Chouki Chenaf
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View article: Risk of Relapse After COVID-19 Vaccination Among Patients With Multiple Sclerosis in France
Risk of Relapse After COVID-19 Vaccination Among Patients With Multiple Sclerosis in France Open
This study provides Class III evidence that COVID-19 vaccination does not increase the risk of severe relapse in patients with MS.
View article: Epidemiology of myasthenia gravis in France: Incidence, prevalence, and comorbidities based on national healthcare insurance claims data
Epidemiology of myasthenia gravis in France: Incidence, prevalence, and comorbidities based on national healthcare insurance claims data Open
The incidence and prevalence rates of MG are significantly higher than those previously reported in the literature and the incidence increases with age. The excess risk of cancer raises concerns for MG patients, in particular, concerning t…
View article: Mobile Health App and Web Platform (eDOL) for Medical Follow-Up of Patients With Chronic Pain: Cohort Study Involving the French eDOL National Cohort After 1 Year
Mobile Health App and Web Platform (eDOL) for Medical Follow-Up of Patients With Chronic Pain: Cohort Study Involving the French eDOL National Cohort After 1 Year Open
Background Chronic pain affects approximately 30% of the general population, severely degrades quality of life and professional life, and leads to additional health care costs. Moreover, the medical follow-up of patients with chronic pain …
View article: A 2d Hplc-Ms/Ms Method for Antibiotics Therapeutic Drug Monitoring in Plasma
A 2d Hplc-Ms/Ms Method for Antibiotics Therapeutic Drug Monitoring in Plasma Open
View article: Mobile Health App and Web Platform (eDOL) for Medical Follow-Up of Patients With Chronic Pain: Cohort Study Involving the French eDOL National Cohort After 1 Year (Preprint)
Mobile Health App and Web Platform (eDOL) for Medical Follow-Up of Patients With Chronic Pain: Cohort Study Involving the French eDOL National Cohort After 1 Year (Preprint) Open
BACKGROUND Chronic pain affects approximately 30% of the general population, severely degrades quality of life and professional life, and leads to additional health care costs. Moreover, the medical follow-up of patients with chronic pain…
View article: Chronic pain is a risk factor for incident Alzheimer’s disease: a nationwide propensity-matched cohort using administrative data
Chronic pain is a risk factor for incident Alzheimer’s disease: a nationwide propensity-matched cohort using administrative data Open
Introduction Chronic pain (CP) is one of the most disabling conditions in the elderly and seems to be a risk factor for the development of Alzheimer’s disease and related dementias (ADRD). Only one study, using national administrative heal…
View article: Real-Life Testing of the Prescription Opioid Misuse Index in French Primary Care
Real-Life Testing of the Prescription Opioid Misuse Index in French Primary Care Open
Analgesic opioid (AO) misuse by patients ranges from 0% to 50%. General practitioners are the first prescribers of AO. Our objective was to validate the Prescription Opioid Misuse Index (POMI) in primary care. We conducted a psychometric s…
View article: Cross-sectional study of the prevalence of prescription opioids misuse in French patients with chronic non-cancer pain: An update with the French version of the POMI scale
Cross-sectional study of the prevalence of prescription opioids misuse in French patients with chronic non-cancer pain: An update with the French version of the POMI scale Open
Public health issues related to chronic pain management and the risks of opioid misuse and abuse remain a challenge for practitioners. Data on the prevalence of disorders related to the use of prescribed opioids in patients suffering from …
View article: Oral Morphine as an Alternative Substitution Treatment for Opioid Use Disorder, a Rare but Non-risk-free Use
Oral Morphine as an Alternative Substitution Treatment for Opioid Use Disorder, a Rare but Non-risk-free Use Open
Background National health monitoring agencies have reported the alternative use of morphine sulfate painkiller for maintenance treatment of opioid use disorder (OUD), associated with a potential increase in overdose risk. Objectives This …
View article: Trends of influenza vaccination coverage in pregnant women: a ten-year analysis from a French healthcare database
Trends of influenza vaccination coverage in pregnant women: a ten-year analysis from a French healthcare database Open
Pregnant women have a high risk of severe influenza, associated with obstetrical complications. The World Health Organization (WHO) has recommended influenza vaccination for all pregnant women since 2012. The vaccination coverage remains l…
View article: Transcultural validation of a French–European version of the Prescription Opioid Misuse Index Scale (POMI-5F)
Transcultural validation of a French–European version of the Prescription Opioid Misuse Index Scale (POMI-5F) Open
View article: Opioid Analgesic Prescription in French Children: A National Population-Based Study
Opioid Analgesic Prescription in French Children: A National Population-Based Study Open
