Chris R. Taitt
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View article: Impact of template denaturation prior to whole genome amplification on gene detection in high GC-content species, Burkholderia mallei and B. pseudomallei
Impact of template denaturation prior to whole genome amplification on gene detection in high GC-content species, Burkholderia mallei and B. pseudomallei Open
View article: Machine learning for design of degenerate Cas13a crRNAs using lassa virus as a model of highly variable RNA target
Machine learning for design of degenerate Cas13a crRNAs using lassa virus as a model of highly variable RNA target Open
View article: Prevalence of malaria resistance-associated mutations in Plasmodium falciparum circulating in 2017–2018, Bo, Sierra Leone
Prevalence of malaria resistance-associated mutations in Plasmodium falciparum circulating in 2017–2018, Bo, Sierra Leone Open
Introduction In spite of promising medical, sociological, and engineering strategies and interventions to reduce the burden of disease, malaria remains a source of significant morbidity and mortality, especially among children in sub-Sahar…
View article: Comparative analysis of stalked and acorn barnacle adhesive proteomes
Comparative analysis of stalked and acorn barnacle adhesive proteomes Open
Barnacles interest the scientific community for multiple reasons: their unique evolutionary trajectory, vast diversity and economic impact—as a harvested food source and also as one of the most prolific macroscopic hard biofouling organism…
View article: Comparison of capillary and venous blood for malaria detection using two PCR-based assays in febrile patients in Sierra Leone
Comparison of capillary and venous blood for malaria detection using two PCR-based assays in febrile patients in Sierra Leone Open
View article: Comparison of capillary and venous blood for malaria detection using two PCR based assays in febrile patients in Sierra Leone.
Comparison of capillary and venous blood for malaria detection using two PCR based assays in febrile patients in Sierra Leone. Open
Background. Rapid and sensitive diagnostics are critical tools for clinical case management and public health control efforts. Both capillary and venous blood are currently used for malaria detection and while diagnostic technologies may n…
View article: Supplemental File 4. from Comparative analysis of stalked and acorn barnacle adhesive proteomes
Supplemental File 4. from Comparative analysis of stalked and acorn barnacle adhesive proteomes Open
Proteomics results for A. amphitrite adhesive samples analyzed on the Thermo Orbitrap with the NRL transcriptome-based predicted proteome.
View article: Supplemental File 5. from Comparative analysis of stalked and acorn barnacle adhesive proteomes
Supplemental File 5. from Comparative analysis of stalked and acorn barnacle adhesive proteomes Open
Proteomics results for A. amphitrite adhesive samples analyzed on the Thermo Orbitrap with the SNU_Aamp and NRL transcriptome-based predicted proteomes.
View article: Supplemental File 3. from Comparative analysis of stalked and acorn barnacle adhesive proteomes
Supplemental File 3. from Comparative analysis of stalked and acorn barnacle adhesive proteomes Open
Proteomics results for A. amphitrite adhesive samples analyzed on the Thermo Orbitrap with the SNU_Aamp predicted proteome.
View article: Supplemental File 6. from Comparative analysis of stalked and acorn barnacle adhesive proteomes
Supplemental File 6. from Comparative analysis of stalked and acorn barnacle adhesive proteomes Open
Proteomics results for P. pollicipes adhesive samples analyzed on the Thermo Orbitrap with the Ppol_2 predicted proteome.
View article: <i>Escherichia coli</i> as a Potential Reservoir of Antimicrobial Resistance Genes on the Island of O'ahu.
