Chongbo Yang
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View article: DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation
DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation Open
The colonic mucus barrier, dependent on goblet cell‐secreted mucin2 (Muc2), prevents microbial invasion. Compound exocytosis enables the rapid, high‐volume release of mucus from goblet cells; its underlying mechanisms, however, remain uncl…
View article: Author Correction: B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis
Author Correction: B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis Open
View article: Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis
Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis Open
View article: B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis
B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis Open
View article: Correction: Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques
Correction: Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques Open
View article: Cerebrospinal fluid outflow through skull channels instructs cranial hematopoiesis
Cerebrospinal fluid outflow through skull channels instructs cranial hematopoiesis Open
Interactions between the immune and central nervous systems strongly influence brain health. Although the blood-brain barrier restricts this crosstalk, we now know that meningeal gateways through brain border tissues, particularly dural ly…
View article: TSH Activates Macrophage Inflammation by G13- and G15-dependent Pathways
TSH Activates Macrophage Inflammation by G13- and G15-dependent Pathways Open
Thyroid-stimulating hormone (TSH) treatment activates inhibitor of NF-κB/nuclear factor κB (IκB/NFκB) and extracellular signal-regulated kinase (ERK)–P38 in macrophages, but how these pathways are activated, and how they contribute to the …
View article: Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques Open
Subclinical hypothyroidism is associated with cardiovascular diseases, yet the underlying mechanism remains largely unknown. Herein, in a common population (n = 1,103), TSH level was found to be independently correlated with both carotid p…
View article: Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice
Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice Open
View article: Role of exosome-associated microRNA in diagnostic and therapeutic applications to metabolic disorders
Role of exosome-associated microRNA in diagnostic and therapeutic applications to metabolic disorders Open
Metabolic disorders are classified clinically as a complex and varied group of diseases including metabolic syndrome, obesity, and diabetes mellitus. Fat toxicity, chronic inflammation, and oxidative stress, which may change cellular funct…