Explanipedia

On the inverse association between the number of QTL and the trait-specific genomic relationship of a candidate to the training set. Open

Christian Stricker, Rohan L. Fernando, Albrecht E. Melchinger, Hans-Juergen Auinger, Chris-Carolin Schoen · 2024

Background Accuracy of genomic prediction depends on the heritability of the trait, the size of the training set, the relationship of the candidates to the training set, and the $$\text {Min}(N_{\text {QTL}},M_e)$$ , where $$N_…

Genomic prediction in hybrid breeding: I. Optimizing the training set design Open

Albrecht E. Melchinger, Rohan L. Fernando, Christian Stricker, Chris‐Carolin Schön, Hans-Jürgen Auinger · 2023

Key message Training sets produced by maximizing the number of parent lines, each involved in one cross, had the highest prediction accuracy for H0 hybrids, but lowest for H1 and H2 hybrids. Abstract Genomic prediction holds great promise …

Noradrenaline Increases mEPSC Frequency in Pyramidal Cells in Layer II of Rat Barrel Cortex via Calcium Release From Presynaptic Stores Open

Julian M. C. Choy, Fransiscus Adrian Agahari, Li Li, Christian Stricker · 2018

Somatosensory cortex is innervated by afferents originating from the locus coeruleus which typically release noradrenaline. We tested if activation of presynaptic α₁-adrenoceptors (AR) coupled to a G_q-mediated …

Diffusion of Ca2+ from Small Boutons en Passant into the Axon Shapes AP-Evoked Ca2+ Transients Open

Van Tran, Christian Stricker · 2018

Highly accurate sequence imputation enables precise QTL mapping in Brown Swiss cattle Open

Mirjam Frischknecht, Hubert Pausch, Beat Bapst, Heidi Signer‐Hasler, Christine Flury , et al. · 2017

Genome-wide association studies of fertility and calving traits in Brown Swiss cattle using imputed whole-genome sequences Open

Mirjam Frischknecht, Beat Bapst, Franz R. Seefried, Heidi Signer‐Hasler, Dorian J. Garrick , et al. · 2017

Short communication: Genomic prediction using imputed whole-genome sequence variants in Brown Swiss Cattle Open

Mirjam Frischknecht, Theodorus Meuwissen, Beat Bapst, Franz R. Seefried, Christine Flury , et al. · 2017

The accuracy of genomic prediction determines response to selection. It has been hypothesized that accuracy of genomic breeding values can be increased by a higher density of variants. We used imputed whole-genome sequence data and various…

Population structure and genomic inbreeding in nine Swiss dairy cattle populations Open

Heidi Signer‐Hasler, Alexander Burren, Markus Neuditschko, Mirjam Frischknecht, Dorian J. Garrick , et al. · 2017

Improving Focal Photostimulation of Cortical Neurons with Pre-derived Wavefront Correction Open

Julian M. C. Choy, Sharmila S. Sané, Woei Ming Lee, Christian Stricker, Hans‐A. Bachor , et al. · 2017

Recent progress in neuroscience to image and investigate brain function has been made possible by impressive developments in optogenetic and opto-molecular tools. Such research requires advances in optical techniques for the delivery of li…

Additional file 1: Table S1. of Highly accurate sequence imputation enables precise QTL mapping in Brown Swiss cattle Open

Mirjam Frischknecht, Hubert Pausch, Beat Bapst, Heidi Signer‐Hasler, Christine Flury , et al. · 2017

Breed codes and number of individuals per breed within the fifth run of the 1000 Bull Genomes Project. Table S2. Average number of SNPs per minor allele frequency class in S5, S6 and S7. Table S3. Imputation accuracy per breed in S1. Table…

MOESM15 of Population structure and genomic inbreeding in nine Swiss dairy cattle populations Open

Heidi Signer‐Hasler, Alexander Burren, Markus Neuditschko, Mirjam Frischknecht, Dorian J. Garrick , et al. · 2017

Additional file 15: Table S7. Genomic coordinates (chromosome and startâ and endâ position) of all significant windows, the population for which d i was calculated, and genes within this region.

Additional file 6: Table S2. of Genome-wide association studies of fertility and calving traits in Brown Swiss cattle using imputed whole-genome sequences Open

Mirjam Frischknecht, Beat Bapst, Franz R. Seefried, Heidi Signer‐Hasler, Dorian J. Garrick , et al. · 2017

Minor allele frequency per breed among sequenced individuals for ASCC2 and GAS2L1. (XLSX 44Â kb)

Additional file 5: Table S1. of Genome-wide association studies of fertility and calving traits in Brown Swiss cattle using imputed whole-genome sequences Open

Mirjam Frischknecht, Beat Bapst, Franz R. Seefried, Heidi Signer‐Hasler, Dorian J. Garrick , et al. · 2017

GWAS results per trait. SNPs with p-values

Targeted pruning of a neuron’s dendritic tree via femtosecond laser dendrotomy Open

Mary Ann Go, Julian M. C. Choy, Alexandru S. Colibaba, Stephen Redman, Hans‐A. Bachor , et al. · 2016

Neurons are classified according to action potential firing in response to current injection. While such firing patterns are shaped by the composition and distribution of ion channels, modelling studies suggest that the geometry of dendrit…

Genome-wide association study in Brown Swiss for udder traits based on sequence data Open

Mirjam Frischknecht, Christine Flury, Beat Bapst, Franz R. Seefried, Heidi Signer‐Hasler , et al. · 2016

Identification of QTL, especially of causative variants within QTL is still challenging. Higher SNP densities aid the identification and fine-mapping of QTL. Based on imputed sequence data we performed GWAS for udder traits in Brown Swiss …

Genomic prediction using haplotypes in Brown Swiss Open

Mirjam Frischknecht, Franz R. Seefried, Beat Bapst, Christine Flury, Heidi Signer‐Hasler , et al. · 2016

In order to improve accuracy of genomic selection different approaches have been suggested. One possibility is to use haplotypes instead of SNPs. It is thought that by the usage of haplotypes the number of effects to estimate should be dec…

Identifying signature Zernike modes for efficient light delivery through brain tissue Open

Sharmila S. Sané, Julian M. C. Choy, Woei Ming Lee, Christian Stricker, Hans‐A. Bachor , et al. · 2015

Recent progress in neuroscience to image and investigate brain function has been made possible by impressive developments in optogenetic and opto-molecular tools. Such research requires advances in optical techniques for the delivery of li…

Improved two-photon imaging of living neurons in brain tissue through temporal gating Open

Vini Gautam, J C Drury, Julian M. C. Choy, Christian Stricker, Hans‐A. Bachor , et al. · 2015

We optimize two-photon imaging of living neurons in brain tissue by temporally gating an incident laser to reduce the photon flux while optimizing the maximum fluorescence signal from the acquired images. Temporal gating produces a bunch o…

Christian Stricker YOU? Author Swipe