Christian Botz-Zapp
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View article: Navigating Psychiatric Concerns in a Veteran Reporting Gulf War Illness: A Case Report
Navigating Psychiatric Concerns in a Veteran Reporting Gulf War Illness: A Case Report Open
Gulf War illness (GWI) is a chronic condition affecting nearly a third of Gulf War veterans and is characterized by persistent symptoms across a number of physical and neuropsychiatric domains. This case study examined a 52-year-old vetera…
View article: Differentiating neural sensitivity and bias during face-emotion processing in youth: a computational approach
Differentiating neural sensitivity and bias during face-emotion processing in youth: a computational approach Open
The ability to interpret face-emotion displays is critical for the development of adaptive social interactions. Using a novel variant of a computational model and fMRI data, we examined behavioral and neural associations between two metric…
View article: Persistent Frustration-Induced Reconfigurations of Brain Networks Predict Individual Differences in Irritability
Persistent Frustration-Induced Reconfigurations of Brain Networks Predict Individual Differences in Irritability Open
These pilot results suggest the importance of the postfrustration recovery period in the pathophysiology of irritability. Eglob in 3 specific posttask modules, involved in emotion processing, reward processing, or motor function…
View article: Effects of the selective dopamine D3 receptor antagonist PG01037 on morphine-induced hyperactivity and antinociception in mice
Effects of the selective dopamine D3 receptor antagonist PG01037 on morphine-induced hyperactivity and antinociception in mice Open
View article: A Randomized Controlled Trial of Computerized Interpretation Bias Training for Disruptive Mood Dysregulation Disorder: A Fast-Fail Study
A Randomized Controlled Trial of Computerized Interpretation Bias Training for Disruptive Mood Dysregulation Disorder: A Fast-Fail Study Open
View article: Rationale and validation of a novel mobile application probing motor inhibition: Proof of concept of CALM-IT
Rationale and validation of a novel mobile application probing motor inhibition: Proof of concept of CALM-IT Open
Identification of behavioral mechanisms underlying psychopathology is essential for the development of novel targeted therapeutics. However, this work relies on rigorous, time-intensive, clinic-based laboratory research, making it difficul…
View article: Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease
Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease Open
View article: Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer’s disease
Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer’s disease Open
See Grinberg and Heinsen (doi:10.1093/brain/awx261) for a scientific commentary on this article. Clinical evidence suggests that aberrant tau accumulation in the locus coeruleus and noradrenergic dysfunction may be a critical early step in…