Chris J. Wright
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View article: A Deep Learning Model of Lightning Stroke Density
A Deep Learning Model of Lightning Stroke Density Open
Lightning plays a crucial role in the Earth's climate system, yet existing parameterizations for use in forecasting and earth system models show room for improvement in capturing spatial and temporal variations in its frequency. This study…
View article: Graded porous scaffold mediates internal fluidic environment for 3D in vitro mechanobiology
Graded porous scaffold mediates internal fluidic environment for 3D in vitro mechanobiology Open
Most cell types are mechanosensitive, their activities such as differentiation, proliferation and apoptosis, can be influenced by the mechanical environment through mechanical stimulation. In three dimensional (3D) mechanobiological in vit…
View article: Lightning declines over shipping lanes following regulation of fuel sulfur emissions
Lightning declines over shipping lanes following regulation of fuel sulfur emissions Open
Aerosol interactions with clouds represent a significant uncertainty in our understanding of the Earth system. Deep convective clouds may respond to aerosol perturbations in several ways that have proven difficult to elucidate with observa…
View article: 1205 Surmounting conventional cell therapy limitations<i> via in situ</i> CAR therapy using oRNA™ lipid nanoparticles
1205 Surmounting conventional cell therapy limitations<i> via in situ</i> CAR therapy using oRNA™ lipid nanoparticles Open
Background Ex vivo generated chimeric antigen receptor (CAR) T cell therapies have shown tremendous success in treating hematologic malignancies. However, this modality has significant limitations to providing treatment to a broader popula…
View article: Mechanical environment for <i>in vitro</i> cartilage tissue engineering assisted by <i>in silico</i> models.
Mechanical environment for <i>in vitro</i> cartilage tissue engineering assisted by <i>in silico</i> models. Open
Mechanobiological study of chondrogenic cells and multipotent stem cells for articular cartilage tissue engineering (CTE) has been widely explored. The mechanical stimulation in terms of wall shear stress, hydrostatic pressure and mechanic…
View article: Adherence to the Standards for Reporting of Diagnostic Accuracy (STARD) 2015 Guidelines in Acute Point-of-Care Ultrasound Research
Adherence to the Standards for Reporting of Diagnostic Accuracy (STARD) 2015 Guidelines in Acute Point-of-Care Ultrasound Research Open
Overall, the literature on acute care point-of-care ultrasound showed moderate adherence to the STARD 2015 guidelines, with more complete reporting found in studies citing STARD and those published in STARD-adopting journals. This study ha…
View article: Exploring the current state of play for cost-effective water treatment by membranes
Exploring the current state of play for cost-effective water treatment by membranes Open
This article presents a perspective on the current development and application of membranes for the treatment of water. We examine how membranes contribute to the global challenge of sustainable supply of clean water. The main theme is on …
View article: Electrospinning of Functional Nanofibers for Regenerative Medicine: From Bench to Commercial Scale
Electrospinning of Functional Nanofibers for Regenerative Medicine: From Bench to Commercial Scale Open
Nanofibers are an important material for regenerative medicine as they have a commensurate morphology to that of the macromolecular matrix that supports and houses the growth of cells and tissues within the body. Electrospinning is widely …
View article: Control of collagen gel mechanical properties through manipulation of gelation conditions near the sol–gel transition
Control of collagen gel mechanical properties through manipulation of gelation conditions near the sol–gel transition Open
It is shown herein that it is possible to control the mechanical and microstructural properties of collagen gels by manipulating temperature in the vicinity of the sol–gel transition; the Fractional Maxwell Model is also shown to accuratel…
View article: <i>In vivo</i> comparison of jellyfish and bovine collagen sponges as prototype medical devices
<i>In vivo</i> comparison of jellyfish and bovine collagen sponges as prototype medical devices Open
Jellyfish have emerged as a source of next generation collagen that is an attractive alternative to existing sources, such as bovine and porcine, due to a plentiful supply and providing a safer source through lack of bovine spongiform ence…
View article: The fabrication of iron oxide nanoparticle‐nanofiber composites by electrospinning and their applications in tissue engineering
The fabrication of iron oxide nanoparticle‐nanofiber composites by electrospinning and their applications in tissue engineering Open
This paper reviews the use of iron oxide nanoparticle‐nanofiber composites in tissue engineering with a focus on the electrospinning technique. Electrospinning is an established method of scaffold fabrication offering a number of key advan…
View article: Atomic Force Microscopy of Biofilms—Imaging, Interactions, and Mechanics
Atomic Force Microscopy of Biofilms—Imaging, Interactions, and Mechanics Open
Atomic force microscopy (AFM) has proven itself to be a powerful and diverse tool for the study of microbial systems on both single and multicellular scales including complex biofilms. This chapter will review how AFM and its derivatives h…