Explanipedia

High-Frequency Quantitative Ultrasound Elastography for the Mechanical Assessment of Thin Biomaterials In Vitro Open

Joseph A. Sebastian, Emmanuel Chérin, Eric M. Strohm, Zach Gouveia, Aaron Boyes , et al. · 2025

Etv5 Is Required for Peripheral Nerve Function and the Injury Response Open

Lauren Belfiore, Anjali Balakrishnan, Yohannes Soenjaya, Hussein Ghazale, Alexandra Moffat , et al. · 2025

The development of Schwann cells, which myelinate axons in the peripheral nervous system, is critically dependent on MEK/ERK signaling. While Ets-domain transcription factors ( Etv1 , Etv4 , Etv5 ) are downstream effectors of this pathway,…

Side-Illuminating Optical Fiber for High-Power-Density-Mediated Intraluminal Photoacoustic Imaging Open

Nidhi Singh, Carlos-Felipe Roa, Emmanuel Chérin, Lothar Lilge, Christine Démoré · 2025

Intraluminal photoacoustic (PA) imaging has the potential for providing physiological and functional information in wide-ranging clinical applications. Along with endoluminal ultrasound transducers, these applications require compact light…

Development of a Small-Footprint 50 MHz Linear Array: Fabrication and Micro-Ultrasound Imaging Demonstration Open

Carlos-Felipe Roa, Emmanuel Chérin, Nidhi Singh, Jianhua Yin, Aaron Boyes , et al. · 2024

Compact high-frequency arrays are of interest for clinical and preclinical applications in which a small-footprint or endoscopic device is needed to reach the target anatomy. However, the fabrication of compact arrays entails the connectio…

Micro-ultrasound based characterization of cerebrovasculature following focal ischemic stroke and upon short-term rehabilitation Open

Johnson Yu, Illsung L. Joo, Paolo Bazzigaluppi, Margaret M. Koletar, Emmanuel Chérin , et al. · 2023

Notwithstanding recanalization treatments in the acute stage of stroke, many survivors suffer long-term impairments. Physical rehabilitation is the only widely available strategy for chronic-stage recovery, but its optimization is hindered…

Imaging Microbubbles With Contrast-Enhanced Endobronchial Ultrasound Open

Sean McGrath, Yu-Jack Shen, Masato Aragaki, Yamato Motooka, T. Koga , et al. · 2023

Superharmonic and Microultrasound Imaging With Plane Wave Beamforming Techniques Open

Jing Yang, Emmanuel Chérin, Jianhua Yin, Paul A. Dayton, F. Stuart Foster , et al. · 2023

Superharmonic contrast imaging (SpHI) suppresses tissue clutter and allows high-contrast visualization of the vasculature. An array-based dual-frequency (DF) probe has been developed for SpHI, integrating a 21-MHz, 256-element microultraso…

High-frequency quantitative ultrasound to assess the acoustic properties of engineered tissues in vitro Open

Joseph A. Sebastian, Eric M. Strohm, Emmanuel Chérin, Bahram Mirani, Christine Démoré , et al. · 2022

Acoustic properties of biomaterials and engineered tissues reflect their structure and cellularity. High-frequency ultrasound (US) can non-invasively characterize and monitor these properties with sub-millimetre resolution. We present an a…

Sebastian+Simmons-High-frequency quantitative ultrasound to assess the acoustic properties of engineered tissues in vitro Open

Joseph Sebastian, Eric M. Strohm, Emmanuel Chérin, Bahram Mirani, Christine Démoré , et al. · 2022

This dataset includes raw acquired ultrasound data, processing scripts, and statistical data for acoustic property characterization of cell-free and cell-seeded fibrin hydrogels.

Progress towards wafer-scale fabrication based on gel casting technique for 1–3 randomised piezocomposite μUS linear array Open

Arjin Boonruang, Tanikan Thongchai, Yun Jiang, Christine Démoré, S. Neale , et al. · 2022

Microultrasound (μUS) linear arrays operating at frequencies over 25 MHz have applications in high resolution biomedical imaging. 1–3 connectively piezoceramic – polymer composite (“piezocomposite”) material is attractive for fabrication o…

Acoustic Molecular Imaging Beyond the Diffraction Limit In Vivo Open

Thomas M. Kierski, Rachel W. Walmer, James K. Tsuruta, Jianhua Yin, Emmanuel Chérin , et al. · 2022

Ultrasound molecular imaging (USMI) is a technique used to noninvasively estimate the distribution of molecular markers in vivo by imaging microbubble contrast agents (MCAs) that have been modified to target receptors of interest on…

Real-time visualisation of peripheral nerve trauma during subepineural injection in pig brachial plexus using micro-ultrasound Open

Anu Chandra, Yohannes Soenjaya, Judy Yan, Paul A. Felts, Graeme McLeod , et al. · 2021

Implementation of a Novel 288-Element Dual-Frequency Array for Acoustic Angiography: In Vitro and In Vivo Characterization Open

Isabel G. Newsome, Thomas M. Kierski, Guofeng Pang, Jianhua Yin, Jing Yang , et al. · 2021

Acoustic angiography is a superharmonic contrast-enhanced ultrasound imaging method that produces high-resolution, 3-D maps of the microvasculature. Previous acoustic angiography studies have used twoelement, annular,mechanicallyactuated t…

A novel, hands-free ultrasound patch for continuous monitoring of quantitative Doppler in the carotid artery Open

Jon‐Émile S. Kenny, Chelsea E. Munding, Joseph K. Eibl, Andrew M. Eibl, Bradley F. Long , et al. · 2021

