Chongyang Duan
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View article: Graph Attention Network for Predicting Duration of Large-Scale Power Outages Induced by Natural Disasters
Graph Attention Network for Predicting Duration of Large-Scale Power Outages Induced by Natural Disasters Open
Natural disasters such as hurricanes, wildfires, and winter storms have induced large-scale power outages in the U.S., resulting in tremendous economic and societal impacts. Accurately predicting power outage recovery and impact is key to …
View article: Accelerated biological aging, inflammatory bowel disease, genetic susceptibility and life expectancy: Evidence from Multi-national Prospective Cohorts
Accelerated biological aging, inflammatory bowel disease, genetic susceptibility and life expectancy: Evidence from Multi-national Prospective Cohorts Open
View article: Astragaloside IV Improves Cognitive Impairment by Reducing β-Amyloid and Tau Protein Deposition in Hippocampal Tissue of db/db Mice: A PET/CT Imaging-Based Study
Astragaloside IV Improves Cognitive Impairment by Reducing β-Amyloid and Tau Protein Deposition in Hippocampal Tissue of db/db Mice: A PET/CT Imaging-Based Study Open
This study found that AS-IV improved cognitive function in diabetic db/db mice by reducing the buildup of Aβ and tau proteins in the hippocampus via the TNF-α-activated EGFR/NF-κB pathway.
View article: Atmospheric Pollutants, Cardiometabolic Disorders, and Dementia in Trajectory Analysis: A 13‐Year Longitudinal Cohort Study
Atmospheric Pollutants, Cardiometabolic Disorders, and Dementia in Trajectory Analysis: A 13‐Year Longitudinal Cohort Study Open
Background First cardiometabolic disorders (FCMDs) and dementia pose a significant burden on aging populations. Investigating the association between atmospheric pollutants and the progression of FCMDs and dementia is crucial. Methods A pr…
View article: Association between high-sensitivity C-reactive protein and bleeding in dual antiplatelet therapy age: a retrospective observational study
Association between high-sensitivity C-reactive protein and bleeding in dual antiplatelet therapy age: a retrospective observational study Open
Objectives The aim of the present study was to investigate the association of high-sensitivity C-reactive protein (hs-CRP) with bleeding events among patients with acute coronary syndrome (ACS) received dual antiplatelet therapy (DAPT) aft…
View article: On the current and future potential of simulations based on directed acyclic graphs
On the current and future potential of simulations based on directed acyclic graphs Open
View article: Accelerated biological aging, inflammatory bowel disease, genetic susceptibility and life expectancy: Evidence from UK Biobank and All of Us Cohorts
Accelerated biological aging, inflammatory bowel disease, genetic susceptibility and life expectancy: Evidence from UK Biobank and All of Us Cohorts Open
Background: Inflammatory bowel disease (IBD) is a chronic condition affecting individuals across all age groups. However, the association between IBD and biological aging remains unclear. Methods: We utilized data from the UK Biobank and t…
View article: 3D synergistic tumor-liver analysis further improves the efficacy prediction in hepatocellular carcinoma: a multi-center study
3D synergistic tumor-liver analysis further improves the efficacy prediction in hepatocellular carcinoma: a multi-center study Open
Background Besides tumorous information, synergistic liver parenchyma assessments may provide additional insights into the prognosis of hepatocellular carcinoma (HCC). This study aimed to investigate whether 3D synergistic tumor-liver anal…
View article: Automated Three-Dimensional Multi-Tissue Information Fusion Framework in Predicting Postoperative Overt Hepatic Encephalopathy Risk before Transjugular Intrahepatic Portosystemic Shunt: A Multi-Center Study
Automated Three-Dimensional Multi-Tissue Information Fusion Framework in Predicting Postoperative Overt Hepatic Encephalopathy Risk before Transjugular Intrahepatic Portosystemic Shunt: A Multi-Center Study Open
View article: Causal association and genetic correlation of frailty with metabolic dysfunction-associated steatotic liver disease: Epidemiological and genetic analyses
Causal association and genetic correlation of frailty with metabolic dysfunction-associated steatotic liver disease: Epidemiological and genetic analyses Open
Frailty has become a major public health issue, but its association with Metabolic dysfunction-associated steatotic liver disease (MASLD) remains controversial. We conducted an observational study of frailty and MASLD using the frailty ind…
View article: Effect of Intraoperative Midazolam on Postoperative Delirium in Older Surgical Patients: A Prospective, Multicenter Cohort Study
Effect of Intraoperative Midazolam on Postoperative Delirium in Older Surgical Patients: A Prospective, Multicenter Cohort Study Open
Background: Midazolam is a short-acting benzodiazepine frequently used in the perioperative setting. This study aimed to investigate the potential impact of intraoperative midazolam on postoperative delirium in older patients undergoing no…
View article: Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population-based cohort study
Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population-based cohort study Open
Background: Adverse effects of proton pump inhibitors (PPIs) have raised wide concerns. The association of PPIs with influenza is unexplored, while that with pneumonia or COVID-19 remains controversial. Our study aims to evaluate whether P…
View article: Author response: Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population-based cohort study
Author response: Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population-based cohort study Open
View article: Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study
Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study Open
Adverse effects of proton pump inhibitors (PPIs) have raised wide concerns. The association of PPIs with influenza is unexplored, while that with pneumonia or COVID-19 remains controversial. Our study aims to evaluate whether PPI use incre…
View article: Author response: Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study
Author response: Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study Open
Adverse effects of proton pump inhibitors (PPIs) have raised wide concerns. The association of PPIs with influenza is unexplored, while that with pneumonia or COVID-19 remains controversial. Our study aims to evaluate whether PPI use incre…
View article: Transition of cooking fuels and obesity risk in Chinese adults
Transition of cooking fuels and obesity risk in Chinese adults Open
