Christian Rassi
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View article: Global medium-term research priority setting for seasonal malaria chemoprevention: results from an eDelphi study
Global medium-term research priority setting for seasonal malaria chemoprevention: results from an eDelphi study Open
Introduction Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SPAQ) has been delivered in sub-Saharan Africa since 2014, reaching over 40 million children in 2022. New questions are emerging related to…
View article: Pharmacometric evaluation of amodiaquine-sulfadoxine-pyrimethamine and dihydroartemisinin-piperaquine seasonal malaria chemoprevention in northern Uganda
Pharmacometric evaluation of amodiaquine-sulfadoxine-pyrimethamine and dihydroartemisinin-piperaquine seasonal malaria chemoprevention in northern Uganda Open
Background Seasonal malaria chemoprevention (SMC) using monthly amodiaquine-sulfadoxine-pyrimethamine (SPAQ) is being deployed East Africa, where antimalarial drug resistance levels are high. Dihydroartemisinin-piperaquine (DP) is a potent…
View article: Seasonal malaria chemoprevention in northern Mozambique: a cost-effectiveness analysis
Seasonal malaria chemoprevention in northern Mozambique: a cost-effectiveness analysis Open
View article: Impact of seasonal malaria chemoprevention: a plausibility evaluation of routine data from health facilities in three implementing states in Nigeria
Impact of seasonal malaria chemoprevention: a plausibility evaluation of routine data from health facilities in three implementing states in Nigeria Open
Background Seasonal malaria chemoprevention (SMC) has been recommended by the World Health Organization since 2012 for children aged 3–59 months in areas where malaria transmission is highly seasonal. By 2024, SMC had been successfully imp…
View article: Phase one of a hybrid effectiveness-implementation study to assess the feasibility, acceptability and effectiveness of implementing seasonal malaria chemoprevention in Nampula Province, Mozambique
Phase one of a hybrid effectiveness-implementation study to assess the feasibility, acceptability and effectiveness of implementing seasonal malaria chemoprevention in Nampula Province, Mozambique Open
Background Seasonal malaria chemoprevention (SMC) is a highly effective intervention for malaria prevention in high burden areas with seasonal transmission, historically implemented in the Sahel. Mozambique contributes to 4% of global mala…
View article: Digital Transformation of Campaign Delivery: Cost and Efficiency Insights from Mozambique’s Seasonal Malaria Chemoprevention Programme
Digital Transformation of Campaign Delivery: Cost and Efficiency Insights from Mozambique’s Seasonal Malaria Chemoprevention Programme Open
View article: Adaptation of lot quality assurance sampling to monitor seasonal malaria chemoprevention delivery performance
Adaptation of lot quality assurance sampling to monitor seasonal malaria chemoprevention delivery performance Open
Malaria Consortium supports delivery of seasonal malaria chemoprevention (SMC) to children ages 3–59 months using sulfadoxine–pyrimethamine plus amodiaquine. Lot quality assurance sampling (LQAS) was adapted as a cost-efficient method for …
View article: Barriers to the quality delivery of seasonal malaria chemoprevention in Chad and Burkina Faso: a qualitative exploration of caregivers and community distributors’ perspectives
Barriers to the quality delivery of seasonal malaria chemoprevention in Chad and Burkina Faso: a qualitative exploration of caregivers and community distributors’ perspectives Open
View article: Correction: Receipt of seasonal malaria chemoprevention by age-ineligible children and associated factors in nine implementation states in Nigeria
Correction: Receipt of seasonal malaria chemoprevention by age-ineligible children and associated factors in nine implementation states in Nigeria Open
View article: Receipt of seasonal malaria chemoprevention by age-ineligible children and associated factors in nine implementation states in Nigeria
Receipt of seasonal malaria chemoprevention by age-ineligible children and associated factors in nine implementation states in Nigeria Open
View article: From efficacy to effectiveness: a comprehensive framework for monitoring, evaluating and optimizing seasonal malaria chemoprevention programmes
From efficacy to effectiveness: a comprehensive framework for monitoring, evaluating and optimizing seasonal malaria chemoprevention programmes Open
View article: A quasi-experimental study to estimate effectiveness of seasonal malaria chemoprevention in Aweil South County in Northern Bahr El Ghazal, South Sudan
