Christian Weimar
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View article: Joint effects of environmental and neighborhood socioeconomic factors on cognitive function in the Heinz Nixdorf Recall Study
Joint effects of environmental and neighborhood socioeconomic factors on cognitive function in the Heinz Nixdorf Recall Study Open
We identified associations between distinct combinations of intercorrelated air pollution, road traffic noise, and nSEP disadvantages with poorer cognitive function, using two different dimensionality reduction methods. Our findings highli…
View article: Sex‐ and age‐specific effect of known type 2 diabetes mellitus on incident mild cognitive impairment five years later: Results from the population‐based Heinz Nixdorf Recall study
Sex‐ and age‐specific effect of known type 2 diabetes mellitus on incident mild cognitive impairment five years later: Results from the population‐based Heinz Nixdorf Recall study Open
Introduction As studies on the association between type 2 diabetes mellitus (T2DM) and mild cognitive impairment (MCI), including amnestic (aMCI) and non‐amnestic (naMCI) subtypes, vary by sex and age, we investigated the sex‐ and age‐spec…
View article: Prior Anticoagulation and Risk of Hemorrhagic Transformation in Acute Stroke: A Post Hoc Analysis of the PRODAST Study
Prior Anticoagulation and Risk of Hemorrhagic Transformation in Acute Stroke: A Post Hoc Analysis of the PRODAST Study Open
Background Oral anticoagulation is highly effective in preventing ischemic events in patients with atrial fibrillation. Still, a considerable number of patients have an acute ischemic stroke or transient ischemic attack despite anticoagula…
View article: Joint Effects of Environmental and Socioeconomic Contextual Factors on Cognitive Function in the Heinz Nixdorf Recall Study
Joint Effects of Environmental and Socioeconomic Contextual Factors on Cognitive Function in the Heinz Nixdorf Recall Study Open
View article: Colchicine for secondary prevention of ischaemic stroke and atherosclerotic events: a meta-analysis of randomised trials
Colchicine for secondary prevention of ischaemic stroke and atherosclerotic events: a meta-analysis of randomised trials Open
There was no funding source for this study.
View article: New recommendations on cerebral venous and dural sinus thrombosis from the German consensus-based (S2k) guideline
New recommendations on cerebral venous and dural sinus thrombosis from the German consensus-based (S2k) guideline Open
Over the last years, new evidence has accumulated on multiple aspects of diagnosis and management of cerebral venous and dural sinus thrombosis (CVT) including identification of new risk factors, studies on interventional treatment as well…
View article: Efficacy and safety of oral factor Xa inhibitors versus vitamin-K antagonists in the early phase after acute ischemic stroke or TIA in the real-world setting: The PRODAST study
Efficacy and safety of oral factor Xa inhibitors versus vitamin-K antagonists in the early phase after acute ischemic stroke or TIA in the real-world setting: The PRODAST study Open
Introduction: Factor Xa (FXa) inhibitors are superior to vitamin K antagonists (VKAs) in terms of avoiding hemorrhagic complications. However, no robust data are available to date as to whether this also applies to the early phase after st…
View article: Tobacco use and risk of acute stroke in 32 countries in the INTERSTROKE study: a case–control study
Tobacco use and risk of acute stroke in 32 countries in the INTERSTROKE study: a case–control study Open
View article: Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury
Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury Open
View article: Association of white matter hyperintensity burden and cognitive performance in young‐aged, middle‐aged and old‐aged participants: Results of the population‐based 1000BRAINS study
Association of white matter hyperintensity burden and cognitive performance in young‐aged, middle‐aged and old‐aged participants: Results of the population‐based 1000BRAINS study Open
Background Some individuals seem less susceptible to the effect of high white matter hyperintensity (WMH) load on cognition reflecting differences in individual cognitive reserve (CR). Little is known about young‐ or middle‐aged participan…
View article: Guidelines for neuroprognostication in adults with traumatic spinal cord injury
Guidelines for neuroprognostication in adults with traumatic spinal cord injury Open
View article: Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage
Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage Open
View article: Calibrating machine learning approaches for probability estimation: A comprehensive comparison
Calibrating machine learning approaches for probability estimation: A comprehensive comparison Open
Statistical prediction models have gained popularity in applied research. One challenge is the transfer of the prediction model to a different population which may be structurally different from the model for which it has been developed. A…
View article: Underlying Causes of TIA and Minor Ischemic Stroke and Risk of Major Vascular Events
Underlying Causes of TIA and Minor Ischemic Stroke and Risk of Major Vascular Events Open
Importance The coexistence of underlying causes in patients with transient ischemic attack (TIA) or minor ischemic stroke as well as their associated 5-year risks are not well known. Objective To apply the ASCOD (atherosclerosis, small ves…
View article: Author Correction: Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome
Author Correction: Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome Open
View article: Outcome after intracranial hemorrhage under dabigatran and reversal with idarucizumab versus under vitamin-K-antagonists – the RIC-ICH study
Outcome after intracranial hemorrhage under dabigatran and reversal with idarucizumab versus under vitamin-K-antagonists – the RIC-ICH study Open
