Christopher Gill
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View article: Estimating the value of combination vaccines: a methodological framework
Estimating the value of combination vaccines: a methodological framework Open
Combination vaccines combine several components in a single dose administration. They offer programmatic and public health advantages, particularly as vaccine schedules become increasingly crowded. They are often more expensive to develop …
View article: Longitudinal Analysis of Nasopharyngeal Microbial Risk Markers for Fatal Acute Febrile Illness in a Zambian Birth Cohort
Longitudinal Analysis of Nasopharyngeal Microbial Risk Markers for Fatal Acute Febrile Illness in a Zambian Birth Cohort Open
Background Fatal acute febrile illness (fAFI) is a known predecessor of many infant mortality events in low-resource settings, but early risk markers for this condition remain poorly understood. Nasopharyngeal (NP) microbiome patterns may …
View article: Shining light on the dark matter of pertussis: evidence for an asymptomatic carriage state from a longitudinal cohort of mother/infant dyads
Shining light on the dark matter of pertussis: evidence for an asymptomatic carriage state from a longitudinal cohort of mother/infant dyads Open
Pertussis remains an enigma partly due to the uncertain impact of asymptomatic cases on transmission. Contributing to this knowledge gap is a lack of high-quality disease surveillance, particularly in those low- and middle-income countries…
View article: Shining light on the dark matter of pertussis: evidence for an asymptomatic carriage state from a longitudinal cohort of mother/infant dyads
Shining light on the dark matter of pertussis: evidence for an asymptomatic carriage state from a longitudinal cohort of mother/infant dyads Open
Pertussis remains an enigma partly due to the uncertain impact of asymptomatic cases on transmission. Contributing to this knowledge gap is a lack of high-quality disease surveillance, particularly in those low- and middle-income countries…
View article: Present or Absent: Risks and protective factors of sudden infant death syndrome (SIDS) in the Zambian context
Present or Absent: Risks and protective factors of sudden infant death syndrome (SIDS) in the Zambian context Open
View article: The P4-phospholipid flippase Atp11a is required for maintenance of eye and ear structure in zebrafish
The P4-phospholipid flippase Atp11a is required for maintenance of eye and ear structure in zebrafish Open
The atp11a gene encodes a phospholipid flippase protein required to flip phosphatidylserine (PS) and phosphatidylethanolamine (PE) from the outer leaflet of the cytoplasmic membrane to the inner leaflet. Mutations in ATP11A have been descr…
View article: Risk of hospitalization or death does not differ in children exposed to HIV, yet uninfected compared to nonexposed peers in Lusaka, Zambia
Risk of hospitalization or death does not differ in children exposed to HIV, yet uninfected compared to nonexposed peers in Lusaka, Zambia Open
Objective: Increased mortality and morbidity has been observed among children who are HIV-exposed, uninfected (CHEU). It is unknown if health disparities remain despite promotion of exclusive breastfeeding and adoption of universal combina…
View article: Shining light on the dark matter of pertussis: evidence for an asymptomatic carriage state from a longitudinal cohort of mother/infant dyads
Shining light on the dark matter of pertussis: evidence for an asymptomatic carriage state from a longitudinal cohort of mother/infant dyads Open
Pertussis remains an enigma partly due to the uncertain impact of asymptomatic cases on transmission. Contributing to this knowledge gap is a lack of high-quality disease surveillance, particularly in those low- and middle-income countries…
View article: The (Poly)Phenolic Content of the Armagh Bramley Apple: Effects of Horticultural Practices
The (Poly)Phenolic Content of the Armagh Bramley Apple: Effects of Horticultural Practices Open
View article: The (Poly)Phenolic Content of the Armagh Bramley Apple: Effects of Horticultural Practices
The (Poly)Phenolic Content of the Armagh Bramley Apple: Effects of Horticultural Practices Open
View article: Characterization of longitudinal nasopharyngeal microbiome patterns in maternally HIV-exposed Zambian infants
Characterization of longitudinal nasopharyngeal microbiome patterns in maternally HIV-exposed Zambian infants Open
Background Previous studies of infants born to HIV-positive mothers have linked HIV exposure to poor outcomes from gastrointestinal and respiratory illnesses, and to overall increased mortality rates. The mechanism behind this is unknown, …
View article: Preterm birth among women with HIV: impact of preconception cART initiation
Preterm birth among women with HIV: impact of preconception cART initiation Open
Objective: To examine the risk of preterm birth (PTB) and small for gestational age (SGA) among women with HIV compared to women without HIV. Secondary objectives were to explore the role of maternal immune activation (IA) and effect of cA…
View article: Single-test syphilis serology: A case of not seeing the forest for the trees
Single-test syphilis serology: A case of not seeing the forest for the trees Open
Introduction There have been few empirical studies for diagnostic test accuracy of syphilis using a sequence of rapid tests in populations with low prevalence of syphilis such as pregnant women. This analysis describes syphilis test positi…
View article: Nasopharyngeal Dysbiosis Precedes the Development of Lower Respiratory Tract Infections in Young Infants, a Longitudinal Infant Cohort Study
Nasopharyngeal Dysbiosis Precedes the Development of Lower Respiratory Tract Infections in Young Infants, a Longitudinal Infant Cohort Study Open
Background Infants suffering from lower respiratory tract infections (LRTIs) have distinct nasopharyngeal (NP) microbiome profiles that correlate with severity of disease. Whether these profiles precede the infection or are a consequence o…
View article: Author Correction: Using mortuary and burial data to place COVID-19 in Lusaka, Zambia within a global context
Author Correction: Using mortuary and burial data to place COVID-19 in Lusaka, Zambia within a global context Open
View article: Curated and Annotated Dataset of Lung US Images in Zambian Children with Clinical Pneumonia
Curated and Annotated Dataset of Lung US Images in Zambian Children with Clinical Pneumonia Open
See also the commentary by Sitek in this issue. Supplemental material is available for this article.
