Christian Zauner
YOU?
Author Swipe
View article: Bleeding complications in patients with out-of-hospital cardiac arrest treated with cangrelor and oral P2Y12 inhibitors
Bleeding complications in patients with out-of-hospital cardiac arrest treated with cangrelor and oral P2Y12 inhibitors Open
Aims Cangrelor is used to bridge the gap of insufficient platelet inhibition in patients with out-of-hospital cardiac arrest (OHCA) undergoing percutaneous coronary intervention (PCI). Methods and results In a retrospective chart review st…
View article: Acute liver failure in patients admitted to the intensive care unit—a Viennese retrospective single-center analysis
Acute liver failure in patients admitted to the intensive care unit—a Viennese retrospective single-center analysis Open
Summary Background Acute liver failure (ALF) is characterized by a rapid deterioration of liver function and a high mortality without transplantation depending on etiology and onset. Immediate transfer to a dedicated intensive care unit (I…
View article: Extracorporeal Cardiopulmonary Resuscitation: Outcomes Improve With Center Experience
Extracorporeal Cardiopulmonary Resuscitation: Outcomes Improve With Center Experience Open
After restructuring the Vienna eCPR program, we were able to improve survival rates with favorable neurologic outcomes after eCPR. This improvement was accompanied with increased case volumes, rates of witnessed arrest, bystander CPR, and …
View article: The Influence of Prone Positioning on Energy and Protein Delivery in COVID-19 Patients Requiring ECMO Support
The Influence of Prone Positioning on Energy and Protein Delivery in COVID-19 Patients Requiring ECMO Support Open
Background: Gastrointestinal dysfunction is a common complication of medical nutrition therapy in critically ill patients. Whether prone positioning leads to a deterioration in gastrointestinal function has not been fully clarified. Thus, …
View article: Use of the CytoSorb adsorber in patients with acute-on-chronic liver failure
Use of the CytoSorb adsorber in patients with acute-on-chronic liver failure Open
CytoSorb is a hemoadsorptive column used to remove high concentrations of proinflammatory cytokines in septic shock. Data on CytoSorb application in acute-on-chronic liver failure (ACLF) is lacking. This retrospective observational study a…
View article: Hypophosphatemia after Start of Medical Nutrition Therapy Indicates Early Refeeding Syndrome and Increased Electrolyte Requirements in Critically Ill Patients but Has No Impact on Short-Term Survival
Hypophosphatemia after Start of Medical Nutrition Therapy Indicates Early Refeeding Syndrome and Increased Electrolyte Requirements in Critically Ill Patients but Has No Impact on Short-Term Survival Open
Refeeding syndrome (RFS) is a potentially life-threatening complication in malnourished (critically ill) patients. The presence of various accepted RFS definitions and the inclusion of heterogeneous patient populations in the literature ha…
View article: Characteristics and outcome of critically ill patients with systemic rheumatic diseases referred to the intensive care unit
Characteristics and outcome of critically ill patients with systemic rheumatic diseases referred to the intensive care unit Open
Objectives Patients with systemic rheumatic diseases (SRDs) are at risk of admission to the intensive care unit (ICU). Data concerning these critically ill patients are limited to few retrospective studies. Methods This is a single-centre …
View article: Sustained Treatment Response after Intravenous Cyclophosphamide in a Patient with Therapy-Resistant COVID-19 Acute Respiratory Distress Syndrome: A Case Report
Sustained Treatment Response after Intravenous Cyclophosphamide in a Patient with Therapy-Resistant COVID-19 Acute Respiratory Distress Syndrome: A Case Report Open
Treatment of acute respiratory distress syndrome (ARDS) represents a severe complication of coronavirus disease 2019 (COVID-19) infection and is often challenging in intensive care treatment. Potential positive effects of intravenous cyclo…
View article: Inadequate Energy Delivery Is Frequent among COVID-19 Patients Requiring ECMO Support and Associated with Increased ICU Mortality
Inadequate Energy Delivery Is Frequent among COVID-19 Patients Requiring ECMO Support and Associated with Increased ICU Mortality Open
Background: Patients receiving extracorporeal membrane oxygenation (ECMO) support are at high risk for malnutrition. There are currently no general nutrition guidelines for coronavirus disease 2019 (COVID-19) patients during ECMO therapy. …
View article: Disturbances in sodium and chloride homeostasis predict outcome in stable and critically ill patients with cirrhosis
Disturbances in sodium and chloride homeostasis predict outcome in stable and critically ill patients with cirrhosis Open
