Chris F. Harrington
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View article: Central Serous Chorioretinopathy Diagnosed by Emergency Practitioner‐Performed Ocular Point‐Of‐Care Ultrasonography
Central Serous Chorioretinopathy Diagnosed by Emergency Practitioner‐Performed Ocular Point‐Of‐Care Ultrasonography Open
Introduction Central serous chorioretinopathy (CSCR) is a common cause of acute, monocular vision loss amongst men aged 40–50 years. Diagnosis is typically multimodal, requiring advanced ophthalmic imaging. These techniques are not readily…
View article: Rationale and design of a randomised trial of trientine in patients with hypertrophic cardiomyopathy
Rationale and design of a randomised trial of trientine in patients with hypertrophic cardiomyopathy Open
Aims Hypertrophic cardiomyopathy (HCM) is characterised by left ventricular hypertrophy (LVH), myocardial fibrosis, enhanced oxidative stress and energy depletion. Unbound/loosely bound tissue copper II ions are powerful catalysts of oxida…
View article: Review: Advances in the Accuracy and Traceability of Metalloprotein Measurements Using Isotope Dilution Inductively Coupled Plasma Mass Spectrometry
Review: Advances in the Accuracy and Traceability of Metalloprotein Measurements Using Isotope Dilution Inductively Coupled Plasma Mass Spectrometry Open
Advances in inductively coupled plasma mass spectrometry and the methods used to prepare isotopically enriched standards, allow for the high accuracy measurement of metalloproteins by isotope dilution mass spectrometry. This technique has …
View article: O32: The Healthy Oregon Project: A successful statewide model for low-cost genetic screening for inherited cancer and familial hypercholesterolemia*
O32: The Healthy Oregon Project: A successful statewide model for low-cost genetic screening for inherited cancer and familial hypercholesterolemia* Open
View article: Guideline Review: European Association for the Study of Liver (EASL) Clinical Practice Guidelines on Haemochromatosis
Guideline Review: European Association for the Study of Liver (EASL) Clinical Practice Guidelines on Haemochromatosis Open
View article: A Proposed Concept Model for Cancer Risk in Nigerian Electronic Waste Exposure – A Brief Report
A Proposed Concept Model for Cancer Risk in Nigerian Electronic Waste Exposure – A Brief Report Open
Aim: This report aims to render a proposed concept model for cancer risk in Nigerian electronic waste exposure by making deductions from data on the assessment of Nigerians' exposure to toxic metals in e-waste, using biomarkers of e…
View article: Local Anatomic Precursors to New-Onset Geographic Atrophy in Age-Related Macular Degeneration as Defined on OCT
Local Anatomic Precursors to New-Onset Geographic Atrophy in Age-Related Macular Degeneration as Defined on OCT Open
View article: RNA-Seq of human whole blood: Evaluation of globin RNA depletion on Ribo-Zero library method
RNA-Seq of human whole blood: Evaluation of globin RNA depletion on Ribo-Zero library method Open
Peripheral blood is a highly accessible biofluid providing a rich source of information about human physiology and health status. However, for studies of the blood transcriptome with RNA sequencing (RNA-Seq) techniques, high levels of hemo…
View article: Atomic spectrometry update: review of advances in elemental speciation
Atomic spectrometry update: review of advances in elemental speciation Open
This review covers advances in elemental speciation by a range of coupled techniques, including HPLC-ICP-MS, HPLC-HG-AFS and GC-ICP-MS.
View article: Biomedical copper speciation in relation to Wilson’s disease using strong anion exchange chromatography coupled to triple quadrupole inductively coupled plasma mass spectrometry
Biomedical copper speciation in relation to Wilson’s disease using strong anion exchange chromatography coupled to triple quadrupole inductively coupled plasma mass spectrometry Open
Biomedical analytical methods often rely on indirect measurements, such as immunoassays, which can lack effective metrological traceability. In the nephelometric determination of ceruloplasmin (Cp), an important protein whose circulating l…
View article: Is the synovial fluid cobalt-to-chromium ratio related to the serum partitioning of metal debris following metal-on-metal hip arthroplasty?
Is the synovial fluid cobalt-to-chromium ratio related to the serum partitioning of metal debris following metal-on-metal hip arthroplasty? Open
Objectives We investigated the reliability of the cobalt-chromium (CoCr) synovial joint fluid ratio (JFR) in identifying the presence of a severe aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL) response and/or suboptimal …
View article: Analysis of soluble or titanium dioxide derived titanium levels in human whole blood: consensus from an inter-laboratory comparison
Analysis of soluble or titanium dioxide derived titanium levels in human whole blood: consensus from an inter-laboratory comparison Open
Exposure to titanium (Ti),viathe ingestion of pigment grade Ti dioxide (TiO2), is commonplace for westernised populations.
View article: Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration
Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration Open
View article: Spectral Domain Optical Coherence Tomography 2-Year Localized Precursors to New Onset Geographic Atrophy in Age-Related Macular Degeneration
Spectral Domain Optical Coherence Tomography 2-Year Localized Precursors to New Onset Geographic Atrophy in Age-Related Macular Degeneration Open
View article: The clinical and operational consequences of prolonged occupancy strain and the use of non-intensive care beds to deliver critical care in a central london teaching hospital
The clinical and operational consequences of prolonged occupancy strain and the use of non-intensive care beds to deliver critical care in a central london teaching hospital Open
Since 2000, there has been a marked reduction in non-clinical critical care transfers in England. ICNARC have reported that this has been associated with a reduction in case-mix adjusted mortality (1). One consequence has been the need to …