Christine L. Chan
YOU?
Author Swipe
View article: The ‘Swipe’ Technique for Prostatic Urethral Lift (PUL): A Comparative Analysis of 200 Patients in A Prospective Cohort
The ‘Swipe’ Technique for Prostatic Urethral Lift (PUL): A Comparative Analysis of 200 Patients in A Prospective Cohort Open
View article: MON-596 Evaluation of Continuous Glucose Monitoring Thresholds for Diabetes Screening in Cystic Fibrosis: Insights from the EnVision-Glucose Tolerance Study
MON-596 Evaluation of Continuous Glucose Monitoring Thresholds for Diabetes Screening in Cystic Fibrosis: Insights from the EnVision-Glucose Tolerance Study Open
Disclosure: Z.V. Hurt: None. T. Vigers: None. A. Granados: None. A. Moheet: None. K. Larson Ode: None. C.L. Chan: None. Continuous glucose monitoring (CGM) is increasingly used in cystic fibrosis (CF) to aid cystic fibrosis related diabete…
View article: SAT-732 Longitudinal Changes in Bone Mineral Density After Initiation of Elexacaftor-Tezacaftor-Ivacaftor in Youth and Adults with Cystic Fibrosis
SAT-732 Longitudinal Changes in Bone Mineral Density After Initiation of Elexacaftor-Tezacaftor-Ivacaftor in Youth and Adults with Cystic Fibrosis Open
Disclosure: M. Shirley Bezerra: None. B. Zemel: None. R.J. Gallop: None. R. Walega: None. S. Schwarzenberg: None. S.D. Freedman: None. G.M. Solomon: None. C.L. Chan: None. A. Kelly: None. Context: Low bone mineral density (BMD) and increas…
View article: Cystic Fibrosis-Related Diabetes
Cystic Fibrosis-Related Diabetes Open
Cystic fibrosis-related diabetes (CFRD) is an increasingly prevalent complication of cystic fibrosis (CF), as people with CF live longer particularly in the era of cystic fibrosis transmembrane conductance regulator (CFTR) modulator therap…
View article: Trends in Cystic Fibrosis–Related Diabetes Epidemiology Between 2003 and 2018 From the U.S. Cystic Fibrosis Foundation Patient Registry
Trends in Cystic Fibrosis–Related Diabetes Epidemiology Between 2003 and 2018 From the U.S. Cystic Fibrosis Foundation Patient Registry Open
OBJECTIVE A number of disease-modifying therapies have been introduced for people with cystic fibrosis (CF) over the past two decades. The cumulative effects of this changing landscape on cystic fibrosis–related diabetes (CFRD) are unclear…
View article: Trends in Cystic Fibrosis Related Diabetes Epidemiology between 2003-2018 from the US Cystic Fibrosis Foundation Patient Registry
Trends in Cystic Fibrosis Related Diabetes Epidemiology between 2003-2018 from the US Cystic Fibrosis Foundation Patient Registry Open
Objective: A number of disease-modifying therapies have been introduced for people with cystic fibrosis (CF) over the past two decades. The cumulative effects of this changing landscape on Cystic Fibrosis Related Diabetes (CFRD) are…
View article: Trends in Cystic Fibrosis Related Diabetes Epidemiology between 2003-2018 from the US Cystic Fibrosis Foundation Patient Registry
Trends in Cystic Fibrosis Related Diabetes Epidemiology between 2003-2018 from the US Cystic Fibrosis Foundation Patient Registry Open
Objective: A number of disease-modifying therapies have been introduced for people with cystic fibrosis (CF) over the past two decades. The cumulative effects of this changing landscape on Cystic Fibrosis Related Diabetes (CFRD) are…
View article: SHIFTing goals in cystic fibrosis—managing extrapulmonary disease in the era of CFTR modulator therapy; Proceedings of the International Shaping Initiatives and Future Trends (SHIFT) Symposium
SHIFTing goals in cystic fibrosis—managing extrapulmonary disease in the era of CFTR modulator therapy; Proceedings of the International Shaping Initiatives and Future Trends (SHIFT) Symposium Open
Background Cystic fibrosis (CF) is a life‐shortening multisystem genetic disease. Although progressive pulmonary disease is the predominant cause of morbidity and mortality, improvements in treatment for CF‐related lung disease, with assoc…
View article: 581 Glycemia and insulin secretion before and 2 years after elexacaftor-tezacaftor-ivacaftor initiation
581 Glycemia and insulin secretion before and 2 years after elexacaftor-tezacaftor-ivacaftor initiation Open
View article: Effect of Early Glycemic Control in Youth-Onset Type 2 Diabetes on Longer-Term Glycemic Control and β-Cell Function: Results from the TODAY Study
