Explanipedia

Assessment of Coagulopathy in Children with Acute Lymphoblastic Leukemia Receiving L-asparaginase During Induction Phase of Chemotherapy Open

Syamsuddin Mahmud, Md Imrul Kaes, Md. Nazrul Islam Mondal, Niaz Mahmud, Chowdhury Yakub Jamal · 2025

Background: Acute lymphoblastic leukemia (ALL) is among the most common and curable cancers in pediatric populations. A notable complication that can occur during its treatment is coagulopathy, often resulting from the use of chemotherapeu…

Evaluation of Lipid Profile among Transfusion Dependent Thalassemic Children and Assessing Its Correlation with Serum Ferritin Open

Tandra Chakma, Chowdhury Yakub Jamal, Abdul Khaleque, K. R. Islam, Kawsari Akhter , et al. · 2025

Background: Thalassemias are inherited hemoglobin disorders that necessitate lifelong blood transfusions. Patients having transfusion-dependent thalassemia (TDT) experience excess iron deposition in different organs. Due to excess of iron …

Treatment Outcome of Childhood Hepatoblastoma: A Single Centre Experience in Bangladesh Open

Farida Yasmin, Chowdhury Yakub Jamal, Afiqul Islam, Md. Anwarul Karim, Zannat Ara , et al. · 2025

Transfusion-dependent b-Thalassemia Major Bangladeshi Child Treated Successfully with Combination of Hydroxyurea and Low- Dose Thalidomide : A Case Report Open

Md. Anwarul Karim, Sohail Akhter, Chowdhury Yakub Jamal · 2024

Beta thalassemia results from absent or reduced production of beta globin gene leading to excess of alpha chain which causes ineffective erythropoiesis and marked anemia. b-thalassemia major patients usually present early within 2 years of…

Risk factors of asparaginase-associated pancreatitis in children with acute lymphoblastic leukaemia Open

Abu Haider Mohammad Raziul, Chowdhury Yakub Jamal, Nafisa Yesmin, Niaz Mahmud, Nazneen Sultana · 2024

Background: Acute lymphoblastic leukaemia (ALL) is the top childhood cancer, with survival rates of 80–85%. Attention now focuses on treatment complications. Pancreatitis, linked to Asparaginase in ALL therapy, remains poorly understood de…

Safety & Efficacy of Thalidomide in Children with Transfusion DependentThalassemia: a Quasi Randomized Controlled Trial in a Tertiary Care Hospital in Bangladesh Open

Md. Mehedi Hasan, Md. Anwarul Karim, ATM Atikur Rahman, Chowdhury Yakub Jamal, Md Salauddin Mia , et al. · 2024

Background:Children with transfusion-dependent thalassemia (TDT) face a significant health burden. Though regular blood transfusions are life-saving, they carry risks of infection and iron overload. Thalidomide shows promise for increasing…

Riddles of Lupus Anticoagulant in children Open

Chowdhury Yakub Jamal · 2024

not available BANGLADESH J CHILD HEALTH 2022; VOL 46 (3) : 100-101

Reproducibility of Naked Eye Single Tube Red cell Osmotic Fragility Test (NESTROFT) as a screening test for the detection of b thalassemia and Hemoglobin E traits with the variation of reading time Open

Md. Anwarul Karim, Chowdhury Yakub Jamal, MA Mannan Mia · 2024

Background: Though 0.36% NaCl buffered solution has been used as an effective reagent for carrying out Naked Eye Single Tube Red cell Osmotic Fragility Test (NESTROFT) as a screening test for the detection of b thalassemia and Hemoglobin E…

Malnutrition as a predictor of adverse outcomes of febrile neutropenia in children with acute lymphoblastic leukemia during induction phase chemotherapy Open

Farzana Alam Mou, Mst. Arafatara Khatun, Umme Nusrat Ara, Tania Sultana, Sohail Akhter , et al. · 2023

Background: Adequate nutrition is an important concern in children with leukemia. Malnutrition impairs immune function, leading to increased incidence of infection, poor quality of life, as well as death. Febrile neutropenia (FN) has a hig…

Time of Attainment of Clinical Remission and Peripheral Blood Count Recovery during Induction Chemotherapy for Childhood Acute Lymphoblastic Leukemia Open

Mst. Arafatara Khatun, Chowdhury Yakub Jamal, ATM Atikur Rahman, Md. Anwarul Karim, Farzana Alam Mou , et al. · 2023

Background: Acute lymphoblastic leukemia(ALL) is the most common pediatric malignancy. Infection and bleeding are the leading cause of death during induction chemotherapy in childhood ALL. So, proper knowledge about anticipated infection a…