Persistent polluting fuel use increased obesity risk while the obesity risk of the transition to cleaner fuels was similar to persistent use of cleaner fuels. The finding underscores the significance of advocating for the adoption of clean…
View article: The mediating effect of blood biomarkers in the associations between inflammatory bowel disease and incident psychiatric disorders: a prospective cohort study
The mediating effect of blood biomarkers in the associations between inflammatory bowel disease and incident psychiatric disorders: a prospective cohort study Open
Background: Despite the growing evidence of an association between inflammatory bowel disease (IBD) and psychiatric disorders, there has been limited research exploring the underlying mediating role of blood biomarkers on the gut-brain axi…
View article: Association of random glucose to albumin ratio with post-contrast acute kidney injury and clinical outcomes in patients with ST-elevation myocardial infarction
Association of random glucose to albumin ratio with post-contrast acute kidney injury and clinical outcomes in patients with ST-elevation myocardial infarction Open
Purpose Both glucose and albumin are associated with chronic inflammation, which plays a vital role in post-contrast acute kidney injury (PC-AKI). To explore the relationship between random glucose to albumin ratio (RAR) and the incidence …
View article: Hepatic-associated vascular morphological assessment to predict overt hepatic encephalopathy before TIPS: a multicenter study
Hepatic-associated vascular morphological assessment to predict overt hepatic encephalopathy before TIPS: a multicenter study Open
View article: Sleep patterns, genetic susceptibility, and digestive diseases: a large-scale longitudinal cohort study
Sleep patterns, genetic susceptibility, and digestive diseases: a large-scale longitudinal cohort study Open
Background: Sleep problems are prevalent. However, the impact of sleep patterns on digestive diseases remains uncertain. Moreover, the interaction between sleep patterns and genetic predisposition with digestive diseases has not been compr…
View article: Serum Albumin-to-Creatinine Ratio: A Novel Predictor of Pulmonary Infection in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention
Serum Albumin-to-Creatinine Ratio: A Novel Predictor of Pulmonary Infection in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention Open
A low sACR was significantly associated with elevated risk of pulmonary infection and MACE during hospitalization, as well as all-cause mortality during follow-up among patients with STEMI undergoing PCI. These findings highlighted sACR as…
View article: Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study
Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study Open
Adverse effects of proton pump inhibitors (PPIs) have raised wide concerns. The association of PPIs with influenza is unexplored, while that with pneumonia or COVID-19 remains controversial. Our study aims to evaluate whether PPI use incre…
View article: Reviewer #2 (Public Review): Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study
Reviewer #2 (Public Review): Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study Open
Adverse effects of proton pump inhibitors (PPIs) have raised wide concerns. The association of PPIs with influenza is unexplored, while that with pneumonia or COVID-19 remains controversial. Our study aims to evaluate whether PPI use incre…
View article: Author Response: Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study
Author Response: Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study Open
Adverse effects of proton pump inhibitors (PPIs) have raised wide concerns. The association of PPIs with influenza is unexplored, while that with pneumonia or COVID-19 remains controversial. Our study aims to evaluate whether PPI use incre…
View article: Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population-based cohort study
Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population-based cohort study Open
Background: Adverse effects of proton pump inhibitors (PPIs) have raised wide concerns. The association of PPIs with influenza is unexplored, while that with pneumonia or COVID-19 remains controversial. Our study aims to evaluate whether P…
View article: Reviewer #1 (Public Review): Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study
Reviewer #1 (Public Review): Associations of proton pump inhibitors with susceptibility to influenza, pneumonia, and COVID-19: Evidence from a large population based cohort study Open
Adverse effects of proton pump inhibitors (PPIs) have raised wide concerns. The association of PPIs with influenza is unexplored, while that with pneumonia or COVID-19 remains controversial. Our study aims to evaluate whether PPI use incre…
View article: Myosteatosis is an independent risk factor for overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunting
Myosteatosis is an independent risk factor for overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunting Open
Objective The relationship between skeletal muscle and adipose tissue compositions and risk of overt hepatic encephalopathy (OHE) following transjugular intrahepatic portosystemic shunt (TIPS) treatment needs to be investigated. Methods A …
View article: Real-world implementation of a multilevel interventions program to prevent mother-to-child transmission of HBV in China
Real-world implementation of a multilevel interventions program to prevent mother-to-child transmission of HBV in China Open
Reducing hepatitis B virus (HBV) mother-to-child transmission (MTCT) is a fundamental step toward the HBV elimination goal. The multicentred, multilevel SHIELD program aimed to use an intense intervention package to reduce HBV MTCT in Chin…
View article: Real-world implementation of a multilevel interventions program to prevent mother-to-child transmission of HBV in China
Real-world implementation of a multilevel interventions program to prevent mother-to-child transmission of HBV in China Open
Reducing hepatitis B virus (HBV) mother-to-child transmission (MTCT) is a fundamental step toward the HBV elimination goal. The multicentred, multilevel SHIELD program aimed to use an intense intervention package to reduce HBV MTCT in Chin…
View article: Delayed treatment effect predicting (DTEP) model for guiding immuno-oncology trial designs
Delayed treatment effect predicting (DTEP) model for guiding immuno-oncology trial designs Open
Background: The presence of delayed treatment effects (DTE) is common in immuno-oncology trials. However, conventional trial designs often overlook the potential presence of DTE, which can result in an underestimation of the required sampl…