Christina Easter
YOU?
Author Swipe
View article: Clinical care processes for early postpartum haemorrhage diagnosis: a nested observational study within the E-MOTIVE trial
Clinical care processes for early postpartum haemorrhage diagnosis: a nested observational study within the E-MOTIVE trial Open
Background Postpartum haemorrhage (PPH) is the leading cause of maternal mortality, particularly in low- and- middle-income countries. The E-MOTIVE trial demonstrated a 60% reduction in severe PPH and related complications with the E-MOTIV…
View article: Researchers’ views of risk of bias in cluster randomised trials: a qualitative interview study
Researchers’ views of risk of bias in cluster randomised trials: a qualitative interview study Open
Objectives Cluster randomised trials (CRTs) can be at risk of bias driven by differential identification and recruitment of participants across treatments, posing a threat to the validity of findings. We explored the awareness and importan…
View article: When are postpartum haemorrhages diagnosed? A nested observational study within the E-MOTIVE cluster-randomised trial
When are postpartum haemorrhages diagnosed? A nested observational study within the E-MOTIVE cluster-randomised trial Open
Bill & Melinda Gates Foundation and Ammalife.
View article: When Is Postpartum Haemorrhage Treatment Initiated? A Nested Observational Study Within the E‐MOTIVE Trial
When Is Postpartum Haemorrhage Treatment Initiated? A Nested Observational Study Within the E‐MOTIVE Trial Open
Objective To compare the frequency and timing of postpartum haemorrhage (PPH) treatment initiation between hospitals implementing the MOTIVE treatment bundle (which consisted of uterine Massage, Oxytocic drugs, Tranexamic acid, IntraVenous…
View article: Surgery on the aortic arch and feasibility of electroencephalography (SAFE) monitoring in neonates: protocol for a prospective observational cohort study
Surgery on the aortic arch and feasibility of electroencephalography (SAFE) monitoring in neonates: protocol for a prospective observational cohort study Open
Introduction While survival rates following neonatal surgery for congenital heart disease (CHD) have improved over the years, neurodevelopmental delays are still highly prevalent in these patients. After correcting for the CHD subtype, the…
View article: An exploration of sub-national variability in institutional maternal mortality ratios in Kenya: a meta-analysis of the 2021 health facility data
An exploration of sub-national variability in institutional maternal mortality ratios in Kenya: a meta-analysis of the 2021 health facility data Open
Background In many countries in sub-Saharan Africa, the burden of preventable maternal deaths is still unacceptably high. Most Maternal Mortality Ratio (MMR) estimates are national, rarely sub-national. This study explores Kenya's 2021 nat…
View article: The Association Between Periconceptual Maternal Dietary Patterns and Miscarriage Risk in Women With Recurrent Miscarriages: A Multicentre Cohort Study
The Association Between Periconceptual Maternal Dietary Patterns and Miscarriage Risk in Women With Recurrent Miscarriages: A Multicentre Cohort Study Open
Objective To examine the association between periconceptual maternal diet and miscarriage risk among women with recurrent miscarriages. Design Prospective multicentre cohort study (Tommy's Net). Setting Three university hospital research c…
View article: The association between periconceptual maternal dietary patterns and miscarriage risk in women with recurrent miscarriages: a multicentre cohort study
The association between periconceptual maternal dietary patterns and miscarriage risk in women with recurrent miscarriages: a multicentre cohort study Open
In a prospective multicentre cohort study across three UK university hospital research centres, we evaluated the association between periconceptual maternal dietary patterns and miscarriage risk among 1,035 women with recurrent miscarriage…
View article: Objective Measurement of Blood Loss following Vaginal Delivery in a UK Hospital
Objective Measurement of Blood Loss following Vaginal Delivery in a UK Hospital Open
Background: Postpartum haemorrhage (PPH) is the leading cause of maternal morbidity and mortality worldwide. The reported incidence of PPH varies globally, which is often due to the use of subjective visual estimation of blood loss. The ai…
View article: P-546 History of caesarean births and risk of miscarriage - secondary analysis of three randomised controlled trials
P-546 History of caesarean births and risk of miscarriage - secondary analysis of three randomised controlled trials Open
Study question Does the history of caesarean births influence miscarriage risk in subsequent pregnancies? Summary answer In women with a history of 3 or more miscarriage(s), the subsequent miscarriage risk may increase with the presence an…
View article: Prevalence of adenomyosis in women with subfertility: systematic review and meta‐analysis
Prevalence of adenomyosis in women with subfertility: systematic review and meta‐analysis Open
Objective To determine the prevalence of adenomyosis in women with subfertility. Methods A systematic search was conducted in MEDLINE, EMBASE, CINAHL Plus, Google Scholar, PsycINFO and Web of Science Core Collection from database inception…
View article: P-350 Endometrial receptivity analysis (ERA) and microbiome testing for recurrent implantation failure (RIF): a matched case control study
P-350 Endometrial receptivity analysis (ERA) and microbiome testing for recurrent implantation failure (RIF): a matched case control study Open
