Explanipedia

Horizon-scale variability of from 2017--2021 EHT observations Open

Kazunori Akiyama, Ezequiel Albentosa-Ruíz, A. Alberdi, Walter Alef, Juan Carlos Algaba , et al. · 2025

We report three epochs of polarized images of at 230,GHz using data from the Event Horizon Telescope (EHT) taken in 2017, 2018, and 2021. The baseline coverage of the 2021 observations is significantly improved through the addition of two …

Origin of the ring ellipticity in the black hole images of M87<sup>*</sup> Open

Rohan Dahale, Ilje Cho, Kotaro Moriyama, K. Wiik, Paul Tiede , et al. · 2025

We investigate the origin of the elliptical ring structure observed in the images of the supermassive black hole M87 * , aiming to disentangle contributions from gravitational, astrophysical, and imaging effects. Leveraging the enhanced ca…

First polarization study of the M87 jet and active galactic nuclei at submillimeter wavelengths with ALMA Open

C. Goddi, Douglas Ferreira Carlos, G. Crew, Lynn D. Matthews, Hugo Messias , et al. · 2025

Aims. We investigated the polarization and Faraday properties of Messier 87 (M87) and seven other radio-loud active galactic nuclei (AGNs) at λ 0.87 mm (345 GHz) using the Atacama Large Millimeter/submillimeter Array (ALMA). Our goal was t…

Characterising epi-perineurial barrier function by microscale techniques including a miniaturised Ussing chamber Open

Susanne M. Krug, I M Lee, Lukas Knobe, Beate Hartmannsberger, Mena Atalla , et al. · 2025

Barriers of peripheral nerves, like the sciatic nerve, are complex structures, consisting of the inner endoneurial capillary barriers and the outer epi‑ and perineurial layers. The latter two, collectively also known as epi‑perineurium (EP…

Effect of claudin-1 or -3 expression on cation and water channel properties of claudin-2 Open

Fabián Martínez-Perafán, Anja Fromm, Rozemarijn E. van der Veen, Ayk Waldow, Martin Lehmann , et al. · 2025

Claudin-2 (Cldn2) is a typical tight junction protein of leaky epithelia that forms paracellular channels for small cations and water. Claudin-3 (Cldn3) and claudin-1 (Cldn1) are barrier formers and may interact with Cldn2. We aimed to inv…

Special Issue “The Tight Junction and Its Proteins: From Structure to Pathologies” Open

Susanne M. Krug, Michael Fromm · 2024

Most tight junction (TJ) proteins build epithelial and endothelial barriers [...]

The impact of resistivity on the variability of black hole accretion flows Open

Antonios Nathanail, Yosuke Mizuno, Ioannis Contopoulos, Michael Fromm, Alejandro Cruz-Osorio , et al. · 2024

Context. The accretion of magnetized plasma onto black holes is a complex and dynamic process in which the magnetic field plays a crucial role. The amount of magnetic flux that is accumulated near the event horizon significantly impacts th…

Maissen, Thomas/May, Niels F./Kiesow, Rainer Maria (Hrsg.): Souveränität im Wandel. Frankreich und Deutschland. 14.–21. Jahrhundert, 518 S., Wallstein, Göttingen 2023. Open

Michael Fromm · 2024

A short guide to the tight junction Open

Sandra Citi, Michael Fromm, Mikio Furuse, Lorenza González‐Mariscal, Asma Nusrat , et al. · 2024

Tight junctions (TJs) are specialized regions of contact between cells of epithelial and endothelial tissues that form selective semipermeable paracellular barriers that establish and maintain body compartments with different fluid composi…

Expression and Localization Profiles of Tight Junction Proteins in Immune Cells Depend on Their Activation Status Open

Lena Voges, Franziska Weiß, Ana-Teresa Branco, Michael Fromm, Susanne M. Krug · 2024

The ability of the immune system to combat pathogens relies on processes like antigen sampling by dendritic cells and macrophages migrating through endo- and epithelia or penetrating them with their dendrites. In addition, other immune cel…

Comment on egusphere-2023-273 Open

Michael Fromm · 2023

Abstract. In the end of December 2019 and beginning of 2020, massive firestorms in Australia formed pyrocumulonimbus clouds (PyroCb) that acted like enormous smokestacks, pumping smoke to the upper troposphere and stratosp…

Cross-Domain Argument Quality Estimation Open

Michael Fromm, Max Berrendorf, Evgeniy Faerman, Thomas Seidl · 2023

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Clinical Significance of Claudin Expression in Oral Squamous Cell Carcinoma Open

Tatjana Zejc, Jörg Piontek, Jörg‐Dieter Schulzke, Michael Fromm, Jürgen Ervens , et al. · 2022

A change in claudin expression has been demonstrated in various tumors. The present study specifically compares claudin expression in oral squamous cell carcinoma (OSCC) with healthy oral epithelium from the same individual and analyzes th…

Obituary Prof. Dr. med. Johann Rastetter (28th of March 1928–23rd of June 2022)—a leading German hematologist Open

