Christiane Matuschek
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View article: Assessing the quality of radiation oncology education in four German medical schools: a student perspective and comparison with DEGRO recommendations
Assessing the quality of radiation oncology education in four German medical schools: a student perspective and comparison with DEGRO recommendations Open
Purpose The increasing importance of radiation oncology (RO) education worldwide drives a need for modernization of university curricula, particularly in anticipation of the new Licensing Regulation for Physicians ( Ärztliche Approbationso…
View article: Alpha/beta values in pediatric medulloblastoma: implications for tailored approaches in radiation oncology
Alpha/beta values in pediatric medulloblastoma: implications for tailored approaches in radiation oncology Open
Background Medulloblastoma is the most common malignant pediatric brain tumor, typically treated with normofractionated craniospinal irradiation (CSI) with an additional boost over about 6 weeks in children older than 3 years. This study i…
View article: Impact of<sup>18</sup>F-FDG PET/MRI on Therapeutic Management of Women with Newly Diagnosed Breast Cancer: Results from a Prospective Double-Center Trial
Impact of<sup>18</sup>F-FDG PET/MRI on Therapeutic Management of Women with Newly Diagnosed Breast Cancer: Results from a Prospective Double-Center Trial Open
Our rationale was to investigate whether 18F-FDG PET/MRI in addition to (guideline-recommended) conventional staging leads to changes in therapeutic management in patients with newly diagnosed breast cancer and compare the diagnostic accur…
View article: First Description of Alpha/Beta Values in Pediatric Medulloblastoma: Implications for Tailored Approaches in Radiation Oncology
First Description of Alpha/Beta Values in Pediatric Medulloblastoma: Implications for Tailored Approaches in Radiation Oncology Open
Background Medulloblastoma is the most common malignant pediatric brain tumor, typically treated with normofractionated craniospinal irradiation (CSI) with an additional boost over about 6 weeks in children older than 3 years [1]. This stu…
View article: Whole Breast Irradiation in Comparison to Endocrine Therapy in Early Stage Breast Cancer—A Direct and Network Meta-Analysis of Published Randomized Trials
Whole Breast Irradiation in Comparison to Endocrine Therapy in Early Stage Breast Cancer—A Direct and Network Meta-Analysis of Published Randomized Trials Open
Background: Multiple randomized trials have established adjuvant endocrine therapy (ET) and whole breast irradiation (WBI) as the standard approach after breast-conserving surgery (BCS) in early-stage breast cancer. The omission of WBI has…
View article: Editorial: Immune response to SARS-CoV-2 and implications for clinical outcome
Editorial: Immune response to SARS-CoV-2 and implications for clinical outcome Open
EDITORIAL article Front. Immunol., 10 July 2023Sec. Viral Immunology Volume 14 - 2023 | https://doi.org/10.3389/fimmu.2023.1233291
View article: Adjuvant Therapy for Elderly Breast Cancer Patients after Breast-Conserving Surgery: Outcomes in Real World Practice
Adjuvant Therapy for Elderly Breast Cancer Patients after Breast-Conserving Surgery: Outcomes in Real World Practice Open
We aimed to evaluate the standard of care of adjuvant radiotherapy (RT) after breast-conserving surgery (BCS) in elderly female patients (≥65 years) treated outside of clinical trials and to identify potential factors related to the omissi…
View article: Percutaneous fractionated radiotherapy of the groin to eliminate lymphatic fistulas after vascular surgery
Percutaneous fractionated radiotherapy of the groin to eliminate lymphatic fistulas after vascular surgery Open
Background Vascular surgery of the inguinal area can be complicated by persistent lymphatic fistulas. Rapid and effective treatment is essential to prevent infection, sepsis, bleeding, and possible leg amputation. Current data on irradiati…
View article: Predictive Factors of Long-Term Survival after Neoadjuvant Radiotherapy and Chemotherapy in High-Risk Breast Cancer
Predictive Factors of Long-Term Survival after Neoadjuvant Radiotherapy and Chemotherapy in High-Risk Breast Cancer Open
Background: Neoadjuvant radiotherapy (naRT) in addition to neoadjuvant chemotherapy (naCT) has been used for locally advanced, inoperable breast cancer or to allow breast conserving surgery (BCS). Retrospective analyses suggest that naRT +…
