Chris M. Gregory
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View article: Walking gait biomechanics in individuals with quadriceps tendon autograft anterior cruciate ligament reconstruction
Walking gait biomechanics in individuals with quadriceps tendon autograft anterior cruciate ligament reconstruction Open
Introduction Walking is a vital movement, corresponding to physical activity, health, and independent living. Persistent abnormal lower extremity kinetics and kinematics during walking may influence long-term joint health. Anterior cruciat…
View article: Item-Level Psychometrics for the Functional Gait Assessment in Persons With Stroke
Item-Level Psychometrics for the Functional Gait Assessment in Persons With Stroke Open
Rasch analysis supports the use of the FGA to measure walking balance ability in ambulatory persons with chronic stroke. An FGA keyform can provide instantaneous interval measurement for individuals.
View article: Musculoskeletal and body composition response to high-dose testosterone with finasteride after chronic incomplete spinal cord injury—a randomized, double-blind, and placebo-controlled pilot study
Musculoskeletal and body composition response to high-dose testosterone with finasteride after chronic incomplete spinal cord injury—a randomized, double-blind, and placebo-controlled pilot study Open
Background High-dose testosterone replacement therapy (TRT), paired with finasteride (type II 5α-reductase inhibitor), improves body composition, muscle strength, and bone mineral density (BMD) in older men, without inducing prostate enlar…
View article: Diet Quality of Stroke Survivors Versus Neurologically Intact US Adults
Diet Quality of Stroke Survivors Versus Neurologically Intact US Adults Open
Stroke is a leading cause of disability in the US, often altering one’s ability to access and consume food. The aim of the present study was to characterize and evaluate predictors of stroke survivors’ diet quality (DQ). A cross-sectional …
View article: Drop Vertical Jump Landing Mechanics Are Similar Between Patients With Quadriceps Tendon and Patellar Tendon Autografts After Anterior Cruciate Ligament Reconstruction
Drop Vertical Jump Landing Mechanics Are Similar Between Patients With Quadriceps Tendon and Patellar Tendon Autografts After Anterior Cruciate Ligament Reconstruction Open
Level III, retrospective comparative study.
View article: Diet Quality Predictors of Physical Function, Activity, and Psychosocial Health Among Individuals With a History of Stroke
Diet Quality Predictors of Physical Function, Activity, and Psychosocial Health Among Individuals With a History of Stroke Open
Objectives: Stroke is a leading cause of disability in the US, often altering one's physical function, activity, and psychosocial health. Ability to access and consume food may also be limited following stroke, impacting diet quality (DQ).…
View article: Association of Brain Age, Lesion Volume, and Functional Outcome in Patients With Stroke
Association of Brain Age, Lesion Volume, and Functional Outcome in Patients With Stroke Open
We provide evidence that younger brain age is associated with superior poststroke outcomes and modifies the impact of focal damage. The inclusion of imaging-based assessments of brain age and brain resilience may improve the prediction of …
View article: Interhemispheric Asymmetries in Intracortical Facilitation Correlate With Fatigue Severity in Individuals With Poststroke Fatigue
Interhemispheric Asymmetries in Intracortical Facilitation Correlate With Fatigue Severity in Individuals With Poststroke Fatigue Open
Purpose: Poststroke fatigue (PSF) contributes to increased mortality and reduces participation in rehabilitative therapy. Although PSF's negative influences are well known, there are currently no effective evidence-based treatments for PSF…
View article: Feasibility of performing a multi-arm clinical trial examining the novel combination of repetitive transcranial magnetic stimulation and aerobic exercise for post-stroke depression
Feasibility of performing a multi-arm clinical trial examining the novel combination of repetitive transcranial magnetic stimulation and aerobic exercise for post-stroke depression Open
Performing a multi-arm combinatorial trial examining the effect of rTMS+AEx on PSD appears feasible. All treatment arms demonstrated strong adherence to their respective interventions and were well received. rTMS and the combination of AEx…
View article: Combined Aerobic Exercise and Virtual Reality-Based Upper Extremity Rehabilitation Intervention for Chronic Stroke: Feasibility and Preliminary Effects on Physical Function and Quality of Life
Combined Aerobic Exercise and Virtual Reality-Based Upper Extremity Rehabilitation Intervention for Chronic Stroke: Feasibility and Preliminary Effects on Physical Function and Quality of Life Open
Combining lower extremity AEx and VR-UE rehabilitation appears feasible in the clinical research setting. Fifteen minutes of lower extremity AEx performed at vigorous intensity appears to elicit clinically meaningful benefits in chronic st…