A quasi-experimental study to estimate effectiveness of seasonal malaria chemoprevention in Aweil South County in Northern Bahr El Ghazal, South Sudan Open
Background Seasonal malaria chemoprevention (SMC) is an effective intervention to prevent malaria in children in locations where the burden of malaria is high and transmission is seasonal. There is growing evidence suggesting that SMC with…
View article: Results from phase one of a hybrid effectiveness-implementation study to assess the feasibility, acceptability and effectiveness of implementing seasonal malaria chemoprevention in Nampula province, Mozambique
Results from phase one of a hybrid effectiveness-implementation study to assess the feasibility, acceptability and effectiveness of implementing seasonal malaria chemoprevention in Nampula province, Mozambique Open
Introduction Seasonal malaria chemoprevention (SMC) is a highly effective intervention for malaria prevention in high burden areas with seasonal transmission, historically implemented in the Sahel. Mozambique contributes to 4% of global ma…
View article: Urban–rural differences in seasonal malaria chemoprevention coverage and characteristics of target populations in nine states of Nigeria: a comparative cross-sectional study
Urban–rural differences in seasonal malaria chemoprevention coverage and characteristics of target populations in nine states of Nigeria: a comparative cross-sectional study Open
Background Differences between urban and rural contexts in terms of sociodemographic characteristics, geographical features and risk perceptions may lead to disparities in coverage and related outcomes of community-based preventive interve…
View article: A Cluster Randomised Controlled Trial to Evaluate the Effectiveness of Sulfadoxine-Pyrimethamine Plus Amodiaquine and Dihydroartemisinin-Piperaquine for Seasonal Malaria Chemoprevention in Uganda
A Cluster Randomised Controlled Trial to Evaluate the Effectiveness of Sulfadoxine-Pyrimethamine Plus Amodiaquine and Dihydroartemisinin-Piperaquine for Seasonal Malaria Chemoprevention in Uganda Open
View article: A hybrid effectiveness-implementation study protocol to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda
A hybrid effectiveness-implementation study protocol to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda Open
Background The World Health Organization (WHO) recommends seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SPAQ) for children aged 3 to 59 months, living in areas where malaria transmission is highly s…
View article: From Efficacy to Effectiveness: a Comprehensive Framework for Monitoring, Evaluating and Optimising Seasonal Malaria Chemoprevention Programmes
From Efficacy to Effectiveness: a Comprehensive Framework for Monitoring, Evaluating and Optimising Seasonal Malaria Chemoprevention Programmes Open
Background Seasonal Malaria Chemoprevention (SMC) is a highly effective intervention for preventing malaria, particularly in areas with highly seasonal transmission. Monitoring and evaluating (M&E) SMC programmes are complex due to the sca…
View article: Rapid assessments for the deployment of seasonal malaria chemoprevention in new geographies of east and southern Africa: protocol for a hybrid type II implementation study. (Preprint)
Rapid assessments for the deployment of seasonal malaria chemoprevention in new geographies of east and southern Africa: protocol for a hybrid type II implementation study. (Preprint) Open
BACKGROUND Seasonal malaria chemoprevention (SMC) is a highly effective community-based intervention to prevent malaria infections caused by Plasmodium falciparum in areas where the burden of malaria is high and malaria transmission is se…
View article: Rapid assessments for the deployment of seasonal malaria chemoprevention in new geographies of east and southern Africa: protocol for a hybrid type II implementation study. (Preprint)
Rapid assessments for the deployment of seasonal malaria chemoprevention in new geographies of east and southern Africa: protocol for a hybrid type II implementation study. (Preprint) Open
View article: Receipt of seasonal malaria chemoprevention by age-ineligible children and associated factors in nine implementation states in Nigeria
Receipt of seasonal malaria chemoprevention by age-ineligible children and associated factors in nine implementation states in Nigeria Open
Background: As part of implementation quality standards, community distributors are expected to ensure that only age-eligible children (aged 3 – 59 months) receive seasonal malaria chemoprevention (SMC) medicines during monthly campaigns. …
View article: A quasi-experimental study to estimate effectiveness of Seasonal Malaria Chemoprevention in Aweil South County in Northern Bahr El Ghazal, South Sudan.