Influence of Nutritional Status of Children with Acute Lymphoblastic Leukemia (ALL) on Treatment Outcome after Completion of Induction Open

SM Rezanur Rahman, Chowdhury Yakub Jamal, Akm Amirul Morshed Khasru, Zohora Jameela Khan, Mehnaz Akter , et al. · 2023

Background: Malnutrition and cancer both influences tolerance and response to treatment especially ALL. Malnutrition increases morbidity, mortality, reduces the effectiveness of treatment and impairs the quality of life significantly. Obje…

Rate of Cardiotoxicity in Childhood Acute Lymphoblastic Leukemia Treated with Daunorubicin Using Echocardiography and Troponin I Open

Tania Sultana, Tapas Chowdhury, Farzana Islam, Umme Nusrat Ara, Chowdhury Shamsul Hoque Kibria , et al. · 2023

Background and Aim: Acute lymphoblastic leukemia (ALL) is the commonest malignancy in childhood. Childhood ALL Survivors have a lifelong increased risk for cardiovascular morbidity and mortality compared to the general population, mainly c…

Outcome of neutropenic enteropathy during induction phase of treatment of childhood acute lymphoblastic leukemia Open

Yesmin Tanjin Jahan, Md. Anwarul Karim, Chowdhury Yakub Jamal, ATM Atikur Rahman · 2023

Background: Neutropenic enteropathy is one of the important causes of death during intensive phase of chemotherapy in children with acute lymphoblastic leukemia (ALL). It follows a prolonged course of neutropenia and carries a mortality ra…

Evaluation of hematological and biochemical factors of hypertension during the induction chemotherapy for childhood acute lymphoblastic leukemia Open

Mousumi Saha, Chowdhury Yakub Jamal, Shahinoor Akter Soma, Md Imrul Kaes · 2023

Background: Acute lymphoblastic leukemia (ALL) is a prevalent childhood cancer, accounting for approximately 25% of all pediatric cancer cases. The incidence of hypertension in ALL patients is significantly higher compared to the general p…

Outcome of Febrile Neutropenia in Children with Cancer: Experience from a Tertiary Health Care Center Open

Md Imrul Kaes, Afiqul Islam, Chowdhury Yakub Jamal, Mousumi Saha, Indira Chowdhury · 2023

Background: Febrile neutropenia (FN) is a serious event in children with cancer; associated with various complications and mentionable adverse outcome.Objective: To identify the outcome of febrile neutropenia in children with cancer.Materi…

Vincristine induced peripheral neuropathy in children undergoing chemotherapy for acute lymphoblastic leukaemia during induction Open

Nazneen Sultana, Chowdhury Yakub Jamal, ATM Atikur Rahman, Shahinoor Akter Soma, Md. Nazrul Islam Mondal , et al. · 2023

Background: Vincristine is an anticancer agent administered to all children with acute lymphoblastic leukemia (ALL), and peripheral neuropathy is the major dose-limiting toxicity of this therapy. As cure rates of childhood ALL exceeds 80%,…

Change of lipid profile in children with acute lymphoblastic leukemia due to induction chemotherapy in a tertiary care hospital of Bangladesh Open

Rasel Siddique, Zamil Ahmed Manik, AZM Rayhanur Rahman, Samina Masud Santa, Mehedi Hasan , et al. · 2023

Background: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. In the Department of Paediatric Haematology and Oncology of Bangabandhu Sheikh Mujib Medical University (BSMMU), 58% of ALL cases were recorded among 4…

Infectious Complication During Induction Chemotherapy in Children with Acute Myeloid Leukemia- A Single Center Study Open

Indira Chowdhury, Chowdhury Yakub Jamal, Shahinoor Akter Soma, Farah Diba, Imrul Kaes , et al. · 2022

Background: Acute Myeloid Leukemia (AML) contributes to about 20% of leukemia. Most of the AML patients suffer from infection. Objective: To evaluate the rate of infection, type and site of infection, organisms responsible for infection a…

Incidence and treatment outcome of childhood lymphomas in a tertiary care hospital of a developed country: a study in Combined Military Hospital Bangladesh Open

Kamrun Nahar, Ahmed Rashidul Hasan, Shormin Ara Ferdousi, Md Azizul Islam, Afiqul Islam , et al. · 2022

Background: Over the years incidence of childhood cancer has been increasing. Being the third most common childhood malignancy, Lymphoma also achieved improved survival and reduced mortality along with other cancer in children & adolescent…

Etiology and Outcome of Seizures in Children during Induction Remission Chemotherapy for Acute Lymphoblastic Leukaemia Open