Effect of Early Glycemic Control in Youth-Onset Type 2 Diabetes on Longer-Term Glycemic Control and β-Cell Function: Results from the TODAY Study Open
Objective: Little is known about the impact of early attainment of tight glycemic control on long-term β-cell function and glycemic control in youth-onset type 2 diabetes. We examined the effect of the initial 6 months o…
View article: Effect of Early Glycemic Control in Youth-Onset Type 2 Diabetes on Longer-Term Glycemic Control and β-Cell Function: Results From the TODAY Study
Effect of Early Glycemic Control in Youth-Onset Type 2 Diabetes on Longer-Term Glycemic Control and β-Cell Function: Results From the TODAY Study Open
OBJECTIVE Little is known about the impact of early attainment of tight glycemic control on long-term β-cell function and glycemic control in youth-onset type 2 diabetes. We examined the effect of the initial 6 months of glycemic control o…
View article: Effect of Early Glycemic Control in Youth-Onset Type 2 Diabetes on Longer-Term Glycemic Control and β-Cell Function: Results from the TODAY Study
Effect of Early Glycemic Control in Youth-Onset Type 2 Diabetes on Longer-Term Glycemic Control and β-Cell Function: Results from the TODAY Study Open
Objective: Little is known about the impact of early attainment of tight glycemic control on long-term β-cell function and glycemic control in youth-onset type 2 diabetes. We examined the effect of the initial 6 months o…
View article: Hypoglycemia in children and young adults with cystic fibrosis during oral glucose tolerance testing vs. continuous glucose monitoring
Hypoglycemia in children and young adults with cystic fibrosis during oral glucose tolerance testing vs. continuous glucose monitoring Open
Background Hypoglycemia is common in people with cystic fibrosis (pwCF) during oral glucose tolerance tests (OGTTs) and in the free‐living setting, yet its pathophysiology remains unclear. Objective To evaluate hypoglycemia in children and…
View article: A provider survey of cystic fibrosis related diabetes screening and management practices at North American CF centers
A provider survey of cystic fibrosis related diabetes screening and management practices at North American CF centers Open
Background Cystic Fibrosis Foundation (CFF) Guidelines recommend annual screening for cystic fibrosis related diabetes (CFRD) with an oral glucose tolerance test (OGTT). However, screening rates remain consistently low. We conducted survey…
View article: Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes
Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes Open
Cystic fibrosis (CF) is a recessive disorder arising from mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is expressed in numerous tissues, with high expression in the airways, sm…
View article: Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes
Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes Open
Cystic fibrosis (CF) is a recessive disorder arising from mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is expressed in numerous tissues, with high expression in the airways, sm…
View article: Predictive Value of 1-Hour Glucose Elevations during Oral Glucose Tolerance Testing for Cystic Fibrosis-Related Diabetes
Predictive Value of 1-Hour Glucose Elevations during Oral Glucose Tolerance Testing for Cystic Fibrosis-Related Diabetes Open
Background. In cystic fibrosis-related diabetes (CFRD) screening, oral glucose tolerance test (OGTT) thresholds for detecting prediabetes and diabetes are defined by the 2-hour glucose (2 hG). Intermediate OGTT glucoses, between 0 and 2 ho…
View article: Unique plasma metabolite signature for adolescents with Klinefelter syndrome reveals altered fatty acid metabolism
Unique plasma metabolite signature for adolescents with Klinefelter syndrome reveals altered fatty acid metabolism Open
Conditions related to cardiometabolic disease, including metabolic syndrome and type 2 diabetes, are common among men with Klinefelter syndrome (KS). The molecular mechanisms underlying this aberrant metabolism in KS are largely unknown, a…
View article: Spatiotemporal Assessment of PM2.5 Exposure of a High-risk Occupational Group in a Southeast Asian Megacity
Spatiotemporal Assessment of PM2.5 Exposure of a High-risk Occupational Group in a Southeast Asian Megacity Open
