Christina Ekstrand
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View article: SUN-565 High-dimensional Immunophenotyping of Immune Checkpoint Inhibitor-Induced Type 1 Diabetes
SUN-565 High-dimensional Immunophenotyping of Immune Checkpoint Inhibitor-Induced Type 1 Diabetes Open
Disclosure: Z. Quandt: None. S. Yellamilli: None. E. Flynn: None. V. Johri: None. B. Davidson: None. J. Tsui: None. A. Combes: None. G. Fragiadakis: None. A. Young: None. M. Anderson: None. Introduction: Immune checkpoint inhibitor (ICI) t…
View article: Persistent and progressive acute lung allograft dysfunction is linked to cell compositional and transcriptional changes in small airways
Persistent and progressive acute lung allograft dysfunction is linked to cell compositional and transcriptional changes in small airways Open
In this pilot study, persistent and progressive ALAD was associated with changes in bronchiolar cell composition and transcriptional programs. Molecular phenotyping may help identify and characterize individuals with ALAD at increased risk…
View article: Coordinated variation in the immune systems and microbiomes of healthy humans is linked to tonic interferon states
Coordinated variation in the immune systems and microbiomes of healthy humans is linked to tonic interferon states Open
Human immune systems are highly variable, with most variation attributable to non-genetic sources. The gut microbiome crucially shapes the immune system; however, its relationship with the baseline immune states of healthy humans remains i…
View article: Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networks
Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networks Open
Background & Aims Imaging-based, single-cell spatial transcriptomics (iSCST) using formalin-fixed, paraffin-embedded (FFPE) tissue could transform translational research by retaining all tissue cell subsets and spatial locations while enab…
View article: Chromatin remodelling drives immune cell–fibroblast communication in heart failure
Chromatin remodelling drives immune cell–fibroblast communication in heart failure Open
View article: Macrophage and CD8 T cell discordance are associated with acute lung allograft dysfunction progression
Macrophage and CD8 T cell discordance are associated with acute lung allograft dysfunction progression Open
View article: Single-Cell Spatial Transcriptomics of Fixed, Paraffin-Embedded Biopsies Reveals Colitis-Associated Cell Networks
Single-Cell Spatial Transcriptomics of Fixed, Paraffin-Embedded Biopsies Reveals Colitis-Associated Cell Networks Open