Codeine use was restricted in 2013 and is currently contraindicated for children below the age of 12 years. We examined how the prescription of opioid analgesics in children in France evolved between 2012 and 2018. Our population-based stu…
View article: Evolution de la couverture vaccinale antigrippale chez la femme enceinte de 2009 à 2018
Evolution de la couverture vaccinale antigrippale chez la femme enceinte de 2009 à 2018 Open
International audience
View article: Prevalence and Characteristics of Chronic Pain in Buprenorphine and Methadone-Maintained Patients
Prevalence and Characteristics of Chronic Pain in Buprenorphine and Methadone-Maintained Patients Open
Chronic pain and substance use disorders frequently co-occur. Indeed, chronic pain is highly prevalent, affecting 23–68% of patients receiving opioid agonist treatments (OAT) worldwide. The majority of available estimates come from America…
View article: Analgesic opioid use disorders in patients with chronic non-cancer pain: A holistic approach for tailored management
Analgesic opioid use disorders in patients with chronic non-cancer pain: A holistic approach for tailored management Open
View article: Trajectories of antidepressant drugs during pregnancy: A cohort study from a community‐based sample
Trajectories of antidepressant drugs during pregnancy: A cohort study from a community‐based sample Open
Aims The aim of this study was to monitor the trajectories of antidepressant use during pregnancy and the postpartum period among women chronically treated with antidepressants before their pregnancy, and to assess characteristics associat…
View article: Opioid epidemic: Does rheumatological practice favors risk for patients? National survey on rheumatologists’ opioid prescriptions and compliance to guidelines for strong opioid prescription
Opioid epidemic: Does rheumatological practice favors risk for patients? National survey on rheumatologists’ opioid prescriptions and compliance to guidelines for strong opioid prescription Open
View article: Moderate-to-severe eosinophilia induced by treatment with immune checkpoint inhibitors: 37 cases from a national reference center for hypereosinophilic syndromes and the French pharmacovigilance database
Moderate-to-severe eosinophilia induced by treatment with immune checkpoint inhibitors: 37 cases from a national reference center for hypereosinophilic syndromes and the French pharmacovigilance database Open
A better understanding of immune-related adverse events is essential for the early detection and appropriate management of these phenomena. We conducted an observational study of cases recorded at the French reference center for hypereosin…
View article: Risk assessment of using off‐label morphine sulfate in a population‐based retrospective cohort of opioid‐dependent patients
Risk assessment of using off‐label morphine sulfate in a population‐based retrospective cohort of opioid‐dependent patients Open
Aims Several addictovigilance studies have described the off‐label use of morphine sulfate (MS) for nonchronic pain in opioid use disorder (OUD) patients as an alternative to conventional opioid substitution treatments (OSTs). This study p…
View article: Chronic Pain Opioid-Maintained Patients Receive Less Analgesic Opioid Prescriptions
Chronic Pain Opioid-Maintained Patients Receive Less Analgesic Opioid Prescriptions Open
Treating pain and opioid use disorder represents a clinical challenge. While most studies that have assessed opioid analgesic use in opioid substitution treatment (OST) patients primarily address opioid analgesic misuse (1, 2), only few st…
View article: Development of\nthe First Two-Pore Domain Potassium\nChannel TWIK-Related K<sup>+</sup> Channel 1‑Selective Agonist\nPossessing in Vivo Antinociceptive Activity
Development of\nthe First Two-Pore Domain Potassium\nChannel TWIK-Related K<sup>+</sup> Channel 1‑Selective Agonist\nPossessing in Vivo Antinociceptive Activity Open
The\nTWIK-related K+ channel, TREK-1, has recently emerged\nas an attractive therapeutic target for the development of a novel\nclass of analgesic drugs, suggesting that activation of TREK-1 could\nresult in pain inhibition. Her…
View article: Assessment of the effectiveness and safety of Ethosuximide in the Treatment of non-Diabetic Peripheral Neuropathic Pain: EDONOT—protocol of a randomised, parallel, controlled, double-blinded and multicentre clinical trial
Assessment of the effectiveness and safety of Ethosuximide in the Treatment of non-Diabetic Peripheral Neuropathic Pain: EDONOT—protocol of a randomised, parallel, controlled, double-blinded and multicentre clinical trial Open
Introduction Currently available analgesics are ineffective in 30–50% of patients suffering from neuropathic pain and often induce deleterious side effects. T-type calcium channel blockers (mibefradil, ethosuximide, NNC 55-0396) are of gre…
View article: Poster Abstracts
Poster Abstracts Open
Special Issue: Abstracts of the 20th Annual Meeting of French Society of Pharmacology and Therapeutics, 37th Pharmacovigilance Meeting, 17th APNET Seminar, 14th CHU CIC Meeting, 19–21 April 2016, Nancy, France