Summary Background Hyponatremia has prognostic implications in patients with cirrhosis, and thus, has been incorporated in the 2016 MELD‐UNOS update. Changes in serum chloride are commonly perceived as ‘just’ parallel to changes in serum s…
View article: External validation of the ProVent score for prognostication of 1-year mortality of critically ill patients with prolonged mechanical ventilation: a single-centre, retrospective observational study in Austria
External validation of the ProVent score for prognostication of 1-year mortality of critically ill patients with prolonged mechanical ventilation: a single-centre, retrospective observational study in Austria Open
Objectives In critically ill patients requiring mechanical ventilation for at least 21 days, 1-year mortality can be estimated using the ProVent score, calculated from four variables (age, platelet count, vasopressor use and renal replacem…
View article: Subcutaneous Enoxaparin for Systemic Anticoagulation of COVID-19 Patients During Extracorporeal Life Support
Subcutaneous Enoxaparin for Systemic Anticoagulation of COVID-19 Patients During Extracorporeal Life Support Open
Background Extracorporeal membrane oxygenation, with an inherent requirement for anticoagulation to avoid circuit thrombosis, is a key element in the treatment of respiratory failure associated with COVID-19. Anticoagulation remains challe…
View article: Clinical relevance of lung transplantation for COVID-19 ARDS: a nationwide study
Clinical relevance of lung transplantation for COVID-19 ARDS: a nationwide study Open
Background Although the number of lung transplantations (LTx) performed worldwide for coronavirus disease 2019 (COVID-19)-induced acute respiratory distress syndrome (ARDS) is still low, there is general agreement that this treatment can s…
View article: Duration of invasive mechanical ventilation prior to extracorporeal membrane oxygenation is not associated with survival in acute respiratory distress syndrome caused by coronavirus disease 2019
Duration of invasive mechanical ventilation prior to extracorporeal membrane oxygenation is not associated with survival in acute respiratory distress syndrome caused by coronavirus disease 2019 Open
Background Duration of invasive mechanical ventilation (IMV) prior to extracorporeal membrane oxygenation (ECMO) affects outcome in acute respiratory distress syndrome (ARDS). In coronavirus disease 2019 (COVID-19) related ARDS, the role o…
View article: Acute and Life-threatening Complications in Cushing Syndrome: Prevalence, Predictors, and Mortality
Acute and Life-threatening Complications in Cushing Syndrome: Prevalence, Predictors, and Mortality Open
Context Cushing syndrome (CS) results in significant morbidity and mortality. Objective To study acute and life-threatening complications in patients with active CS. Methods We performed a retrospective cohort study using inpatient and out…
View article: Prevalence and Impact of Vitamin D Deficiency in Critically Ill Cancer Patients Admitted to the Intensive Care Unit
Prevalence and Impact of Vitamin D Deficiency in Critically Ill Cancer Patients Admitted to the Intensive Care Unit Open
Vitamin D deficiency is frequent in cancer patients and a risk factor for morbidity and mortality during critical illness. This single-center retrospective study analyzed 25-hydroxyvitamin D levels in critically ill cancer patients (n = 17…
View article: Prasugrel in critically ill patients
Prasugrel in critically ill patients Open
Summary While prasugrel is indicated for the treatment of myocardial infarction, its effects in the most severely affected patients requiring intensive care is unknown, so that we measured the antiplatelet effects and sparse pharmacokineti…
View article: Acetylsalicylic acid in critically ill patients: a cross‐sectional and a randomized trial
Acetylsalicylic acid in critically ill patients: a cross‐sectional and a randomized trial Open
Background Despite decades of clinical use, the pharmacokinetics and the effects of acetylsalicylic acid ( ASA ) in critically ill patients remain ill‐defined. We aimed to investigate the pharmacokinetics and the effects of different ASA f…
View article: Outcome and features of acute kidney injury complicating hypoxic hepatitis at the medical intensive care unit
Outcome and features of acute kidney injury complicating hypoxic hepatitis at the medical intensive care unit Open
HH is frequently complicated by occurrence of AKI. Severity of HH, AKI stage and the presence of septic shock seem to contribute to poor outcome in these patients. Initiation of RRT in HH with AKI may enable renal recovery and should not b…
View article: DDRGK1 in urine indicative of tubular cell injury in intensive care patients with serious infections
DDRGK1 in urine indicative of tubular cell injury in intensive care patients with serious infections Open
C20orf116 excretion was detectable more than 24 hours before sCr rise could be measured; high level seemed to indicate severity of organ failure.