Christian P. Pfeffer
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Enabling the detection of UV signal in multimodal nonlinear microscopy with catalogue lens components Open
Summary Using an optical system made from fused silica catalogue optical components, third‐order nonlinear microscopy has been enabled on conventional Ti:sapphire laser‐based multiphoton microscopy setups. The optical system is designed us…
Aortic valve replacement surgery reveals previously undiagnosed alkaptonuric ochronosis Open
alkaptonuric ochronosis Christian Pfeffer*, Erik Bagaev, Karl Sotlar and Christian Hagl a Herzchirurgische Klinik und Poliklinik der Ludwig-Maximilians-Universitat Munchen, Munich, Germany b Pathologisches Institut der Ludwig-Maximilians-U…
Imaging the noncentrosymmetric structural organization of tendon with Interferometric Second Harmonic Generation microscopy Open
We report the imaging of tendon with Interferometric Second Harmonic Generation microscopy. We observe that the noncentrosymmetric structural organization can be maintained along the fibrillar axis over more than 150 μm, while in the trans…
Imaging the noncentrosymmetric structural organisation of tissue with Interferometric Second Harmonic Generation microscopy Open
We report the imaging of tendon, a connective tissue rich in collagen type I proteins, with Interferometric Second Harmonic Generation (I-SHG) microscopy. We observed that the noncentrosymmetric structural organization can be maintained al…
Imaging the noncentrosymmetric structural organisation of tissue with\n Interferometric Second Harmonic Generation microscopy Open
We report the imaging of tendon, a connective tissue rich in collagen type I\nproteins, with Interferometric Second Harmonic Generation (I-SHG) microscopy.\nWe observed that the noncentrosymmetric structural organization can be\nmaintained…
Imaging skeletal muscle using second harmonic generation and coherent anti-Stokes Raman scattering microscopy Open
We describe experimental results on label free imaging of striated skeletal muscle using second harmonic generation (SHG) and coherent anti-Stokes Raman scattering (CARS) microscopy. The complementarity of the SHG and CARS data makes it po…
Second harmonic generation imaging of fascia within thick tissue block Open
Comparing the SHG image formation for thin sections of tail tendon fascia and skeletal muscle fascia, we demonstrate that the forward (F) and backward (B) SHG images are vastly different. In addition, despite the different arrangement of t…
Processing, localization, and requirement of human separase for normal anaphase progression Open
In all eukaryotes, anaphase is triggered by the activation of a protease called separase. Once activated, separase cleaves a subunit of cohesin, a complex that links replicated chromatids before anaphase. Separase and cohesin are conserved…