Chris L. McGowin
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View article: Summary of the Fourth Annual American Sexually Transmitted Diseases Association Workshop on Improving Sexually Transmitted Infection Control Efforts Through Cross-Sector Collaboration
Summary of the Fourth Annual American Sexually Transmitted Diseases Association Workshop on Improving Sexually Transmitted Infection Control Efforts Through Cross-Sector Collaboration Open
The American Sexually Transmitted Diseases Association has, for several years, been conducting a cross-sector workshop to bring together a variety of stakeholders to develop ideas for collaboratively improving the sexually transmitted infe…
View article: Trichomonas vaginalis Detection in Urogenital Specimens from Symptomatic and Asymptomatic Men and Women by Use of the cobas TV/MG Test
Trichomonas vaginalis Detection in Urogenital Specimens from Symptomatic and Asymptomatic Men and Women by Use of the cobas TV/MG Test Open
Trichomonas vaginalis is a prevalent sexually transmitted infection (STI). Diagnosis has historically relied on either microscopic analysis or culture, the latter being the previous gold standard.
View article: 416. Comparative Analytical Assessment of PCR Mastermixes for Detection of SARS-CoV-2 using the CDC Diagnostic Test and the LightMix Modular Test on the cobas® z 480 Analyzer
416. Comparative Analytical Assessment of PCR Mastermixes for Detection of SARS-CoV-2 using the CDC Diagnostic Test and the LightMix Modular Test on the cobas® z 480 Analyzer Open
Background The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a betacoronavirus responsible for the ongoing global pandemic and associated respiratory disease. Rapid development and implementation of molecular diagno…
View article: Mycoplasma genitalium Detection in Urogenital Specimens from Symptomatic and Asymptomatic Men and Women by Use of the cobas TV/MG Test
Mycoplasma genitalium Detection in Urogenital Specimens from Symptomatic and Asymptomatic Men and Women by Use of the cobas TV/MG Test Open
Mycoplasma genitalium (MG) infections are a growing concern within the field of sexually transmitted infections. However, diagnostic assays for M. genitalium have been limited in the United States. As most infections are asymptomatic, indi…
View article: 432. Qualitative Differentiation of Genital Ulcer Disease Etiology via Nucleic Acid Amplification Testing (NAAT)
432. Qualitative Differentiation of Genital Ulcer Disease Etiology via Nucleic Acid Amplification Testing (NAAT) Open
Background Genital ulcers (GUs) remain a common reason that both men and women seek treatment at US sexual health clinics. Presumptive diagnosis based solely on the macroscopic lesion characteristics is insensitive for differentiating betw…
View article: P033 Differentiation of common genital ulcer disease pathogens using sequential or parallel molecular testing
P033 Differentiation of common genital ulcer disease pathogens using sequential or parallel molecular testing Open
Background The most common infectious etiologies of genital ulcers (GUs) in the USA are Herpes Simplex Virus infections (HSV1/2) and Treponema pallidum (Syphilis). GUs are a common symptom reported by men and women attending US sexu…
View article: Prevalence and cervical organism burden among Louisiana women with Trichomonas vaginalis infections
Prevalence and cervical organism burden among Louisiana women with Trichomonas vaginalis infections Open
Trichomonas vaginalis is the most common curable sexually transmitted infection (STI) worldwide. Although predominately asymptomatic, the disease spectrum of trichomoniasis in women is characterized primarily by signs and symptoms of vagin…
View article: A novel whole-bacterial enzyme linked-immunosorbant assay to quantify Chlamydia trachomatis specific antibodies reveals distinct differences between systemic and genital compartments
A novel whole-bacterial enzyme linked-immunosorbant assay to quantify Chlamydia trachomatis specific antibodies reveals distinct differences between systemic and genital compartments Open
Chlamydia trachomatis (CT) is the leading sexually transmitted bacterial infection. The continued global burden of CT infection strongly predicates the need for a vaccine to supplement current chlamydial control programs. The correlates of…
View article: The Unique Microbiology and Molecular Pathogenesis of Mycoplasma genitalium
The Unique Microbiology and Molecular Pathogenesis of Mycoplasma genitalium Open
Mycoplasma genitalium is increasingly appreciated as a common cause of sexually transmitted disease syndromes, including urethritis in men and cervicitis, endometritis, pelvic inflammatory disease, and possibly preterm birth, tubal factor …
View article: Histological Evidence of Chronic<i>Mycoplasma genitalium</i>–Induced Cervicitis in HIV-Infected Women: A Retrospective Cohort Study
Histological Evidence of Chronic<i>Mycoplasma genitalium</i>–Induced Cervicitis in HIV-Infected Women: A Retrospective Cohort Study Open
These findings implicate M. genitalium as an etiologic agent of cervicitis in HIV-infected women, providing a potential mechanism for enhanced HIV transmission to an uninfected partner. Screening and treatment of M. genitalium among HIV-in…
View article: Chlamydia trachomatis Infection of Endocervical Epithelial Cells Enhances Early HIV Transmission Events
Chlamydia trachomatis Infection of Endocervical Epithelial Cells Enhances Early HIV Transmission Events Open
Chlamydia trachomatis causes a predominantly asymptomatic, but generally inflammatory, genital infection that is associated with an increased risk for HIV acquisition. Endocervical epithelial cells provide the major niche for this obligate…