Shahinoor A. Soma, Chowdhury Yakub Jamal, Indira Chowdhury · 2022

Seizure is one of the most frequent neurological complication and morbid phenomenon among children receiving chemotherapy for acute lymphoblastic leukemia. As overall survival of children with acute lymphoblastic leukemia is improving, now…

Frequency and Risk Factors of Seizures in Children During Induction Remission Chemotherapy for Acute Lymphoblastic Leukemia (ALL) Open

Shahinoor Akter Soma, Chowdhury Yakub Jamal, Indira Chowdhury, Farah Diba, Mousumi Saha · 2022

Background: Seizure is one of the most common CNS complications among patients receiving chemotherapy for acute lymphoblastic leukemia (ALL). Seizures are seen in 8-13% of patients with ALL. Most seizure occurs during the induction and con…

Clinico-pathological Profile of Childhood Nonhodgkin Lymphoma (NHL) in A Tertiary Care Hospital in Bangladesh Open

Kamrun Nahar, Ahmed Rashidul Hasan, Afiqul Islam, Chowdhury Yakub Jamal · 2022

Background: Non-Hodgkin Lymphoma (NHL) is the third most common childhood malignancy. With histopathology based intensive chemotherapy and CNS-directed therapy, survival can reach more than 80%. Objective: The study was conducted to obser…

Nutritional Status of the Children with Acute Lymphoblastic Leukemia at Diagnosis and after Completion of Induction Open

Noor-A-Sabah Liza, S. M. Rezanur Rahman, Afiqul Islam, Chowdhury Yakub Jamal, Mohosina Sultana Setu , et al. · 2021

Background: Adequate nutrition is an important concern in children with leukemia. Malnutrition and weight lost are common and are due to verity of mechanism involving the tumor, the host response to the tumor such as infection and pharmaco…

Invasive Fungal Infections in Children with Hematological Malignancy Open

Chowdhury Yakub Jamal, Ismet Nigar · 2021

Invasive fungal infections (IFI) are a major cause of morbidity and mortality in patients with haematolgical malignancies. Factors that appear to be associated with IFIs in both children and adults in this severely immunosuppressed populat…

Assessment of Iron Status in Hemoglobin E and b Thalassemia Carriers Open

Md. Anwarul Karim, Chowdhury Yakub Jamal, Md Selimuzzaman, MA Mannan Miah · 2021

Background: About 10-13% people of Bangladesh are carrier of HbE and b- thalassaemia. Many program have been taken by Government and NGOs for supplementation of iron to raise hemoglobin level of children which may not be beneficial or migh…

A Case Report on a Rare Inherited Bone Marrow Failure Syndrome: Dyskeratosis Congenita. Open

Md. Anwarul Karim, Chowdhury Yakub Jamal, Md Imrul Kaes, Khondaker Mobasher Ahmed · 2020

Dyskeratosis congenita is a rare type of inherited bone marrow failure syndromes (IBMFs) characterized by ectodermal dysplasia, bone marrow failure and cancer predisposition. Accelerated telomere shortening is supposed to be the causal mec…

The Higher Fatality Rate of Children from COVID-19 in Bangladesh Is it Ethnicity or Malnutrition or Else? Open

Chowdhury Yakub Jamal, Shahana A Rahman · 2020

Not Available Bangladesh J Child Health 2020; VOL 44 (1) :1-3

Haematological Toxicities Following Treatment of Childhood Hepatoblastoma with Intensive Multiagent Chemotherapy Open

Farida Yasmin, Chowdhury Yakub Jamal, Afiqul Islam, Md. Anwarul Karim, Mamtaz Begum · 2020

Background: Hepatoblastoma is a rare malignant liver tumour that occurs almost exclusively in childhood. Although surgical resection is the foundation of curative therapy, with the use of effective neoadjuvant and adjuvant chemotherapy the…

Risk Prediction of Febrile Neutropenia in Children with Acute Lymphoblastic Leukemia Open

Lutfor Rahman Mollah, Amirul Morshed Khasru, Md. Bani Yeamin, Zannat Ara, Tanvir Ahamed , et al. · 2020

Background: Fever in severe chemotherapy induced neutropenic patients is the most frequent manifestation of a potentially lethal complication of current intensive chemotherapy regimen. Objective: The aim of this study is identification of …

Pattern of Enteropathogens during Diarrhoeal Episode in Children with Haematological Malignancy Open

Ferdousi Begum, Rashidul Haque, ATM Atikur Rahman, Farida Yasmin, Chowdhury Yakub Jamal , et al. · 2020

Background: Haematological malignancies comprise 82% of all malignancies in children at the department of Paediatric Haematology and Oncology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh; Gastro-intestinal infections we…

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