Christopher Hartley
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View article: Spatial Conformation of Pancreatic Cancer Is Associated with Disease Recurrence after Curative-Intent Total Neoadjuvant Therapy
Spatial Conformation of Pancreatic Cancer Is Associated with Disease Recurrence after Curative-Intent Total Neoadjuvant Therapy Open
Pancreatic ductal adenocarcinoma (PDAC) frequently recurs after total neoadjuvant therapy (TNT) and curative-intent resection. Traditional histopathologic response assessments demonstrate that major pathologic response (<5-10% viable resid…
View article: Assessing Risk of Progression in Barrett's Esophagus Using a Mass-Spectrometry-Based Proteomic Panel
Assessing Risk of Progression in Barrett's Esophagus Using a Mass-Spectrometry-Based Proteomic Panel Open
INTRODUCTION: Esophageal adenocarcinoma (EAC) is an aggressive cancer with poor prognosis. Barrett's esophagus (BE) is a critical precursor of EAC. Patients with BE undergo endoscopic surveillance to monitor disease progression although on…
View article: Corneal Ulcers: The Most Common Eye Condition Among Dogs in Sri Lanka
Corneal Ulcers: The Most Common Eye Condition Among Dogs in Sri Lanka Open
This study was aimed to investigate the incidence of corneal ulcers (CU) in dogs focusing on breed, age, gender, affected eye, type of ulcer, location of ulcer, and identifying common causes for formation of CU. A complete ophthalmic exami…
View article: Corneal Ulcers: The Most Common Eye Condition Among Dogs in Sri Lanka
Corneal Ulcers: The Most Common Eye Condition Among Dogs in Sri Lanka Open
This study was aimed to investigate the incidence of corneal ulcers (CU) in dogs focusing on breed, age, gender, affected eye, type of ulcer, location of ulcer, and identifying common causes for formation of CU. A complete ophthalmic exami…
View article: Predicting the Risk of Progression from Barrett’s Esophagus to Esophageal Adenocarcinoma with a Mass-Spectrometry-Based Proteomic Panel
Predicting the Risk of Progression from Barrett’s Esophagus to Esophageal Adenocarcinoma with a Mass-Spectrometry-Based Proteomic Panel Open
Background Esophageal adenocarcinoma (EAC) is a highly aggressive cancer with poor prognosis, often arising from gastroesophageal reflux disease (GERD) and its precursor, Barrett’s esophagus (BE). Although only a small proportion of indivi…
View article: Utilization of an artificial intelligence–enhanced, web‐based application to review bile duct brushing cytologic specimens: A pilot study
Utilization of an artificial intelligence–enhanced, web‐based application to review bile duct brushing cytologic specimens: A pilot study Open
Background The authors previously developed an artificial intelligence (AI) to assist cytologists in the evaluation of digital whole‐slide images (WSIs) generated from bile duct brushing specimens. The aim of this trial was to assess the e…
View article: Supplementary Figure S1 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Figure S1 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Figure S1. Flow diagram outlining the steps undertaken in this study.
View article: Supplementary Table S2 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Table S2 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Table S2. Concordance between ASCO and QuantCRC-Integrated risk groups
View article: Supplementary Figure S2 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Figure S2 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Figure S2. Scatter plots of QuantCRC features stratified by QuantCRC-integrated and ASCO risk schemes.
View article: Supplementary Table S1 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Table S1 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Table S1. Univariate and multivariate analysis of QuantCRC risk classification, pT stage, and any high-risk pathologic feature.
View article: Supplementary Table S5 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Table S5 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Table S5. Adjuvant chemotherapy according to ASCO and QuantCRC-Integrated risk groups.
View article: Supplementary Table S4 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Table S4 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Table S4. Clinical and Pathologic features in patients that were concordant or discordant in the ASCO and QuantCRC-Integrated schemes.
View article: Supplementary Table S3 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Table S3 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Table S3. Carcinoembryonic antigen levels according to ASCO and QuantCRC-Integrated risk groups.
View article: Data from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Data from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Purpose:There is a need to improve current risk stratification of stage II colorectal cancer to better inform risk of recurrence and guide adjuvant chemotherapy. We sought to examine whether integration of QuantCRC, a digital pathology bio…
View article: Supplementary Table S3 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Table S3 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Table S3. Carcinoembryonic antigen levels according to ASCO and QuantCRC-Integrated risk groups.
View article: Supplementary Table S5 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Table S5 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Table S5. Adjuvant chemotherapy according to ASCO and QuantCRC-Integrated risk groups.
View article: Supplementary Table S1 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Table S1 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Table S1. Univariate and multivariate analysis of QuantCRC risk classification, pT stage, and any high-risk pathologic feature.
View article: Data from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Data from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Purpose:There is a need to improve current risk stratification of stage II colorectal cancer to better inform risk of recurrence and guide adjuvant chemotherapy. We sought to examine whether integration of QuantCRC, a digital pathology bio…
View article: Supplementary Figure S2 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Figure S2 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Figure S2. Scatter plots of QuantCRC features stratified by QuantCRC-integrated and ASCO risk schemes.
View article: Supplementary Table S4 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Table S4 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Table S4. Clinical and Pathologic features in patients that were concordant or discordant in the ASCO and QuantCRC-Integrated schemes.
View article: Supplementary Figure S1 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Figure S1 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Figure S1. Flow diagram outlining the steps undertaken in this study.
View article: Supplementary Table S2 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Supplementary Table S2 from Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Supplementary Table S2. Concordance between ASCO and QuantCRC-Integrated risk groups
View article: Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC
Improved Risk-Stratification Scheme for Mismatch-Repair Proficient Stage II Colorectal Cancers Using the Digital Pathology Biomarker QuantCRC Open
Purpose: There is a need to improve current risk stratification of stage II colorectal cancer to better inform risk of recurrence and guide adjuvant chemotherapy. We sought to examine whether integration of QuantCRC, a digital pathology bi…
View article: Evaluation of automated sample preparation system for lymph node sampling
Evaluation of automated sample preparation system for lymph node sampling Open
Study results suggest that slides prepared by the automated system are of adequate quality for adequacy assessment with diagnostic concordance when compared to SOC slides.