Chris Lindensmith
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View article: Extant life detection using label-free video microscopy in analog aquatic environments
Extant life detection using label-free video microscopy in analog aquatic environments Open
The ability of microbial active motion, morphology, and optical properties to serve as biosignatures was investigated by in situ video microscopy in a wide range of extreme field sites where such imaging had not been performed previously. …
View article: Onboard Science Instrument Autonomy for the Detection of MicroscopyBiosignatures on the Ocean Worlds Life Surveyor
Onboard Science Instrument Autonomy for the Detection of MicroscopyBiosignatures on the Ocean Worlds Life Surveyor Open
The quest to find extraterrestrial life is a critical scientific endeavor with civilization-level implications. Icy moons in our solar system are promising targets for exploration because their liquid oceans make them potential habitats fo…
View article: Onboard Science Instrument Autonomy for the Detection of Microscopy Biosignatures on the Ocean Worlds Life Surveyor
Onboard Science Instrument Autonomy for the Detection of Microscopy Biosignatures on the Ocean Worlds Life Surveyor Open
The quest to find extraterrestrial life is a critical scientific endeavor with civilization-level implications. Icy moons in our solar system are promising targets for exploration because their liquid oceans make them potential habitats fo…
View article: A multi-modal volumetric microscope with automated sample handling for surveying microbial life in liquid samples
A multi-modal volumetric microscope with automated sample handling for surveying microbial life in liquid samples Open
In the study of microbial life, microscopy plays a unique role due to its ability to detect ordered structure, motility, and fluorescence signals. As such it has also recently gained attention in the context of searching for extant life on…
View article: Using the Gouy phase anomaly to localize and track bacteria in digital holographic microscopy 4D images
Using the Gouy phase anomaly to localize and track bacteria in digital holographic microscopy 4D images Open
Described over 100 years ago, the Gouy phase anomaly refers to the additional phase shift that is accumulated as a wave passes through focus. It is potentially useful in analyzing any type of phase-sensitive imaging; in light microscopy,…
View article: Key Technologies for the Wide Field Infrared Survey Telescope Coronagraph Instrument
Key Technologies for the Wide Field Infrared Survey Telescope Coronagraph Instrument Open
The Wide Field Infrared Survey Telescope (WFIRST) Coronagraph Instrument (CGI) is a high-contrast imager and integral field spectrograph that will enable the study of exoplanets and circumstellar disks at visible wavelengths. Ground-based …
View article: Key Technologies for the Wide Field Infrared Survey Telescope Coronagraph Instrument
Key Technologies for the Wide Field Infrared Survey Telescope Coronagraph Instrument Open
The Wide Field Infrared Survey Telescope (WFIRST) Coronagraph Instrument (CGI) is a high-contrast imager and integral field spectrograph that will enable the study of exoplanets and circumstellar disks at visible wavelengths. Ground-based …
View article: Development and qualification of a fiber optic cable for Martian environments
Development and qualification of a fiber optic cable for Martian environments Open
ChemCam is an instrument suite on the Mars Science Laboratory (MSL) mission that will launch to Mars in 2011. MSL is a rover-type lander that is capable of exploring large territories over the mission lifetime and includes a number of inst…
View article: Digital Holographic Microscopy, a Method for Detection of Microorganisms in Plume Samples from Enceladus and Other Icy Worlds
Digital Holographic Microscopy, a Method for Detection of Microorganisms in Plume Samples from Enceladus and Other Icy Worlds Open
Detection of extant microbial life on Earth and elsewhere in the Solar System requires the ability to identify and enumerate micrometer-scale, essentially featureless cells. On Earth, bacteria are usually enumerated by culture plating or e…
View article: Sources and propagation of errors in quantitative phase imaging techniques using optical interferometry
Sources and propagation of errors in quantitative phase imaging techniques using optical interferometry Open
Quantitative phase imaging (QPI) has many applications in a broad range of disciplines from astronomy to microbiology. QPI is often performed by optical interferometry, where two coherent beams of light are used to produce interference pat…
View article: Compact, lensless digital holographic microscope for remote microbiology
Compact, lensless digital holographic microscope for remote microbiology Open
In situ investigation of microbial life in extreme environments can be carried out with microscopes capable of imaging 3-dimensional volumes and tracking particle motion. Here we present a lensless digital holographic microscope approach t…
View article: Microbial Morphology and Motility as Biosignatures for Outer Planet Missions
Microbial Morphology and Motility as Biosignatures for Outer Planet Missions Open
Meaningful motion is an unambiguous biosignature, but because life in the Solar System is most likely to be microbial, the question is whether such motion may be detected effectively on the micrometer scale. Recent results on microbial mot…