Wolfgang E. Berdel, Hermann Dietzfelbinger, Bertold Emmerich, Michael Fromm, Michael Hallek , et al. · 2022

Comment on acp-2022-253 Open

Michael Fromm · 2022

Abstract. We estimated geometric plume heights for the daytime eruptions of La Soufrière in April 2021 using visible red band geostationary side views and geostationary–polar orbiter stereo views. Most of the plumes either…

Comment on acp-2022-343 Open

Michael Fromm · 2022

Abstract. Wildfire smoke is known as a highly absorptive aerosol type in the shortwave wavelength range. The absorption of sunlight by optically thick smoke layers results in heating of the ambient air. This heating is tra…

Tight junction channels claudin‐10b and claudin‐15: Functional mapping of pore‐lining residues Open

Caroline Hempel, Rita Rosenthal, Anja Fromm, Susanne M. Krug, Michael Fromm , et al. · 2022

Although functional and structural models for paracellular channels formed by claudins have been reported, mechanisms regulating charge and size selectivity of these channels are unknown in detail. Here, claudin‐15 and claudin‐10b cation c…

Towards a Holistic View on Argument Quality Prediction Open

Michael Fromm, Max Berrendorf, Johanna Reiml, Isabelle Mayerhofer, S Bhargava , et al. · 2022

Argumentation is one of society's foundational pillars, and, sparked by advances in NLP and the vast availability of text data, automated mining of arguments receives increasing attention. A decisive property of arguments is their strength…

MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier Open

Franziska Weiß, Carolina Czichos, Lukas Knobe, Lena Voges, Christian Bojarski , et al. · 2022

In inflammatory bowel disease (IBD), the impaired intestinal barrier is mainly characterized by changes in tight junction protein expression. The functional role of the tight junction-associated MARVEL protein MARVELD3 (MD3) in IBD is yet …

Comment on amt-2021-333 Open

Michael Fromm · 2021

Abstract. We developed a technique to classify the composition of enhanced aerosol layers as either smoke or sulfuric acid aerosol using extinction spectra from the Stratospheric Aerosol and Gas Experiment III instrument a…

Measurement of tear resistance after manual capsulorhexis and femtosecond laser–assisted capsulotomy of crystalline lenses Open

Mandy Patzlaff-Günther, Michael Fromm, Thomas Kern, Martin Bartram, Anna Schwäblein , et al. · 2021

β-Catenin is Independently Associated With Outcome in Pancreatic Cancer: An Analysis of NRG Oncology/RTOG 9704 Open

Edgar Ben‐Josef, Kathryn Winter, Terence M. Williams, William F. Regine, Cynthia Timmers , et al. · 2021

High SMAD4 Expression is Associated With Better Clinical Outcomes in Patients With Resectable Pancreatic Cancer: An Analysis of NRG Oncology/RTOG 9704 Open

Terence M. Williams, Jennifer Moughan, Edgar Ben‐Josef, William F. Regine, Cynthia Timmers , et al. · 2021

Angulin-1 (LSR) Affects Paracellular Water Transport, However Only in Tight Epithelial Cells Open

Carlos Ayala‐Torres, Susanne M. Krug, Rita Rosenthal, Michael Fromm · 2021

Water transport in epithelia occurs transcellularly (aquaporins) and paracellularly (claudin-2, claudin-15). Recently, we showed that downregulated tricellulin, a protein of the tricellular tight junction (tTJ, the site where three epithel…

Correction to ‘Expression of mRNA electroporated into plant and animal cells’ Open

Judy Callis, Michael Fromm, Virginia Walbot · 2021

Expression of tricellular tight junction proteins and the paracellular macromolecule barrier are recovered in remission of ulcerative colitis Open

Jiachen Hu, Franziska Weiß, Christian Bojarski, Federica Branchi, Jörg‐Dieter Schulzke , et al. · 2021

The Tight Junction and Its Proteins Open

Michael Fromm, Susanne M. Krug · 2020

For a long time, the tight junction (TJ) was known to form and regulate the paracellular barrier between epithelia and endothelial cell sheets. Starting shortly after the discovery of the proteins forming the TJ—mainly the two families of …

MSH1-induced heritable enhanced growth vigor through grafting is associated with the RdDM pathway in plants Open

Hardik Kundariya, Xiaodong Yang, Kyla J. Morton, Robersy Sánchez, Michael J. Axtell , et al. · 2020

Leptin Downregulates Angulin-1 in Active Crohn’s Disease via STAT3 Open

Jiachen Hu, Christian Bojarski, Federica Branchi, Michael Fromm, Susanne M. Krug · 2020

Crohn’s disease (CD) has an altered intestinal barrier function, yet the underlying mechanisms remain to be disclosed. The tricellular tight junction protein tricellulin is involved in the maintenance of the paracellular macromolecule barr…

Special Issue on “The Tight Junction and Its Proteins: More than Just a Barrier” Open

Susanne M. Krug, Michael Fromm · 2020

For a long time, the tight junction (TJ) was known to form and regulate the paracellular barrier between epithelia and endothelial cell sheets. Starting shortly after the discovery of the proteins forming the TJ—mainly, the two families of…

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