Christie P. Thomas
YOU?
Author Swipe
View article: Hepatitis C Virus (HCV) Recurrence and Death After Viral Clearance in an HCV-Viremic Donor to HCV-Negative Kidney Recipient
Hepatitis C Virus (HCV) Recurrence and Death After Viral Clearance in an HCV-Viremic Donor to HCV-Negative Kidney Recipient Open
View article: Variants of unknown significance are common in brushite stone formers undergoing genetic testing for nephrolithiasis
Variants of unknown significance are common in brushite stone formers undergoing genetic testing for nephrolithiasis Open
View article: Educating the Next-Generation Expert in Nephrology Genetics
Educating the Next-Generation Expert in Nephrology Genetics Open
The importance of genetics and genomics in general nephrology has rapidly ascended within the last decade. While the genetic literacy of all nephrologists must improve, there is a particular need to develop the next generation of leaders a…
View article: Outcomes of High Kidney Donor Profile Index Hepatitis C Nucleic Acid Testing Positive Kidneys are Equivalent to Matched Hepatitis C Nucleic Acid Testing Negative Kidneys
Outcomes of High Kidney Donor Profile Index Hepatitis C Nucleic Acid Testing Positive Kidneys are Equivalent to Matched Hepatitis C Nucleic Acid Testing Negative Kidneys Open
Background. A recent Organ Procurement and Transplant Network policy change removes hepatitis C virus (HCV) status and race from the Kidney Donor Profile Index (KDPI) calculation, thereby lowering the KDPI of HCV nucleic acid testing posit…
View article: Heart’s secret encounter-extra skeletal Ewings sarcoma with cardiac involvement in adult: a case report
Heart’s secret encounter-extra skeletal Ewings sarcoma with cardiac involvement in adult: a case report Open
Ewing sarcoma is a rare, aggressive malignant tumour predominantly arising from bone or soft tissue in adolescents and young adults. Primary cardiac involvement is exceedingly uncommon, usually occurring as a result of metastatic spread. H…
View article: Atypical polypoid adenomyoma: insights into recurrence, malignant transformation and management: a case report
Atypical polypoid adenomyoma: insights into recurrence, malignant transformation and management: a case report Open
Atypical polypoid adenomyoma (APAM) is a rare, benign mixed epithelial-mesenchymal tumor of the uterus. It is characterized by its polypoid growth pattern and atypical histological features. This study aims to consolidate current knowledge…
View article: Kikuchi Cervical Lymhpadenitis – A Case Report
Kikuchi Cervical Lymhpadenitis – A Case Report Open
Background: Kikuchi-Fujimoto Disease (KFD), also known as Kikuchi Cervical Lymphadenitis, is a rare, benign, self-limiting condition that predominantly affects young adults, often mimicking more serious disorders such as lymphoma or tuberc…
View article: Late-onset retinal oxalosis in primary hyperoxaluria type 2
Late-onset retinal oxalosis in primary hyperoxaluria type 2 Open
View article: Screening of Living Kidney Donors for Genetic Diseases: CON
Screening of Living Kidney Donors for Genetic Diseases: CON Open
1Department of Internal Medicine and Iowa Institute of Human Genetics, University of Iowa Carver College of Medicine, Iowa City 2VA Medical Center, Iowa City, Iowa. aCorresponding author: Christie P Thomas MD, Department of Internal Medici…
View article: APOL1 Kidney Risk Variants and Long-Term Kidney Function in Healthy Middle-Aged Black Individuals: The Atherosclerosis Risk in Communities (ARIC) Study
APOL1 Kidney Risk Variants and Long-Term Kidney Function in Healthy Middle-Aged Black Individuals: The Atherosclerosis Risk in Communities (ARIC) Study Open
Among middle-aged individuals, APOL1 genotype does not appear to be a major driver of future risk of kidney disease.
View article: Homozygous missense variants in YKT6 result in loss of function and are associated with developmental delay, with or without severe infantile liver disease and risk for hepatocellular carcinoma
Homozygous missense variants in YKT6 result in loss of function and are associated with developmental delay, with or without severe infantile liver disease and risk for hepatocellular carcinoma Open
View article: A randomized controlled trial of preemptive rituximab to prevent recurrent focal segmental glomerulosclerosis post-kidney transplant (PRI-VENT FSGS): protocol and study design
A randomized controlled trial of preemptive rituximab to prevent recurrent focal segmental glomerulosclerosis post-kidney transplant (PRI-VENT FSGS): protocol and study design Open
Background Focal segmental glomerulosclerosis (FSGS) is a common cause of end-stage kidney disease requiring kidney transplantation and can recur in the allograft in 30-80% of recipients resulting in reduced graft survival. Plasmapheresis …
View article: Managing the Costs of Routine Follow-up Care After Living Kidney Donation: a Review and Survey of Contemporary Experience, Practices, and Challenges
Managing the Costs of Routine Follow-up Care After Living Kidney Donation: a Review and Survey of Contemporary Experience, Practices, and Challenges Open
Purpose of Review While living organ donor follow-up is mandated for 2 years in the USA, formal guidance on recovering associated costs of follow-up care is lacking. In this review, we discuss current billing practices of transplant progra…
View article: New KCNN4 Variants Associated With Anemia: Stomatocytosis Without Erythrocyte Dehydration
New KCNN4 Variants Associated With Anemia: Stomatocytosis Without Erythrocyte Dehydration Open
The K + channel activated by the Ca 2+ , KCNN4, has been shown to contribute to red blood cell dehydration in the rare hereditary hemolytic anemia, the dehydrated hereditary stomatocytosis. We report two de novo mutations on KCNN4 , We rep…
View article: Monogenic focal segmental glomerulosclerosis: A conceptual framework for identification and management of a heterogeneous disease
Monogenic focal segmental glomerulosclerosis: A conceptual framework for identification and management of a heterogeneous disease Open
Focal segmental glomerulosclerosis (FSGS) is not a disease, rather a pattern of histological injury occurring from a variety of causes. The exact pathogenesis has yet to be fully elucidated but is likely varied based on the type of injury …
View article: Case Report: Severe COVID-19 in a Kidney Transplant Recipient Without Humoral Response to SARS-CoV-2 mRNA Vaccine Series
Case Report: Severe COVID-19 in a Kidney Transplant Recipient Without Humoral Response to SARS-CoV-2 mRNA Vaccine Series Open
Supplemental Digital Content is available in the text.