View article: The relationship between motor pathway damage and flexion-extension patterns of muscle co-excitation during walking
The relationship between motor pathway damage and flexion-extension patterns of muscle co-excitation during walking Open
Background Mass flexion-extension co-excitation patterns during walking are often seen as a consequence of stroke, but there is limited understanding of the specific contributions of different descending motor pathways toward their control…
View article: Priming Upper Extremity Motor Practice With Aerobic Exercise (PUMP-Ex): A Preliminary Report on Feasibility and Efficacy
Priming Upper Extremity Motor Practice With Aerobic Exercise (PUMP-Ex): A Preliminary Report on Feasibility and Efficacy Open
Date Presented 04/02/2022 Stroke often leaves survivors with lasting upper extremity (UE) motor impairments. To influence recovery, the brain must be plastic, or moldable, to allow change, and rehabilitation must be individualized and prog…
View article: A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms
A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms Open
Accurate lesion segmentation is critical in stroke rehabilitation research for the quantification of lesion burden and accurate image processing. Current automated lesion segmentation methods for T1-weighted (T1w) MRIs, commonly used in st…
View article: Global brain health modulates the impact of lesion damage on post-stroke sensorimotor outcomes
Global brain health modulates the impact of lesion damage on post-stroke sensorimotor outcomes Open
Sensorimotor performance after stroke is strongly related to focal injury measures such as corticospinal tract lesion load. However, the role of global brain health is less clear. Here, we examined the impact of brain age, a measure of neu…
View article: A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms
A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms Open
Accurate lesion segmentation is critical in stroke rehabilitation research for the quantification of lesion burden and accurate image processing. Current automated lesion segmentation methods for T1-weighted (T1w) MRIs, commonly used in re…
View article: Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide
Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide Open
Up to two-thirds of stroke survivors experience persistent sensorimotor impairments. Recovery relies on the integrity of spared brain areas to compensate for damaged tissue. Deep grey matter structures play a critical role in the control a…
View article: Contributions of social determinants of health to systolic blood pressure in United States adult immigrants: Use of path analysis to validate a conceptual framework
Contributions of social determinants of health to systolic blood pressure in United States adult immigrants: Use of path analysis to validate a conceptual framework Open
Objective Validate a conceptual framework and identify pathways between antecedent (life-course socioeconomic status (L-SES)), predisposing (age, sex, married, homeless as a child), enabling (health literacy, acculturation), and need (disa…
View article: Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide
Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide Open
Background and Purpose Up to two-thirds of stroke survivors experience persistent sensorimotor impairments. Recovery relies on the integrity of spared brain areas to compensate for damaged tissue. Subcortical regions play critical roles in…
View article: Evaluating a novel <scp>MR‐compatible</scp> foot pedal device for unipedal and bipedal motion: <scp>Test–retest</scp> reliability of evoked brain activity
Evaluating a novel <span>MR‐compatible</span> foot pedal device for unipedal and bipedal motion: <span>Test–retest</span> reliability of evoked brain activity Open
The purpose of this study was to develop and evaluate a new, open‐source MR‐compatible device capable of assessing unipedal and bipedal lower extremity movement with minimal head motion and high test–retest reliability. To evaluate the pro…
View article: The <scp>ENIGMA</scp> Stroke Recovery Working Group: Big data neuroimaging to study brain–behavior relationships after stroke
The <span>ENIGMA</span> Stroke Recovery Working Group: Big data neuroimaging to study brain–behavior relationships after stroke Open
The goal of the Enhancing Neuroimaging Genetics through Meta‐Analysis (ENIGMA) Stroke Recovery working group is to understand brain and behavior relationships using well‐powered meta‐ and mega‐analytic approaches. ENIGMA Stroke Recovery ha…
View article: Associations Between Doing Planned Exercise and Probable Major Depressive Disorder in Individuals Following Spinal Cord Injury
Associations Between Doing Planned Exercise and Probable Major Depressive Disorder in Individuals Following Spinal Cord Injury Open
Background: In neurologically healthy individuals, exercise positively impacts depressive symptoms, but there is limited knowledge regarding the association between exercise behaviors and depression after spinal cord injury (SCI). Objectiv…