Christine M. Roberts
YOU?
Author Swipe
View article: Stepping Up Psychosis: The Use of Virtual Reality in Pre-registration Mental Health Nursing Education
Stepping Up Psychosis: The Use of Virtual Reality in Pre-registration Mental Health Nursing Education Open
Background: There has been growing interest in the development of mental health-related simulation packages for pre-registration mental health nursing education. The authors will present the creation of a simulation package created for pre…
View article: Classifying the non-metabolic demands of different physical activity types: The Physical Activity Demand (PAD) typology
Classifying the non-metabolic demands of different physical activity types: The Physical Activity Demand (PAD) typology Open
Different physical activity types vary in metabolic demand (intensity), but also in non-metabolic physical demand (balance, co-ordination, speed and flexibility), cognitive demand (attention, memory and decision making), and social demand …
View article: Typology of Physical Activity v1
Typology of Physical Activity v1 Open
Different physical activity types vary in metabolic demand (intensity), but also in non-metabolic demand (balance, co-ordination, speed and flexibility), cognitive demand (attention, memory and decision making), and social demand (social i…
View article: Amyloid beta acts synergistically as a pro-inflammatory cytokine
Amyloid beta acts synergistically as a pro-inflammatory cytokine Open
The amyloid beta (Aβ) peptide is believed to play a central role in Alzheimer's disease (AD), the most common age-related neurodegenerative disorder. However, the natural, evolutionarily selected functions of Aβ are incompletely understood…
View article: Amyloid beta acts synergistically as a pro-inflammatory cytokine
Amyloid beta acts synergistically as a pro-inflammatory cytokine Open
SUMMARY The amyloid beta (Aβ) peptide is believed to play a central role in Alzheimer’s disease (AD), the most common age-related neurodegenerative disorder. However, the natural, evolutionarily-selected functions of Aβ are incompletely un…
View article: The <i>Caenorhabditis elegans</i> Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2
The <i>Caenorhabditis elegans</i> Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2 Open
TDP-1 is the Caenorhabditis elegans ortholog of mammalian TDP-43, which is strongly implicated in the etiology of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). We discovered that deletion of the tdp-1 gene results …
View article: Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21
Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21 Open
Trisomy of chromosome 21, the genetic cause of Down syndrome, has the potential to alter expression of genes on chromosome 21, as well as other locations throughout the genome. These transcriptome changes are likely to underlie the Down sy…
View article: Additional file 2: of In vivo induction of membrane damage by β-amyloid peptide oligomers
Additional file 2: of In vivo induction of membrane damage by β-amyloid peptide oligomers Open
Individual Experiment Data. (XLSX 21 kb)
View article: Sedimentation Velocity Analysis with Fluorescence Detection of Mutant Huntingtin Exon 1 Aggregation in <i>Drosophila melanogaster</i> and <i>Caenorhabditis elegans</i>
Sedimentation Velocity Analysis with Fluorescence Detection of Mutant Huntingtin Exon 1 Aggregation in <i>Drosophila melanogaster</i> and <i>Caenorhabditis elegans</i> Open
At least nine neurodegenerative diseases that are caused by the aggregation induced by long tracts of glutamine sequences have been identified. One such polyglutamine-containing protein is huntingtin, which is the primary factor responsibl…
View article: Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21
Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21 Open
Trisomy of chromosome 21, the genetic cause of Down syndrome, has the potential to alter expression of genes on chromosome 21, as well as other locations throughout the genome. These transcriptome changes are likely to underlie the Down sy…