View article: Early Outcome, Cosmetic Result and Tolerability of an IOERT-Boost Prior to Adjuvant Whole-Breast Irradiation
Early Outcome, Cosmetic Result and Tolerability of an IOERT-Boost Prior to Adjuvant Whole-Breast Irradiation Open
Background/Aims: Due to its favorable dose distribution and targeting of the region at highest risk of recurrence due to direct visualization of tumor bed, intraoperative electron radiation therapy (IOERT) is used as part of a breast-conse…
View article: Prognostic markers for the clinical course in the blood of patients with SARS-CoV-2 infection
Prognostic markers for the clinical course in the blood of patients with SARS-CoV-2 infection Open
Background The presentation of peptides and the subsequent immune response depend on the MHC characteristics and influence the specificity of the immune response. In addition to polymorphic T-cell receptor alpha/beta constructs, less varia…
View article: Hypofractionated Whole Breast Irradiation and Boost-IOERT in Early Stage Breast Cancer (HIOB): First Clinical Results of a Prospective Multicenter Trial (NCT01343459)
Hypofractionated Whole Breast Irradiation and Boost-IOERT in Early Stage Breast Cancer (HIOB): First Clinical Results of a Prospective Multicenter Trial (NCT01343459) Open
Background and purpose: To investigate intraoperative electron radiation therapy (IOERT) as a tumor bed boost during breast conserving surgery (BCS) followed by hypofractionated whole breast irradiation (HWBI) on age-correlated in-breast r…
View article: Post-Neoadjuvant Treatment Strategies in Breast Cancer
Post-Neoadjuvant Treatment Strategies in Breast Cancer Open
Neoadjuvant chemotherapy enables close monitoring of tumor response in patients with breast cancer. Being able to assess tumor response during treatment provides an opportunity to evaluate new therapeutic strategies. Thus, for triple-negat…
View article: Acute cardiac side effects after COVID-19 mRNA vaccination, a case series
Acute cardiac side effects after COVID-19 mRNA vaccination, a case series Open
Background: Since development and approval of the world´s first mRNA vaccines, created under pressure of the global pandemic caused by SARS-CoV-2, potential side effects have naturally been a much-debated topic. Vaccination may be one, if …
View article: Additional file 1 of Prognostic markers for the clinical course in the blood of patients with SARS-CoV-2 infection
Additional file 1 of Prognostic markers for the clinical course in the blood of patients with SARS-CoV-2 infection Open
Additional file 1: Table S1. Tests for deviation and tests for association from Hardy Weinberg equilibration.
View article: Acute cardiac side effects after COVID-19 mRNA vaccination, a case series
Acute cardiac side effects after COVID-19 mRNA vaccination, a case series Open
Background: Since development and approval of the world´s first mRNA vaccines, created under pressure of the global pandemic caused by SARS-CoV-2, potential side effects have naturally been a much-debated topic. Vaccination may be one, if …
View article: Comparison of Different Systemic Therapeutic Regimes in Resectable Soft-Tissue Sarcoma—Results of a Network Meta-Analysis
Comparison of Different Systemic Therapeutic Regimes in Resectable Soft-Tissue Sarcoma—Results of a Network Meta-Analysis Open
Background: The standard treatment of high-risk soft-tissue sarcoma consists of surgical resection followed by risk-adapted radiation therapy. Further treatment options that may improve local and systemic tumor control, including chemother…
View article: Association of HLA genotypes, AB0 blood type and chemokine receptor 5 mutant CD195 with the clinical course of COVID-19
Association of HLA genotypes, AB0 blood type and chemokine receptor 5 mutant CD195 with the clinical course of COVID-19 Open
Background COVID-19, the pandemic disease caused by infection with SARS-CoV-2, may take highly variable clinical courses, ranging from symptom-free and pauci-symptomatic to fatal disease. The goal of the current study was to assess the ass…
View article: Low-dose Radiation Treatment for Painful Heel Spur: a Highly Effective Therapy With Little Side Effects
Low-dose Radiation Treatment for Painful Heel Spur: a Highly Effective Therapy With Little Side Effects Open
Aim: Evaluation of pain reduction using orthovolt or cobalt-based radiation treatment for painful heel spurs and determination of long-term response as well as prognostic parameters. Methods: We identified a total of 102 consecutive patien…