Chris Ware
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View article: Hydrometeorology and landscapes control sediment and dissolved organic carbon mobility across a diverse and changing glacier-sourced river basin
Hydrometeorology and landscapes control sediment and dissolved organic carbon mobility across a diverse and changing glacier-sourced river basin Open
Northern landscapes are enduring ongoing impacts of anthropogenic land use and climate change. Rivers are valuable indicators of this change reflected by the timing and amount of water and terrestrial material they mobilize. Assessing the …
View article: Hydrometeorology and landscapes control sediment and organic matter mobility across a diverse and changing glacier-sourced river basin
Hydrometeorology and landscapes control sediment and organic matter mobility across a diverse and changing glacier-sourced river basin Open
Northern landscapes are enduring ongoing impacts of anthropogenic land use and climate change. Rivers are valuable indicators of this change reflected by the timing and amount of water and terrestrial material they mobilize. Assessing the …
A habitat‐based approach to reporting the direct impacts of an organization on biodiversity Open
There is a rapidly growing need for efficient but rigorous methods for organizations to assess and disclose their biodiversity impacts. We devised a habitat‐based analytical approach for estimating the direct impacts of an organization on …
Farm revegetation has substantial potential to improve biodiversity outcomes Open
Agricultural expansion and intensification has caused habitat loss, contributing to the current biodiversity crisis. Reliable, efficient and consistent information at the farm-scale is critical to understand the magnitude of recent changes…
Accounting for Australia’s threatened species: Estimating historical and recent change in terrestrial habitat Open
Habitat retention and restoration are fundamental to minimising species extinctions. Mitigating impacts on threatened species habitat requires knowing where and how much habitat remains, the quality of the habitat, and how it is changing o…
Overcoming Key Challenges of Satellite-based Monitoring of Ecosystem Condition: A Continental-scale Example From Australia Open
Effective satellite-based monitoring of ecosystem integrity or condition needs to address four key challenges: (a) context dependency; (b) alternative ecological states; (c) short-term temporal ecosystem dynamics; and (d) scarcity of refer…
Ecosystem extent is a necessary but not sufficient indicator of the state of global forest biodiversity Open
The Kunming‐Montreal Global Biodiversity Framework lays out an ambitious set of goals and targets aimed at halting and reversing biodiversity loss. The extent of natural ecosystems has been selected as one of a small set of headline indica…
Spatial variation in avian bill size is associated with temperature extremes in a major radiation of Australian passerines Open
Morphology is integral to body temperature regulation. Recent advances in understanding of thermal physiology suggest a role of the avian bill in thermoregulation. To explore the adaptive significance of bill size for thermoregulation we c…
The value of targeted biological surveys: An assessment of Australia's Bush Blitz programme Open
Aim Biodiversity assessment and decisions rely on knowledge of the spatial distribution of species, yet most global biodiversity is inadequately represented by occurrence records. Efforts to improve our knowledge of biodiversity distributi…
Reporting the biodiversity impacts of greenhouse gas emissions Open
There are increasing demands for organisations and governments to report their biodiversity impacts, yet there are limited methods to account for the consequences of emitting greenhouse gases on global biodiversity. We use published eviden…
Supplementary Table S10 from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
Human breast tumor GE Notch Pathway.
Supplementary Table S9 from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
human Breast tumor Notch gene coverage annotations.
Supplementary Table S10 from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
Human breast tumor GE Notch Pathway.
Supplementary Methods from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
File includes genomic analysis, cell cycle and cell proliferation analysis.
Supplementary Methods from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
File includes genomic analysis, cell cycle and cell proliferation analysis.
Supplementary Tables S1 - S8 from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
Table S1: Analysis of Notch gene rearrangements in triple negative breast cancer subtypes. Table S2: Genes whose expression correlates with Notch gene-rearrangement status in cancer cell lines. Table S3: Genes whose expression correlates w…
Data from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
Next-generation sequencing was used to identify Notch mutations in a large collection of diverse solid tumors. NOTCH1 and NOTCH2 rearrangements leading to constitutive receptor activation were confined to triple-negative breast cancers (TN…
Supplementary Figures S1 - S7 from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
S1: NOTCH gene rearrangement in breast cancer cell lines and human breast tumors. S2: NOTCH gene rearrangement and sensitivity to MRK-003. S3: HES4 expression is associated with NOTCH gene-rearrangement or activating mutation in NOTCH. S4:…
Supplementary Figures S1 - S7 from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
S1: NOTCH gene rearrangement in breast cancer cell lines and human breast tumors. S2: NOTCH gene rearrangement and sensitivity to MRK-003. S3: HES4 expression is associated with NOTCH gene-rearrangement or activating mutation in NOTCH. S4:…
Data from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
Next-generation sequencing was used to identify Notch mutations in a large collection of diverse solid tumors. NOTCH1 and NOTCH2 rearrangements leading to constitutive receptor activation were confined to triple-negative breast cancers (TN…
Supplementary Tables S1 - S8 from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
Table S1: Analysis of Notch gene rearrangements in triple negative breast cancer subtypes. Table S2: Genes whose expression correlates with Notch gene-rearrangement status in cancer cell lines. Table S3: Genes whose expression correlates w…
Supplementary Table S9 from Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Open
human Breast tumor Notch gene coverage annotations.
View article: Supplementary Figure 1, Table 1 from <i>De novo</i> Discovery of a γ-Secretase Inhibitor Response Signature Using a Novel <i>In vivo</i> Breast Tumor Model
Supplementary Figure 1, Table 1 from <i>De novo</i> Discovery of a γ-Secretase Inhibitor Response Signature Using a Novel <i>In vivo</i> Breast Tumor Model Open
Supplementary Figure 1, Table 1 from De novo Discovery of a γ-Secretase Inhibitor Response Signature Using a Novel In vivo Breast Tumor Model
Data from Inhibition of Tumor Growth Progression by Antiandrogens and mTOR Inhibitor in a <i>Pten</i>-Deficient Mouse Model of Prostate Cancer Open
Androgen receptors have been shown to play a critical role in prostate cancer. We used ultrasound imaging techniques to track tumor response to antiandrogen and rapamycin treatment in a prostate-specific Pten-deleted mouse model of cancer.…
View article: Supplementary Figure 1, Table 1 from <i>De novo</i> Discovery of a γ-Secretase Inhibitor Response Signature Using a Novel <i>In vivo</i> Breast Tumor Model
Supplementary Figure 1, Table 1 from <i>De novo</i> Discovery of a γ-Secretase Inhibitor Response Signature Using a Novel <i>In vivo</i> Breast Tumor Model Open
Supplementary Figure 1, Table 1 from De novo Discovery of a γ-Secretase Inhibitor Response Signature Using a Novel In vivo Breast Tumor Model