<i>Escherichia coli</i> as a Potential Reservoir of Antimicrobial Resistance Genes on the Island of O'ahu. Open
The problem of antimicrobial-resistant bacteria has not been adequately explored in the tropical island environment. To date, there has not been a systematic investigation into the prevalence and distribution of antimicrobial resistance de…
View article: Supplemental File 1. from Comparative analysis of stalked and acorn barnacle adhesive proteomes
Supplemental File 1. from Comparative analysis of stalked and acorn barnacle adhesive proteomes Open
Contains Supplemental Tables 1-5. Supplemental Table 1: BLASTp results for the NRL transcriptome-based database compared to the SNU_Aamp predicted proteome. Supplemental Table 2: BLASTp results for the A. amphitrite…
View article: Supplemental File 2. from Comparative analysis of stalked and acorn barnacle adhesive proteomes
Supplemental File 2. from Comparative analysis of stalked and acorn barnacle adhesive proteomes Open
Proteomics results for A. amphitrite adhesive samples analyzed on the Sciex 5500 with the SNU_Aamp predicted proteome.
View article: Comparison of capillary and venous blood for malaria detection using two PCR based assays in febrile patients in Sierra Leone.
Comparison of capillary and venous blood for malaria detection using two PCR based assays in febrile patients in Sierra Leone. Open
Background. Malaria parasites infect over 200 million people and cause more than 400,000 deaths each year. Rapid and sensitive diagnostics are critical tools for clinical case management and public health control efforts. Both capillary an…
View article: Distribution of Select Cement Proteins in the Acorn Barnacle Amphibalanus amphitrite
Distribution of Select Cement Proteins in the Acorn Barnacle Amphibalanus amphitrite Open
Acorn barnacles are major marine fouling organisms. Their success is largely due to an ability to adhere to diverse substrates via a sub-micron thick proteinaceous adhesive layer that develops as the organism molts and expands its base. Re…
View article: Tracking Antimicrobial Resistance Determinants in Diarrheal Pathogens: A Cross-Institutional Pilot Study
Tracking Antimicrobial Resistance Determinants in Diarrheal Pathogens: A Cross-Institutional Pilot Study Open
Infectious diarrhea affects over four billion individuals annually and causes over a million deaths each year. Though not typically prescribed for treatment of uncomplicated diarrheal disease, antimicrobials serve as a critical part of the…
View article: A Survey of Antimicrobial Resistance Determinants in Category A Select Agents, Exempt Strains, and Near-Neighbor Species
A Survey of Antimicrobial Resistance Determinants in Category A Select Agents, Exempt Strains, and Near-Neighbor Species Open
A dramatic increase in global antimicrobial resistance (AMR) has been well documented. Of particular concern is the dearth of information regarding the spectrum and prevalence of AMR within Category A Select Agents. Here, we performed a su…
View article: Use of real-time multiplex PCR, malaria rapid diagnostic test and microscopy to investigate the prevalence of Plasmodium species among febrile hospital patients in Sierra Leone
Use of real-time multiplex PCR, malaria rapid diagnostic test and microscopy to investigate the prevalence of Plasmodium species among febrile hospital patients in Sierra Leone Open
Background Malaria continues to affect over 200 million individuals every year, especially children in Africa. Rapid and sensitive detection and identification of Plasmodium parasites is crucial for treating patients and monitoring of cont…
View article: Comparison of capillary and venous blood for malaria detection using two PCR based assays in febrile patients in Sierra Leone.
Comparison of capillary and venous blood for malaria detection using two PCR based assays in febrile patients in Sierra Leone. Open
Background Malaria parasites infect over 200 million people and cause more than 400,000 deaths each year. Rapid and sensitive diagnostics are critical tools for clinical case management and public health control efforts. Both capillary and…
View article: Characterization of longitudinal canal tissue in the acorn barnacle Amphibalanus amphitrite
Characterization of longitudinal canal tissue in the acorn barnacle Amphibalanus amphitrite Open
The morphology and composition of tissue located within parietal shell canals of the barnacle Amphibalanus amphitrite are described. Longitudinal canal tissue nearly spans the length of side shell plates, terminating near the leading edge …
View article: Rapid design and fielding of four diagnostic technologies in Sierra Leone, Thailand, Peru, and Australia: Successes and challenges faced introducing these biosensors
Rapid design and fielding of four diagnostic technologies in Sierra Leone, Thailand, Peru, and Australia: Successes and challenges faced introducing these biosensors Open
Febrile illnesses are among the most common reasons for visits to hospitals and clinics worldwide. Since fevers can arise from a wide range of diseases, identifying the causative pathogen is essential not only for effective personal treatm…
View article: Seroprevalence of hepatitis B surface antigen (HBsAg) in Bo, Sierra Leone, 2012–2013
Seroprevalence of hepatitis B surface antigen (HBsAg) in Bo, Sierra Leone, 2012–2013 Open
View article: Analytical Chemistry for Homeland Defense and National Security
Analytical Chemistry for Homeland Defense and National Security Open
The budget was requested to support speaker expenses to attend and speak in the day long symposium at the ACS meeting. The purpose of the symposium was to encourage analytical chemists to contribute to national security.
