Charing C. N. Chong
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View article: Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy
Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy Open
OBJECTIVE: Myeloid-derived suppressor cells (MDSCs) contribute to tumour immunosuppressive microenvironment and immune-checkpoint blockade resistance. Emerging evidence highlights the pivotal functions of cyclin-dependent kinases (CDKs) in…
View article: Dynamic changes of serum cytokines and their prognostic values in patients with hepatocellular carcinoma treated by thermal ablation
Dynamic changes of serum cytokines and their prognostic values in patients with hepatocellular carcinoma treated by thermal ablation Open
Background Thermal ablation is effective for early‐stage hepatocellular carcinoma (HCC). It can induce a host immune response through dynamic changes in serum cytokines. It is unknown whether this host immune response correlates with tumou…
View article: Long-term survival after extended resection combined with pericardiectomy for locally advanced intrahepatic cholangiocarcinoma: a case report
Long-term survival after extended resection combined with pericardiectomy for locally advanced intrahepatic cholangiocarcinoma: a case report Open
A 74-year-old man presented with upper gastrointestinal bleeding. Investigation revealed a locally advanced intrahepatic cholangiocarcinoma (ICC) arose from left liver invading duodenum and diaphragm. Left trisectionectomy combined with we…
View article: Defining Global Benchmarks for Laparoscopic Right Posterior Sectionectomy/H67
Defining Global Benchmarks for Laparoscopic Right Posterior Sectionectomy/H67 Open
Objective: We aimed to establish global benchmark outcomes indicators for L-RPS/H67. Background: Minimally invasive liver resections has seen an increase in uptake in recent years. Over time, challenging procedures as laparoscopic right po…
View article: The early Monash experience with targeted axillary dissection: lessons, pitfalls and practice patterns
The early Monash experience with targeted axillary dissection: lessons, pitfalls and practice patterns Open
Background and Purpose: With increasing rates of pathologic complete response (pCR) post-neoadjuvant systemic therapy, there has been an increasing focus towards de-escalating management of the node-positive axilla. Targeted axillary disse…
View article: Consensus statements on endoscopic ultrasound‐guided tissue acquisition. Guidelines from the Asian Endoscopic Ultrasound Group
Consensus statements on endoscopic ultrasound‐guided tissue acquisition. Guidelines from the Asian Endoscopic Ultrasound Group Open
Objectives This consensus was developed by the Asian EUS Group (AEG), who aimed to formulate a set of practice guidelines addressing various aspects of endoscopic ultrasound‐guided tissue acquisition (EUS‐TA). Methods The AEG initiated the…
View article: A case series of emergency pancreaticoduodenectomies: What were their indications and outcomes?
A case series of emergency pancreaticoduodenectomies: What were their indications and outcomes? Open
Emergency pancreaticoduodenectomy (EPD) is a rarely performed operation. It is important to know the indications and outcomes of EPD to have a better understanding of its application in clinical practice. A review of eight consecutive case…
View article: Propensity Score-Matching Analysis Comparing Robotic Versus Laparoscopic Limited Liver Resections of the Posterosuperior Segments
Propensity Score-Matching Analysis Comparing Robotic Versus Laparoscopic Limited Liver Resections of the Posterosuperior Segments Open
Objective: The purpose of this study was to compare the outcomes of robotic limited liver resections (RLLR) versus laparoscopic limited liver resections (LLLR) of the posterosuperior segments. Background: Both laparoscopic and robotic live…
View article: Propensity-score Matched and Coarsened-exact Matched Analysis Comparing Robotic and Laparoscopic Major Hepatectomies
Propensity-score Matched and Coarsened-exact Matched Analysis Comparing Robotic and Laparoscopic Major Hepatectomies Open
Objective: To compare the outcomes between robotic major hepatectomy (R-MH) and laparoscopic major hepatectomy (L-MH). Background: Robotic techniques may overcome the limitations of laparoscopic liver resection. However, it is unknown whet…
View article: Robotic versus laparoscopic liver resection for huge (≥10 cm) liver tumors: an international multicenter propensity-score matched cohort study of 799 cases
Robotic versus laparoscopic liver resection for huge (≥10 cm) liver tumors: an international multicenter propensity-score matched cohort study of 799 cases Open
RLR and LLR can be performed safely for selected patients with huge liver tumours with excellent outcomes. There was no significant difference in perioperative outcomes after RLR or LLR.
View article: Letter: repeat hepatic resection versus radiofrequency ablation for recurrent hepatocellular carcinoma in ideal candidates
Letter: repeat hepatic resection versus radiofrequency ablation for recurrent hepatocellular carcinoma in ideal candidates Open
LINKED CONTENT This article is linked to Tong et al papers. To view these articles, visit https://doi.org/10.1111/apt.17263 and https://doi.org/10.1111/apt.17423
View article: Sub‐classification of laparoscopic left hepatectomy based on hierarchic interaction of tumor location and size with perioperative outcomes
Sub‐classification of laparoscopic left hepatectomy based on hierarchic interaction of tumor location and size with perioperative outcomes Open
Background The aim of this multicentric study was to investigate the impact of tumor location and size on the difficulty of Laparoscopic‐Left Hepatectomy (L‐LH). Methods Patients who underwent L‐LH performed across 46 centers from 2004 to …
View article: Asia-Pacific multicentre randomized trial of laparoscopic<i>versus</i>open major hepatectomy for hepatocellular carcinoma (AP-LAPO trial)
Asia-Pacific multicentre randomized trial of laparoscopic<i>versus</i>open major hepatectomy for hepatocellular carcinoma (AP-LAPO trial) Open
Background Hepatocellular carcinoma is the sixth most common malignancy in the world. Major hepatectomy (resection of greater than or equal to three liver segments) is needed if a tumour is large or close to major blood vessels. Despite lo…
View article: Impact of tumor size on the difficulty of laparoscopic left lateral sectionectomies
Impact of tumor size on the difficulty of laparoscopic left lateral sectionectomies Open
Background Tumor size (TS) represents a critical parameter in the risk assessment of laparoscopic liver resections (LLR). Moreover, TS has been rarely related to the extent of liver resection. The aim of this study was to study the relatio…
View article: Comparison Between Minimally Invasive Right Anterior and Right Posterior Sectionectomy vs Right Hepatectomy: An International Multicenter Propensity Score–Matched and Coarsened-Exact–Matched Analysis of 1,100 Patients
Comparison Between Minimally Invasive Right Anterior and Right Posterior Sectionectomy vs Right Hepatectomy: An International Multicenter Propensity Score–Matched and Coarsened-Exact–Matched Analysis of 1,100 Patients Open
BACKGROUND: The role of minimally invasive right anterior and right posterior sectionectomy (MI-RAS/MI-RPS) for right-sided liver lesions remains debatable. Although technically more demanding, these procedures might result in faster recov…
View article: Limited liver resections in the posterosuperior segments: international multicentre propensity score-matched and coarsened exact-matched analysis comparing the laparoscopic and robotic approaches
Limited liver resections in the posterosuperior segments: international multicentre propensity score-matched and coarsened exact-matched analysis comparing the laparoscopic and robotic approaches Open
Background Limited liver resections (LLRs) for tumours located in the posterosuperior segments of the liver are technically demanding procedures. This study compared outcomes of robotic (R) and laparoscopic (L) LLR for tumours located in t…