Background Intracranial hemorrhage (ICH) is a rare but serious side effect associated with the use of oral anticoagulants, such as dabigatran. The specific reversal agent for dabigatran, idarucizumab, is available for the management of ind…
View article: Early or late initiation of dabigatran versus vitamin-K-antagonists in acute ischemic stroke or TIA: The PRODAST study
Early or late initiation of dabigatran versus vitamin-K-antagonists in acute ischemic stroke or TIA: The PRODAST study Open
Background: The optimal timing of initiating or resuming anticoagulation after acute ischemic stroke (AIS) or transient ischemic attack (TIA) in patients with atrial fibrillation (AF) is debated. Dabigatran, a non-vitamin K oral anticoagul…
View article: Association of long-term air pollution and ambient noise with cognitive decline in the Heinz Nixdorf Recall study
Association of long-term air pollution and ambient noise with cognitive decline in the Heinz Nixdorf Recall study Open
Little is known about the impact of long-term ambient air pollution (AP) and noise exposure on change in cognitive function over years in the elderly. In this study, we wanted to examine the association between long-term exposure to AP and…
View article: Correction to: Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome
Correction to: Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome Open
View article: Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome
Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome Open
Background Guillain–Barré syndrome (GBS) often carries a favorable prognosis. Of adult patients with GBS, 10–30% require mechanical ventilation during the acute phase of the disease. After the acute phase, the focus shifts to restoration o…
View article: Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome
Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome Open
Background Guillain–Barré syndrome (GBS) often carries a favorable prognosis. Of adult patients with GBS, 10–30% require mechanical ventilation during the acute phase of the disease. After the acute phase, the focus shifts to restoration o…
View article: Guidelines for Neuroprognostication in Comatose Adult Survivors of Cardiac Arrest
Guidelines for Neuroprognostication in Comatose Adult Survivors of Cardiac Arrest Open
View article: Association of Long-Term Air Pollution and Ambient Noise with Cognitive Decline in the Heinz Nixdorf Recall Study
Association of Long-Term Air Pollution and Ambient Noise with Cognitive Decline in the Heinz Nixdorf Recall Study Open
View article: Stroke Outcome Related to Initial Volume Status and Diuretic Use
Stroke Outcome Related to Initial Volume Status and Diuretic Use Open
Background We hypothesized that stroke outcome is related to multiple baseline hydration‐related factors including volume contracted state (VCS) and diuretic use. Methods and Results We analyzed a prospective cohort of subjects with ischem…
View article: Fluctuation of depressive symptoms in cognitively unimpaired participants and the risk of mild cognitive impairment 5 years later: Results of the Heinz Nixdorf Recall study
Fluctuation of depressive symptoms in cognitively unimpaired participants and the risk of mild cognitive impairment 5 years later: Results of the Heinz Nixdorf Recall study Open
Background Depression might be an independent risk factor for cognitive decline, a prodromal dementia symptom or a reaction to cognitive/functional impairment. Objective To investigate the association between (1) depressive symptoms and (2…
View article: Five-Year Results of Coronary Artery Bypass Grafting With or Without Carotid Endarterectomy in Patients With Asymptomatic Carotid Artery Stenosis: CABACS RCT
Five-Year Results of Coronary Artery Bypass Grafting With or Without Carotid Endarterectomy in Patients With Asymptomatic Carotid Artery Stenosis: CABACS RCT Open
Background: In patients with coronary artery disease and concomitant asymptomatic severe carotid stenosis, combined simultaneous coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA) has been widely performed despite lack…
View article: Validity of the Early Functional Ability scale (EFA) among critically ill patients undergoing early neurological rehabilitation
Validity of the Early Functional Ability scale (EFA) among critically ill patients undergoing early neurological rehabilitation Open
Background A reliable assessment of the functional abilities of patients after severe brain damage is crucial for valid prognostication and treatment decisions, but most clinical scales are of limited use among this specific group of patie…
View article: Intraoperative Flow Measurement as a Quality Control during Carotid Endarterectomy in a Teaching Hospital Setting
Intraoperative Flow Measurement as a Quality Control during Carotid Endarterectomy in a Teaching Hospital Setting Open
Background: To evaluate the technical results of an arterial repair, a variety of intraoperative imaging and assessment techniques can be used during carotid endarterectomy (CEA). The aim of the study was to evaluate the usefulness of intr…
View article: Revacept, an Inhibitor of Platelet Adhesion in Symptomatic Carotid Stenosis: A Multicenter Randomized Phase II Trial
Revacept, an Inhibitor of Platelet Adhesion in Symptomatic Carotid Stenosis: A Multicenter Randomized Phase II Trial Open
Background: Patients with symptomatic internal carotid artery (ICA) stenosis are at high risk of recurrent ischemic stroke and require early interventional treatment and antiplatelet therapy. Increased bleeding rates might counterbalance t…
View article: Association of Lipids, Lipoproteins, and Apolipoproteins with Stroke Subtypes in an International Case Control Study (INTERSTROKE)
Association of Lipids, Lipoproteins, and Apolipoproteins with Stroke Subtypes in an International Case Control Study (INTERSTROKE) Open
Background and Purpose The association of dyslipidemia with stroke has been inconsistent, which may be due to differing associations within etiological stroke subtypes. We sought to determine the association of lipoproteins and apolipoprot…