View article: The role of stigma in cannabis use disclosure: an exploratory study
The role of stigma in cannabis use disclosure: an exploratory study Open
Background Although cannabis use incidence, societal acceptance, and legislation all trend positively, cannabis remains federally illegal in the USA. Prior studies have revealed that patients are reluctant to disclose their cannabis use hi…
View article: Analysis of nasopharyngeal microbiome patterns in Zambian infants with fatal acute febrile illness
Analysis of nasopharyngeal microbiome patterns in Zambian infants with fatal acute febrile illness Open
Introduction Associative connections have previously been identified between nasopharyngeal infections and infant mortality. The nasopharyngeal microbiome may potentially influence the severity of these infections. Methods We conducted an …
View article: An Exploratory Study of the Association Between Preoperative Pain Catastrophizing Scale Scores and Postoperative Pain Experience in Total Knee Arthroplasty
An Exploratory Study of the Association Between Preoperative Pain Catastrophizing Scale Scores and Postoperative Pain Experience in Total Knee Arthroplasty Open
Introduction Opiate misuse is increasingly common and can result from a single opiate exposure. High pain catastrophizing scores have been linked with greater reported pain and increased opiate use in outpatient studies, but this associati…
View article: Using mortuary and burial data to place COVID-19 in Lusaka, Zambia within a global context
Using mortuary and burial data to place COVID-19 in Lusaka, Zambia within a global context Open
View article: Qualitative assessment of infant sleep practices and other risk factors of sudden infant death syndrome (SIDS) among mothers in Lusaka, Zambia
Qualitative assessment of infant sleep practices and other risk factors of sudden infant death syndrome (SIDS) among mothers in Lusaka, Zambia Open
View article: Young Zambian infants with symptomatic RSV and pertussis infections are frequently prescribed inappropriate antibiotics: a retrospective analysis
Young Zambian infants with symptomatic RSV and pertussis infections are frequently prescribed inappropriate antibiotics: a retrospective analysis Open
Pediatric community-acquired pneumonia (CAP) remains a pressing global health concern, particularly in low-resource settings where diagnosis and treatment rely on empiric, symptoms-based guidelines such as the WHO’s Integrated Management o…
View article: Postmortem Nasopharyngeal Microbiome Analysis of Zambian Infants With and Without Respiratory Syncytial Virus Disease: A Nested Case Control Study
Postmortem Nasopharyngeal Microbiome Analysis of Zambian Infants With and Without Respiratory Syncytial Virus Disease: A Nested Case Control Study Open
Background: Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis and lower respiratory tract infections in children in their first year of life, disproportionately affecting infants in developing countries. Previous …
View article: The apparent burden of unexplained sudden infant deaths in Lusaka, Zambia: Findings from analysis of verbal autopsies
The apparent burden of unexplained sudden infant deaths in Lusaka, Zambia: Findings from analysis of verbal autopsies Open
Background: The contribution of sudden unexpected infant death (SUID) has received little attention in global health. The objective of this study was to estimate the burden of SUID in Lusaka, Zambia. Methods: Verbal autopsies were conducte…
View article: Qualitative assessment of infant sleep practices and other risk factors of sudden infant death syndrome (SIDS) in Lusaka, Zambia
Qualitative assessment of infant sleep practices and other risk factors of sudden infant death syndrome (SIDS) in Lusaka, Zambia Open
Background: There is very little information on the beliefs and perceptions of mothers about SIDS and its related risk factors in Africa. To better understand parental decisions about infant sleep practices and other risk factors for SIDS,…
View article: Apparent SIDS in Lusaka, Zambia
Apparent SIDS in Lusaka, Zambia Open
This dataset contains supplementary tables including SAS code and dataset used for estimating the apparent burden of sudden unexplained infant deaths (SUID) in Lusaka, Zambia. The dataset is from verbal autopsies conducted on infants who d…
View article: Apparent SIDS in Lusaka, Zambia
Apparent SIDS in Lusaka, Zambia Open
This dataset contains supplementary tables including SAS code and dataset used for estimating the apparent burden of sudden unexplained infant deaths (SUID) in Lusaka, Zambia. The dataset is from verbal autopsies conducted on infants who d…
View article: Apparent SIDS in Lusaka, Zambia
Apparent SIDS in Lusaka, Zambia Open
This dataset contains supplementary tables including SAS code and dataset used for estimating the apparent burden of sudden unexplained infant deaths (SUID) in Lusaka, Zambia. The dataset is from verbal autopsies conducted on infants who d…
View article: Post-mortem Nasopharyngeal Microbiome Analysis of Zambian Infants with and without Respiratory Syncytial Virus Disease: A Nested Case Control Study
Post-mortem Nasopharyngeal Microbiome Analysis of Zambian Infants with and without Respiratory Syncytial Virus Disease: A Nested Case Control Study Open
Background Respiratory Syncytial Virus (RSV) is the most common cause of bronchiolitis and lower respiratory tract infections in children in their first year of life, disproportionately affecting infants in developing countries. Previous s…
View article: What is the prevalence of COVID-19 detection by PCR among deceased individuals in Lusaka, Zambia? A postmortem surveillance study
What is the prevalence of COVID-19 detection by PCR among deceased individuals in Lusaka, Zambia? A postmortem surveillance study Open
Objectives To determine the prevalence of COVID-19 postmortem setting in Lusaka, Zambia. Design A systematic, postmortem prevalence study. Setting A busy, inner-city morgue in Lusaka. Participants We sampled a random subset of all decedent…