mortality in patients admitted in ICU for septic shock
Role of gut microbiota and bacterial translocation in acute intestinal injury and mortality in patients admitted in ICU for septic shock Open
Introduction Sepsis is a life-threatening organ dysfunction with high mortality rate. The gut origin hypothesis of multiple organ dysfunction syndrome relates to loss of gut barrier function and the ensuing bacterial translocation. The aim…
View article: In Vivo-Acquired Resistance to Daptomycin during Methicillin-Resistant Staphylococcus aureus Bacteremia
In Vivo-Acquired Resistance to Daptomycin during Methicillin-Resistant Staphylococcus aureus Bacteremia Open
Daptomycin (DAP) represents an interesting alternative to treat methicillin-resistant Staphylococcus aureus (MRSA) infections. Different mechanisms of DAP resistance have been described; however, in vivo-acquired resistance is uncharacteri…
View article: Evolution of the urinary microbiota in spinal cord injury patients with decubitus ulcer: a snapshot study
Evolution of the urinary microbiota in spinal cord injury patients with decubitus ulcer: a snapshot study Open
Background Current microbiome investigations of patients with pressure ulcers (PU) are mainly based on wound swabs and/or biopsy sequencing, leaving the colonization scenario unclear. Urinary microbiota has been never studied. Methods As p…
View article: Phenotypic and Genotypic Virulence Characterisation of Staphylococcus pettenkoferi Strains Isolated from Human Bloodstream and Diabetic Foot Infections
Phenotypic and Genotypic Virulence Characterisation of Staphylococcus pettenkoferi Strains Isolated from Human Bloodstream and Diabetic Foot Infections Open
Staphylococcus pettenkoferi is a recently described coagulase-negative Staphylococcus identified in human diseases, especially in infections of foot ulcers in patients living with diabetes mellitus. To date, its pathogenicity remains under…
View article: Polymicrobial Biofilm Organization of Staphylococcus aureus and Pseudomonas aeruginosa in a Chronic Wound Environment
Polymicrobial Biofilm Organization of Staphylococcus aureus and Pseudomonas aeruginosa in a Chronic Wound Environment Open
Biofilm on the skin surface of chronic wounds is an important step that involves difficulties in wound healing. The polymicrobial nature inside this pathogenic biofilm is key to understanding the chronicity of the lesion. Few in vitro mode…
View article: Bacterial Interactions in the Context of Chronic Wound Biofilm: A Review
Bacterial Interactions in the Context of Chronic Wound Biofilm: A Review Open
Chronic wounds, defined by their resistance to care after four weeks, are a major concern, affecting millions of patients every year. They can be divided into three types of lesions: diabetic foot ulcers (DFU), pressure ulcers (PU), and ve…
View article: Investigating Pathogenicity and Virulence of Staphylococcus pettenkoferi: An Emerging Pathogen
Investigating Pathogenicity and Virulence of Staphylococcus pettenkoferi: An Emerging Pathogen Open
Staphylococcus pettenkoferi is a coagulase-negative Staphylococcus identified in 2002 that has been implicated in human diseases as an opportunistic pathogenic bacterium. Its multiresistant character is becoming a major health problem, yet…
View article: Investigating pathogenicity and virulence of <i>Staphylococcus pettenkoferi:</i> an emerging pathogen
Investigating pathogenicity and virulence of <i>Staphylococcus pettenkoferi:</i> an emerging pathogen Open
Staphylococcus pettenkoferi is a coagulase-negative Staphylococcus identified in 2002 that has been implicated in human diseases as an opportunistic pathogenic bacterium. Its multiresistant character is becoming a major health problem, yet…
View article: Comparison of Barricor™ vs. lithium heparin tubes for selected routine biochemical analytes and evaluation of post centrifugation stability
Comparison of Barricor™ vs. lithium heparin tubes for selected routine biochemical analytes and evaluation of post centrifugation stability Open
By using Barricor™ tubes and prompt centrifugation, supplemental analysis or re-analysis for eight analytes including alanine aminotransferase, alkaline phosphatase, C-reactive protein, high sensitivity troponin T, lactate dehydrogenase, N…