Christina M. Robinson
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View article: Improving Colorectal Cancer Screening and Risk Assessment through Predictive Modeling on Medical Images and Records
Improving Colorectal Cancer Screening and Risk Assessment through Predictive Modeling on Medical Images and Records Open
Colonoscopy screening effectively identifies and removes polyps before they progress to colorectal cancer (CRC), but current follow-up guidelines rely primarily on histopathologic features, overlooking other important CRC risk factors. Var…
View article: A CSF-1R inhibitor both prevents and treats triple-negative breast cancer brain metastases in hematogenous preclinical models
A CSF-1R inhibitor both prevents and treats triple-negative breast cancer brain metastases in hematogenous preclinical models Open
View article: BSLM-11 ESTABLISHING AND VALIDATING IN VIVO MODELS FOR LEPTOMENINGEAL METASTASES IN BREAST CANCER: INSIGHTS AND THERAPEUTIC IMPLICATIONS
BSLM-11 ESTABLISHING AND VALIDATING IN VIVO MODELS FOR LEPTOMENINGEAL METASTASES IN BREAST CANCER: INSIGHTS AND THERAPEUTIC IMPLICATIONS Open
Leptomeningeal metastases (LM), characterized by cancer cell growth in the linings of the brain and spinal cord, and the cerebrospinal fluid (CSF) compartment, have a dire prognosis represent 5-15% of central nervous system metastases. LM …
View article: Association between Colonoscopy Sedation Type and Polyp Detection: A Registry-based Cohort Study
Association between Colonoscopy Sedation Type and Polyp Detection: A Registry-based Cohort Study Open
Background Colorectal cancer is a leading cause of cancer-related death. Adenomas and serrated polyps are precursors of colorectal cancer, with serrated polyps being more difficult to detect during colonoscopy. The relationship between pro…
View article: Prevalence of neoplasia at colonoscopy among testicular cancer survivors treated with platinum‐based chemotherapy
Prevalence of neoplasia at colonoscopy among testicular cancer survivors treated with platinum‐based chemotherapy Open
Testicular cancer survivors (TCS) treated with platinum‐based chemotherapy have an increased risk of colorectal cancer (CRC). We determined the yield of colonoscopy in TCS to assess its potential in reducing CRC incidence and mortality. We…
View article: A-110 Analytical Performance Evaluation of Diazo Bilirubin Assays on the Atellica CH Analyzer
A-110 Analytical Performance Evaluation of Diazo Bilirubin Assays on the Atellica CH Analyzer Open
Background Measurements of bilirubin are used to evaluate liver function. The two most common methods to measure bilirubin are the diazo method (based on measuring the color of azobilirubin) and the vanadate method (based on chemical oxida…
View article: Higher Serrated Polyp Detection Rates Are Associated With Lower Risk of Postcolonoscopy Colorectal Cancer: Data From the New Hampshire Colonoscopy Registry
Higher Serrated Polyp Detection Rates Are Associated With Lower Risk of Postcolonoscopy Colorectal Cancer: Data From the New Hampshire Colonoscopy Registry Open
INTRODUCTION: We used New Hampshire Colonoscopy Registry data to examine the association between postcolonoscopy colorectal cancer (PCCRC) and sessile serrated detection rates (SSLDRs). METHODS: We included patients with either a colonosco…
View article: What do ‘false-positive’ stool tests really mean? Data from the New Hampshire colonoscopy registry
What do ‘false-positive’ stool tests really mean? Data from the New Hampshire colonoscopy registry Open
View article: Supplementary Table from Colonoscopy Findings in FIT<sup>+</sup> and mt-sDNA<sup>+</sup> Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data
Supplementary Table from Colonoscopy Findings in FIT<sup>+</sup> and mt-sDNA<sup>+</sup> Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data Open
Supplementary Table from Colonoscopy Findings in FIT+ and mt-sDNA+ Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data
View article: Supplementary Data from Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma
Supplementary Data from Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma Open
Supplemental tables 1-3, supplemental figure legends, supplemental figures 1-4
View article: Supplementary Tables from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin
Supplementary Tables from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin Open
Supplementary Tables
View article: Supplementary Table from Colonoscopy Findings in FIT<sup>+</sup> and mt-sDNA<sup>+</sup> Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data
Supplementary Table from Colonoscopy Findings in FIT<sup>+</sup> and mt-sDNA<sup>+</sup> Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data Open
Supplementary Table from Colonoscopy Findings in FIT+ and mt-sDNA+ Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data
View article: Supplementary Figure S8.1 from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin
Supplementary Figure S8.1 from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin Open
Uncropped immunoblots reported in this study.