Study question Does the use of ERA, EMMA (endometrial microbiome metogenomic analysis) or ALICE (analysis of infectious chronic endometritis) improve implantation rate and clinical pregnancy? Summary answer The use of ERA significantly imp…
View article: Morphological and morphokinetic associations with aneuploidy: a systematic review and meta-analysis
Morphological and morphokinetic associations with aneuploidy: a systematic review and meta-analysis Open
BACKGROUND A time lapse system (TLS) is utilized in some fertility clinics with the aim of predicting embryo viability and chance of live birth during IVF. It has been hypothesized that aneuploid embryos display altered morphokinetics as a…
View article: Risk of Bias in Cluster Randomised Controlled Trials of Individual-Level Interventions: Protocol for a Semi-Structured Interview Study
Risk of Bias in Cluster Randomised Controlled Trials of Individual-Level Interventions: Protocol for a Semi-Structured Interview Study Open
Background Many cluster randomised trials of individual-level interventions are at risk of bias, mostly due to identification and recruitment biases, which would not feature under individual randomisation. This bias arises when participant…
View article: Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT
Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT Open
BACKGROUND: Daily assessment of patient readiness for liberation from invasive mechanical ventilation can reduce the duration of ventilation. However, there is uncertainty about the effectiveness of this in a paediatric population.
\n
\nO…
View article: The effect of frozen embryo transfer regimen on the association between serum progesterone and live birth: a multicentre prospective cohort study (ProFET)
The effect of frozen embryo transfer regimen on the association between serum progesterone and live birth: a multicentre prospective cohort study (ProFET) Open
STUDY QUESTION What is the association between serum progesterone levels on the day of frozen embryo transfer (FET) and the probability of live birth in women undergoing different FET regimens? SUMMARY ANSWER Overall, serum progesterone le…
View article: Placental growth factor in assessment of women with suspected pre-eclampsia to reduce maternal morbidity: a stepped wedge cluster randomised control trial (PARROT Ireland)
Placental growth factor in assessment of women with suspected pre-eclampsia to reduce maternal morbidity: a stepped wedge cluster randomised control trial (PARROT Ireland) Open
Objective To determine whether the addition of placental growth factor (PlGF) measurement to current clinical assessment of women with suspected pre-eclampsia before 37 weeks' gestation would reduce maternal morbidity without increasing ne…
View article: Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units
Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units Open
isrctn.org Identifier: ISRCTN16998143.
View article: Looking at knock‐on effects: univariable, multivariable linear regression
Looking at knock‐on effects: univariable, multivariable linear regression Open
Linear regression is used to describe the association between a continuous dependent variable of interest (outcome) and other patient characteristics or predictors (independent continuous, categorical or dichotomous variables). Fitting a l…
View article: What are the odds?
What are the odds? Open
A case–control study used logistic regression to examine factors associated with maternal death due to direct pregnancy complications using 14 previously identified risk factors (Nair et al. BJOG 2015;122:653–62). In a univariable analysis…
View article: Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference
Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference Open
Aims The risk of developing atrial fibrillation (AF) and its complications continues to increase, despite good progress in preventing AF-related strokes. Methods and results This article summarizes the outcomes of the 7th Consensus Confere…
View article: Development and external validation of predictive models for prevalent and recurrent atrial fibrillation: a protocol for the analysis of the CATCH ME combined dataset
Development and external validation of predictive models for prevalent and recurrent atrial fibrillation: a protocol for the analysis of the CATCH ME combined dataset Open
This retrospective, harmonised, individual patient data analysis will use information from 12 datasets collected in five European countries. It is envisioned that the outcome of this analysis would provide a greater understanding of the fa…
View article: Effectiveness of a brief behavioural intervention to prevent weight gain over the Christmas holiday period: randomised controlled trial
Effectiveness of a brief behavioural intervention to prevent weight gain over the Christmas holiday period: randomised controlled trial Open
Objective To test the effectiveness of a brief behavioural intervention to prevent weight gain over the Christmas holiday period. Design Two group, double blinded randomised controlled trial. Setting Recruitment from workplaces, social med…
View article: Quality of stepped-wedge trial reporting can be reliably assessed using an updated CONSORT: crowd-sourcing systematic review
Quality of stepped-wedge trial reporting can be reliably assessed using an updated CONSORT: crowd-sourcing systematic review Open
When reporting SW-CRTs, authors should pay particular attention to ensure clear reporting on the exact format of the design with justification, as well as how clusters and individuals were identified for inclusion in the study, and whether…