View article: Integrating APOL1 Kidney-risk Variant Testing in Live Kidney Donor Evaluation: An Expert Panel Opinion
Integrating APOL1 Kidney-risk Variant Testing in Live Kidney Donor Evaluation: An Expert Panel Opinion Open
INTRODUCTION Live kidney donors (LKDs) of African ancestry have a higher risk for developing end-stage kidney disease (ESKD) than demographically matched healthy nondonors.1 Retrospective data from the general population reveal that having…
View article: Correction: Initial experience from a renal genetics clinic demonstrates a distinct role in patient management
Correction: Initial experience from a renal genetics clinic demonstrates a distinct role in patient management Open
View article: Minimal Change Disease With Nephrotic Syndrome Associated With Coronavirus Disease 2019 After Apolipoprotein L1 Risk Variant Kidney Transplant: A Case Report
Minimal Change Disease With Nephrotic Syndrome Associated With Coronavirus Disease 2019 After Apolipoprotein L1 Risk Variant Kidney Transplant: A Case Report Open
View article: Donor-derived human herpesvirus 8 and development of Kaposi sarcoma among 6 recipients of organs from donors with high-risk sexual and substance use behavior
Donor-derived human herpesvirus 8 and development of Kaposi sarcoma among 6 recipients of organs from donors with high-risk sexual and substance use behavior Open
View article: A rare case of hyporeninemic hypertension: Answers
A rare case of hyporeninemic hypertension: Answers Open
View article: A rare case of hyporeninemic hypertension: Questions
A rare case of hyporeninemic hypertension: Questions Open
View article: Initial experience from a renal genetics clinic demonstrates a distinct role in patient management
Initial experience from a renal genetics clinic demonstrates a distinct role in patient management Open
View article: Unexpected Race and Ethnicity Differences in the US National Veterans Affairs Kidney Transplant Program
Unexpected Race and Ethnicity Differences in the US National Veterans Affairs Kidney Transplant Program Open
Background. Racial/ethnic minorities have lower rates of deceased kidney transplantation (DDKT) and living donor kidney transplantation (LDKT) in the United States. We examined whether social determinants of health (eg, demographics, cultu…
View article: Targeted broad-based genetic testing by next-generation sequencing informs diagnosis and facilitates management in patients with kidney diseases
Targeted broad-based genetic testing by next-generation sequencing informs diagnosis and facilitates management in patients with kidney diseases Open
Background The clinical diagnosis of genetic renal diseases may be limited by the overlapping spectrum of manifestations between diseases or by the advancement of disease where clues to the original process are absent. The objective of thi…
View article: The Future of Cataloging in a FOLIO Environment
The Future of Cataloging in a FOLIO Environment Open
"The Future of Libraries Is Open" (FOLIO) is a community-driven effort to develop an open source library services platform. This article introduces the FOLIO community, provides background on the University of Chicago's involvement with th…
View article: Billing for Living Kidney Donor Care: Balancing Cost Recovery, Regulatory Compliance, and Minimized Donor Burden
Billing for Living Kidney Donor Care: Balancing Cost Recovery, Regulatory Compliance, and Minimized Donor Burden Open
View article: Genetic Analysis of 400 Patients Refines Understanding and Implicates a New Gene in Atypical Hemolytic Uremic Syndrome
Genetic Analysis of 400 Patients Refines Understanding and Implicates a New Gene in Atypical Hemolytic Uremic Syndrome Open
Background Genetic variation in complement genes is a predisposing factor for atypical hemolytic uremic syndrome (aHUS), a life-threatening thrombotic microangiopathy, however interpreting the effects of genetic variants is challenging and…
View article: VEGF-A selectively inhibits FLT1 ectodomain shedding independent of receptor activation and receptor endocytosis
VEGF-A selectively inhibits FLT1 ectodomain shedding independent of receptor activation and receptor endocytosis Open
Ectodomain shedding and regulated intracellular proteolysis can determine the fate or function of cell surface proteins. Fms-related tyrosine kinase (FLT) or VEGF receptor 1 is a high-affinity cell surface VEGF-A receptor tyrosine kinase t…
View article: EGF regulation of proximal tubule cell proliferation and VEGF-A secretion
EGF regulation of proximal tubule cell proliferation and VEGF-A secretion Open
Proximal tubule cell (PTC) proliferation is critical for tubular regeneration and recovery from acute kidney injury. Epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF-A) are important for the maintenance of tubuloi…