View article: Supplementary Movie 1 from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin
Supplementary Movie 1 from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin Open
Supplementary Movie depicting the proposed mechanism through which amplified TNIK contributes to LSCC cell viability
View article: Supplementary Figures from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin
Supplementary Figures from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin Open
Supplementary Figures S1-S7
View article: Supplementary Methods from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin
Supplementary Methods from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin Open
Supplementary Methods
View article: Supplementary Movie 1 from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin
Supplementary Movie 1 from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin Open
Supplementary Movie depicting the proposed mechanism through which amplified TNIK contributes to LSCC cell viability
View article: Data from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin
Data from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin Open
Lung squamous cell carcinoma (LSCC) is the second most prevalent type of lung cancer. Despite extensive genomic characterization, no targeted therapies are approved for the treatment of LSCC. Distal amplification of the 3q chromosome is th…
View article: Supplementary Figure S8.2 from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin
Supplementary Figure S8.2 from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin Open
Uncropped immunoblots reported in this study.
View article: Data from Colonoscopy Findings in FIT<sup>+</sup> and mt-sDNA<sup>+</sup> Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data
Data from Colonoscopy Findings in FIT<sup>+</sup> and mt-sDNA<sup>+</sup> Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data Open
Few studies compare fecal immunochemical test (FIT) and multi-target stool DNA (mt-sDNA) outcomes in practice. We compared colonoscopy yield following FIT+ or mt-sDNA+ tests to colonoscopies without preceding stool te…
View article: Supplementary Figure S8.1 from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin
Supplementary Figure S8.1 from TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin Open
Uncropped immunoblots reported in this study.
View article: Data from Colonoscopy Findings in FIT<sup>+</sup> and mt-sDNA<sup>+</sup> Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data
Data from Colonoscopy Findings in FIT<sup>+</sup> and mt-sDNA<sup>+</sup> Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data Open
Few studies compare fecal immunochemical test (FIT) and multi-target stool DNA (mt-sDNA) outcomes in practice. We compared colonoscopy yield following FIT+ or mt-sDNA+ tests to colonoscopies without preceding stool te…
View article: Data from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis
Data from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis Open
Purpose:Breast cancer diagnosed in young patients is often aggressive. Because primary breast tumors from young and older patients have similar mutational patterns, we hypothesized that the young host microenvironment promotes more aggress…
View article: Supplementary Figures from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis
Supplementary Figures from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis Open
Supplementary Figures
View article: Supplementary Figures from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis
Supplementary Figures from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis Open
Supplementary Figures
View article: Supplementary Methods from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis
Supplementary Methods from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis Open
Supplementary Methods
View article: Supplementary Table 1 from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis
Supplementary Table 1 from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis Open
Supplementary Table 1
View article: Supplementary Methods from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis
Supplementary Methods from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis Open
Supplementary Methods
View article: Supplementary Table 1 from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis
Supplementary Table 1 from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis Open
Supplementary Table 1
View article: Data from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis
Data from Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis Open
Purpose:Breast cancer diagnosed in young patients is often aggressive. Because primary breast tumors from young and older patients have similar mutational patterns, we hypothesized that the young host microenvironment promotes more aggress…