A quasi-experimental study to estimate effectiveness of Seasonal Malaria Chemoprevention in Aweil South County in Northern Bahr El Ghazal, South Sudan. Open
Background Seasonal malaria chemoprevention (SMC) is an effective intervention to prevent malaria in children in locations where the burden of malaria is high and transmission is seasonal. There is growing evidence suggesting that SMC with…
View article: Predictors of caregiver adherence to administration of amodiaquine during delivery of seasonal malaria chemoprevention in Nigeria, Burkina Faso, Chad, and Togo
Predictors of caregiver adherence to administration of amodiaquine during delivery of seasonal malaria chemoprevention in Nigeria, Burkina Faso, Chad, and Togo Open
Background Malaria is the leading cause of morbidity and mortality among infants and children under-five in sub-Saharan Africa. In the Sahel, seasonal malaria chemoprevention (SMC) is delivered door-to-door in monthly cycles. In each cycle…
View article: A non-randomized controlled trial to assess the protective effect of SMC in the context of high parasite resistance in Uganda
A non-randomized controlled trial to assess the protective effect of SMC in the context of high parasite resistance in Uganda Open
Background Until recently, due to widespread prevalence of molecular markers associated with sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) resistance in east and southern Africa, seasonal malaria chemoprevention (SMC) has not been us…
View article: A hybrid effectiveness-implementation study protocol to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda
A hybrid effectiveness-implementation study protocol to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda Open
Background: The World Health Organization (WHO) recommends seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine for children aged 3 to 59 months, living in areas where malaria transmission is highly seasona…
View article: Potential Suitability of Sulfadoxine-Pyrimethamine Plus Amodiaquine for Seasonal Malaria Chemoprevention in Areas of High, Pre-Existing Drug Resistance
Potential Suitability of Sulfadoxine-Pyrimethamine Plus Amodiaquine for Seasonal Malaria Chemoprevention in Areas of High, Pre-Existing Drug Resistance Open
View article: A non-randomised controlled trial to assess the protective effect of SMC in the context of high parasite resistance in Uganda
A non-randomised controlled trial to assess the protective effect of SMC in the context of high parasite resistance in Uganda Open
Background : Until recently, due to widespread prevalence of molecular markers associated with sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) resistance in east and southern Africa, seasonal malaria chemoprevention (SMC) has not been …
View article: Feasibility, Acceptability, and Protective Efficacy of Seasonal Malaria Chemoprevention Implementation in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study
Feasibility, Acceptability, and Protective Efficacy of Seasonal Malaria Chemoprevention Implementation in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study Open
Background Seasonal malaria chemoprevention (SMC) is a highly effective community-based intervention to prevent malaria infections in areas where the malaria burden is high and transmission occurs mainly during the rainy season. In Africa,…
View article: Impact of seasonal malaria chemoprevention on prevalence of malaria infection in malaria indicator surveys in Burkina Faso and Nigeria
Impact of seasonal malaria chemoprevention on prevalence of malaria infection in malaria indicator surveys in Burkina Faso and Nigeria Open
Background In 2012, the WHO issued a policy recommendation for the use of seasonal malaria chemoprevention (SMC) to children 3–59 months in areas of highly seasonal malaria transmission. Clinical trials have found SMC to prevent around 75%…
View article: Extending seasonal malaria chemoprevention to five cycles: a pilot study of feasibility and acceptability in Mangodara district, Burkina Faso
Extending seasonal malaria chemoprevention to five cycles: a pilot study of feasibility and acceptability in Mangodara district, Burkina Faso Open
View article: A protocol for a hybrid effectiveness-implementation study to assess the feasibility, acceptability and protective efficacy of implementing seasonal malaria chemoprevention in Nampula province, Mozambique (Preprint)
A protocol for a hybrid effectiveness-implementation study to assess the feasibility, acceptability and protective efficacy of implementing seasonal malaria chemoprevention in Nampula province, Mozambique (Preprint) Open
BACKGROUND Seasonal malaria chemoprevention (SMC) is a highly effective community-based intervention to prevent malaria infections in areas where the malaria burden is high and transmission occurs mainly during the rainy season. In Africa…