Chris Press
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View article: Self-amplifying RNA-based activation of HIV-1 broadly neutralizing antibody B cell precursors 2690
Self-amplifying RNA-based activation of HIV-1 broadly neutralizing antibody B cell precursors 2690 Open
Description Elicitation of broadly HIV neutralizing antibody (Ab) responses requires sequential immunizations with specifically designed HIV Env-derived proteins. Such constructs are presently in pre-clinical and clinical evaluation, but t…
View article: Lyophilization process engineering and thermostability of ID93 + GLA-SE, a single-vial adjuvanted subunit tuberculosis vaccine candidate for use in clinical studies
Lyophilization process engineering and thermostability of ID93 + GLA-SE, a single-vial adjuvanted subunit tuberculosis vaccine candidate for use in clinical studies Open
Promising clinical efficacy results have generated considerable enthusiasm for the potential impact of adjuvant-containing subunit tuberculosis vaccines. The development of a thermostable tuberculosis vaccine formulation could have signifi…
View article: Development and Testing of a Spray-Dried Tuberculosis Vaccine Candidate in a Mouse Model
Development and Testing of a Spray-Dried Tuberculosis Vaccine Candidate in a Mouse Model Open
Converting a vaccine into a thermostable dry powder is advantageous as it reduces the resource burden linked with the cold chain and provides flexibility in dosage and administration through different routes. Such a dry powder presentation…