Characterization of an Array-Based Dual-Frequency Transducer for Superharmonic Contrast Imaging Open

Jing Yang, Emmanuel Chérin, Jianhua Yin, Isabel G. Newsome, Thomas M. Kierski , et al. · 2021

Superharmonic imaging with dual-frequency imaging systems uses conventional low-frequency ultrasound transducers on transmit, and high-frequency transducers on receive to detect higher order harmonic signals from microbubble contrast agent…

High-Frequency Array-Based Nanobubble Nonlinear Imaging in a Phantom and In Vivo Open

Carly Pellow, Emmanuel Chérin, Eric Abenojar, Agata A. Exner, Gang Zheng , et al. · 2021

There has been growing interest in nanobubbles (NBs) for vascular and extravascular ultrasound contrast imaging and therapeutic applications. Studies to date have generally utilized low frequencies (10⁹ mL^-1), and unc…

Superharmonic Ultrasound for Motion-Independent Localization Microscopy: Applications to Microvascular Imaging From Low to High Flow Rates Open

Thomas M. Kierski, David Espíndola, Isabel G. Newsome, Emmanuel Chérin, Jianhua Yin , et al. · 2020

Recent advances in high frame rate biomedical ultrasound have led to the development of ultrasound localization microscopy (ULM), a method of imaging microbubble (MB) contrast agents beyond the diffraction limit of conventional coherent im…

Transcranial Photoacoustic Detection of Blood-Brain Barrier Disruption Following Focused Ultrasound-Mediated Nanoparticle Delivery Open

Johann Le Floc’h, Hoang D. Lu, Tristan Lim, Christine Démoré, Robert K. Prud’homme , et al. · 2019

In Vitro Superharmonic Contrast Imaging Using a Hybrid Dual-Frequency Probe Open

Emmanuel Chérin, Jianhua Yin, Alex Forbrich, Christopher White, Paul A. Dayton , et al. · 2019

Acoustic protein nanostructures for contrast ultrasound Open

F. Stuart Foster, Judy Yan, Yohannes Soenjaya, Christine Démoré · 2019

Design and Simulation of a Ring-Shaped Linear Array for Microultrasound Capsule Endoscopy Open

Holly S. Lay, Benjamin F. Cox, Vipin Seetohul, Christine Démoré, S. Cochran · 2018

Video capsule endoscopy (VCE) has significantly advanced visualization of the gastrointestinal tract since its introduction in the last 20 years. Work is now under way to combine VCE with microultrasound imaging. However, small maximum cap…

Optically enhanced acoustophoresis Open

Michael P. MacDonald, Craig McDougall, Paul O’Mahoney, Yongqiang Qiu, Alan McGuinn , et al. · 2017

Regenerative medicine has the capability to revolutionise many aspects of medical care, but for it to make the step from small scale autologous treatments to larger scale allogeneic approaches, robust and scalable label free cell sorting t…

Microultrasound characterisation of ex vivo porcine tissue for ultrasound capsule endoscopy Open

Holly S. Lay, Benjamin F. Cox, Mohammed R. S. Sunoqrot, Christine Démoré, Inke Näthke , et al. · 2017

Gastrointestinal (GI) disease development and progression is often characterised by cellular and tissue architectural changes within the mucosa and sub-mucosa layers. Current clinical capsule endoscopy and other approaches are heavily reli…

The feasibility of micro‐ultrasound as a tool to image peripheral nerves Open

Anu Chandra, Roos Eisma, Paul A. Felts, S. Munirama, George Corner , et al. · 2016

Summary Despite widespread use of ultrasound imaging to guide needle placement, the incidence of transient and permanent nerve damage as a complication of regional anaesthesia has not changed over the last decade. In view of the controvers…

Sonopill: A Platform for Gastrointestinal Disease Diagnosis and Therapeutics Open

Gerard Cummins, Marc P. Y. Desmulliez, David E. Watson, Vasileios Mitrakos, Julia Faerber , et al. · 2016

Progress towards a multi-modal capsule endoscopy device featuring microultrasound imaging Open

Holly S. Lay, Yongqiang Qiu, Mohammed A. Al-Rawhani, James Beeley, Romans Poltarjonoks , et al. · 2016

Current clinical standards for endoscopy in the gastrointestinal (GI) tract combine high definition optics and ultrasound imaging to view the lumen superficially and through its thickness. However, these instruments are limited to the leng…

Intraoperative Ultrasound-Guided Resection of Gliomas: A Meta-Analysis and Review of the Literature Open

Syed Mahboob, Rachael McPhillips, Zhen Qiu, Yun Jiang, C. Meggs , et al. · 2016

Implementation of a PMN-PT piezocrystal-based focused array with geodesic faceted structure Open

Zhen Qiu, Yongqiang Qiu, Christine Démoré, S. Cochran · 2016

A highly compact packaging concept for ultrasound transducer arrays embedded in neurosurgical needles Open

Giuseppe Schiavone, Thomas Jones, Dennis Price, Rachael McPhillips, Yun Jiang , et al. · 2016

State-of-the-art neurosurgery intervention relies heavily on information from tissue imaging taken at a pre-operative stage. However, the data retrieved prior to performing an opening in the patient’s skull may present inconsistencies with…

Sonopill Pathfinder: Rapid Prototyping for Ultrasound Capsule Endoscopy Open

Gerard Cummins, Marc P. Y. Desmulliez, Duncan P. Hand, Krystian L. Wlodarczyk, Christine Démoré , et al. · 2016

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