View article: Prevalence of markers of HIV infection among febrile adults and children in Bo, Sierra Leone, 2012–2013
Prevalence of markers of HIV infection among febrile adults and children in Bo, Sierra Leone, 2012–2013 Open
View article: Surveillance of Vector-Borne Infections (Chikungunya, Dengue, and Malaria) in Bo, Sierra Leone, 2012–2013
Surveillance of Vector-Borne Infections (Chikungunya, Dengue, and Malaria) in Bo, Sierra Leone, 2012–2013 Open
Malaria remains a significant cause of morbidity and mortality in West Africa, but the contribution of other vector-borne infections (VBIs) to the burden of disease has been understudied. We used rapid diagnostic tests (RDTs) for three VBI…
View article: Antimicrobial resistance of Klebsiella pneumoniae stool isolates circulating in Kenya
Antimicrobial resistance of Klebsiella pneumoniae stool isolates circulating in Kenya Open
We sought to determine the genetic and phenotypic antimicrobial resistance (AMR) profiles of commensal Klebsiella spp. circulating in Kenya by testing human stool isolates of 87 K. pneumoniae and three K. oxytoca collected at eight locatio…
View article: POINT-OF-NEED DIAGNOSTICS: BIOSURVEILLANCE WITH A DEVICE2CLOUD CAPABILITY IN SIERRA LEONE
POINT-OF-NEED DIAGNOSTICS: BIOSURVEILLANCE WITH A DEVICE2CLOUD CAPABILITY IN SIERRA LEONE Open
Background Infectious diseases contribute to a high burden of diseases globally. Surveillance using low-cost technology, combined with cutting edge platforms offers a path for understanding the disease ecology of locations of interest in r…
View article: Finished Genome Sequence of the Highly Multidrug-Resistant Human Urine Isolate Citrobacter freundii Strain SL151
Finished Genome Sequence of the Highly Multidrug-Resistant Human Urine Isolate Citrobacter freundii Strain SL151 Open
Citrobacter freundii is a Gram-negative opportunistic pathogen that is increasingly being recognized as a causative agent of hospital-acquired urinary tract infections and an important reservoir of antimicrobial resistance determinants. In…
View article: Prevalence of Quinolone Resistance in Enterobacteriaceae from Sierra Leone and the Detection of <i>qnrB</i> Pseudogenes and Modified LexA Binding Sites
Prevalence of Quinolone Resistance in Enterobacteriaceae from Sierra Leone and the Detection of <i>qnrB</i> Pseudogenes and Modified LexA Binding Sites Open
A collection of 74 Enterobacteriaceae isolates found in Bo, Sierra Leone, were tested for quinolone antibiotic susceptibility and resistance mechanisms. The majority of isolates (62%) were resistant to quinolones, and 61% harbored chromoso…
View article: High prevalence of multidrug resistant Enterobacteriaceae isolated from outpatient urine samples but not the hospital environment in Bo, Sierra Leone
High prevalence of multidrug resistant Enterobacteriaceae isolated from outpatient urine samples but not the hospital environment in Bo, Sierra Leone Open