Drivers of open-air public utility jeepneys (PUJs) in the Philippines are regularly exposed to severe levels of fine particulate pollution (PM2.5), making them the appropriate sub-population for investigating the health impacts of PM2.5 on…
View article: <scp>ISPAD</scp> Clinical Practice Consensus Guidelines 2022: Management of cystic fibrosis‐related diabetes in children and adolescents
<span>ISPAD</span> Clinical Practice Consensus Guidelines 2022: Management of cystic fibrosis‐related diabetes in children and adolescents Open
View article: Glycemia and β-cell function before and after elexacaftor/tezacaftor/ivacaftor in youth and adults with cystic fibrosis
Glycemia and β-cell function before and after elexacaftor/tezacaftor/ivacaftor in youth and adults with cystic fibrosis Open
View article: Inferring Insulin Secretion Rate from Sparse Patient Glucose and Insulin Measures
Inferring Insulin Secretion Rate from Sparse Patient Glucose and Insulin Measures Open
The insulin secretion rate (ISR) contains information that can provide a personal, quantitative understanding of endocrine function. If the ISR can be reliably inferred from measurements, it could be used for understanding and clinically d…
View article: Inferring Insulin Secretion Rate From Sparse Patient Glucose and Insulin Measures
Inferring Insulin Secretion Rate From Sparse Patient Glucose and Insulin Measures Open
The insulin secretion rate (ISR) contains information that can provide a personal, quantitative understanding of endocrine function. The ISR, if it can be reliably inferred from sparse measurements, could be used both for understanding the…
View article: 11-Oxyandrogens in Adolescents With Polycystic Ovary Syndrome
11-Oxyandrogens in Adolescents With Polycystic Ovary Syndrome Open
Context Polycystic ovary syndrome (PCOS) is common and diagnosis requires an elevated testosterone. The clinical importance of adrenal 11-oxyandrogens in PCOS is unclear. Objective We sought to determine if 11-oxyandrogens 1) better identi…
View article: Cystic fibrosis-related diabetes: Prevalence, screening, and diagnosis
Cystic fibrosis-related diabetes: Prevalence, screening, and diagnosis Open
Cystic fibrosis-related diabetes (CFRD) is the most common comorbidity in patients with cystic fibrosis (CF). Prevalence of CFRD increases with age and is greater with severe mutations. Other risk factors associated with CFRD are female se…
View article: Impaired glucose tolerance and indeterminate glycemia in cystic fibrosis
Impaired glucose tolerance and indeterminate glycemia in cystic fibrosis Open
View article: Risk Factors for Diabetic Peripheral Neuropathy in Adolescents and Young Adults With Type 2 Diabetes: Results From the TODAY Study
Risk Factors for Diabetic Peripheral Neuropathy in Adolescents and Young Adults With Type 2 Diabetes: Results From the TODAY Study Open
Objective: Data related to diabetic neuropathy in youth with type 2 diabetes are limited. We examined the relationship of glycemic control, sex, race-ethnicity, BMI, and other type 2 diabetes-associated factors with the development …
View article: Risk Factors for Diabetic Peripheral Neuropathy in Adolescents and Young Adults With Type 2 Diabetes: Results From the TODAY Study
Risk Factors for Diabetic Peripheral Neuropathy in Adolescents and Young Adults With Type 2 Diabetes: Results From the TODAY Study Open
Objective: Data related to diabetic neuropathy in youth with type 2 diabetes are limited. We examined the relationship of glycemic control, sex, race-ethnicity, BMI, and other type 2 diabetes-associated factors with the development …
View article: Risk Factors for Diabetic Peripheral Neuropathy in Adolescents and Young Adults With Type 2 Diabetes: Results From the TODAY Study
Risk Factors for Diabetic Peripheral Neuropathy in Adolescents and Young Adults With Type 2 Diabetes: Results From the TODAY Study Open
OBJECTIVE Data related to diabetic neuropathy in youth with type 2 diabetes are limited. We examined the relationship of glycemic control, sex, race/ethnicity, BMI, and other type 2 diabetes-associated factors with the development of diabe…
View article: 18: Effect of clinical initiation of elexacaftor/tezacaftor/ivacaftor on glucose homeostasis in patients with cystic fibrosis
18: Effect of clinical initiation of elexacaftor/tezacaftor/ivacaftor on glucose homeostasis in patients with cystic fibrosis Open