Christine Passerieux
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View article: First implementation of a collaborative care model for common mental disorders in primary care in France: Fidelity of care manager intervention matters
First implementation of a collaborative care model for common mental disorders in primary care in France: Fidelity of care manager intervention matters Open
Background Care for common mental disorders relies on primary care, where they often remain undiagnosed and untreated. The collaborative care model (CoCM) is a team-based approach involving care managers (CMs) who work alongside general pr…
View article: Effectiveness of a Web-Based Virtual Simulation to Train Nursing Students in Suicide Risk Assessment: Randomized Controlled Investigation
Effectiveness of a Web-Based Virtual Simulation to Train Nursing Students in Suicide Risk Assessment: Randomized Controlled Investigation Open
Background Suicide is a leading cause of preventable death worldwide. Nurses play a critical role in suicide prevention; yet, they face significant obstacles. Improving the evaluation and management of patients at risk of suicide requires …
View article: Discrete early maladaptive schema subgroups in remitted bipolar disorders: association with neuropsychological performance, residual symptoms, and psychosocial functioning
Discrete early maladaptive schema subgroups in remitted bipolar disorders: association with neuropsychological performance, residual symptoms, and psychosocial functioning Open
Objectives To better understand the disability and heterogeneity in terms of residual symptoms and psychosocial and cognitive functioning in bipolar disorders (BD), individual discrepancies in the activation of early maladaptive schemas (E…
View article: Effectiveness of a virtual simulation to train nursing students in suicide risk assessment: a randomized-controlled investigation (Preprint)
Effectiveness of a virtual simulation to train nursing students in suicide risk assessment: a randomized-controlled investigation (Preprint) Open
BACKGROUND Suicide is a leading cause of preventable death worldwide. Nurses play a critical role in suicide prevention, yet face significant obstacles. Improving the evaluation and management of patients at risk of suicide requires innov…
View article: Comparative analysis of anticholinergic burden scales to explain iatrogenic cognitive impairment in schizophrenia: results from the multicenter FACE-SZ cohort
Comparative analysis of anticholinergic burden scales to explain iatrogenic cognitive impairment in schizophrenia: results from the multicenter FACE-SZ cohort Open
Aim The anticholinergic properties of medications are associated with poorer cognitive performance in schizophrenia. Numerous scales have been developed to assess anticholinergic burden and yet, there is no consensus indicating which antic…
View article: Relationships between cognition, functioning, and quality of life of euthymic patients with bipolar disorder: Structural equation modeling with the FACE-BD cohort
Relationships between cognition, functioning, and quality of life of euthymic patients with bipolar disorder: Structural equation modeling with the FACE-BD cohort Open
Background Quality of life is decreased in bipolar disorders (BD) and contributes to poor prognosis. However, little is known about the causal pathways that may affect it. This study aimed to explore health-related QoL (HRQoL) in BD and in…
View article: Predictors of medication adherence in a large 1-year prospective cohort of individuals with schizophrenia: insights from the multicentric FACE-SZ dataset
Predictors of medication adherence in a large 1-year prospective cohort of individuals with schizophrenia: insights from the multicentric FACE-SZ dataset Open
Schizophrenia is characterized by the most salient medication adherence problems among severe mental disorders, but limited prospective data are available to predict and improve adherence in this population. This investigation aims to iden…
View article: Predictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative
Predictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative Open
The bipolar clinical research community is poised to work together to characterize the multi-dimensional contributors to impairment and address the barriers that impede patients' complete recovery. We must also identify the core features w…
View article: Comparative analysis of anticholinergic burden scales to explain iatrogenic cognitive impairment and self-reported side effects in the euthymic phase of bipolar disorders: Results from the FACE-BD cohort
Comparative analysis of anticholinergic burden scales to explain iatrogenic cognitive impairment and self-reported side effects in the euthymic phase of bipolar disorders: Results from the FACE-BD cohort Open
View article: Comparative analysis of anticholinergic burden scales to explain iatrogenic cognitive impairment and self-reported side effects in the euthymic phase of bipolar disorders: results from the FACE-BD cohort
Comparative analysis of anticholinergic burden scales to explain iatrogenic cognitive impairment and self-reported side effects in the euthymic phase of bipolar disorders: results from the FACE-BD cohort Open
Bipolar disorders (BD) are characterized by cognitive impairment during the euthymic phase, to which treatments can contribute. The anticholinergic properties of medications, i.e., the ability of a treatment to inhibit cholinergic receptor…
View article: Relationships between neuropsychological performance, insight, medication adherence, and social metacognition in schizophrenia
Relationships between neuropsychological performance, insight, medication adherence, and social metacognition in schizophrenia Open
View article: Immuno-metabolic profile of patients with psychotic disorders and metabolic syndrome. Results from the FACE-SZ cohort
Immuno-metabolic profile of patients with psychotic disorders and metabolic syndrome. Results from the FACE-SZ cohort Open
We have identified five cytokines associated with MetS in SZ suggesting that patients with psychotic disorders and MetS are characterized by a specific "immuno-metabolic" profile. This may help to design tailored treatments for this subgro…
View article: Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative
Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative Open
Objectives Persistent functional impairment is common in bipolar disorder (BD) and is influenced by a number of demographic, clinical, and cognitive features. The goal of this project was to estimate and compare the influence of key factor…
View article: Direct medical cost of bipolar disorder: Insights from the FACE-BD longitudinal cohort
Direct medical cost of bipolar disorder: Insights from the FACE-BD longitudinal cohort Open
View article: Handedness as a neurodevelopmental marker in schizophrenia: Results from the FACE-SZ cohort
Handedness as a neurodevelopmental marker in schizophrenia: Results from the FACE-SZ cohort Open
Non-right and mixed-handedness are very high in patients with SZ, possibly reflecting a neurodevelopmental origin. NRH is associated with learning disorders and cannabis use. Mixed-handedness is associated with positive symptoms, current d…
View article: Violent suicide attempt history in elderly patients with bipolar disorder: The role of sex, abdominal obesity, and verbal memory: Results from the FACE-BD cohort (FondaMental Advanced center of Expertise for Bipolar Disorders)
Violent suicide attempt history in elderly patients with bipolar disorder: The role of sex, abdominal obesity, and verbal memory: Results from the FACE-BD cohort (FondaMental Advanced center of Expertise for Bipolar Disorders) Open
View article: Exploring Clinical Correlates of Metacognition in Bipolar Disorders Using Moderation Analyses: The Role of Antipsychotics
Exploring Clinical Correlates of Metacognition in Bipolar Disorders Using Moderation Analyses: The Role of Antipsychotics Open
The determinants of metacognition are still poorly understood in bipolar disorders (BD). We aimed to examine the clinical determinants of metacognition, defined as the agreement between objective and subjective cognition in individuals wit…
View article: Evaluating the effectiveness of a single-day simulation-based program in psychiatry for medical students: a controlled study
Evaluating the effectiveness of a single-day simulation-based program in psychiatry for medical students: a controlled study Open
View article: Redefining peripheral inflammation signature in schizophrenia based on the real-world FACE-SZ cohort
Redefining peripheral inflammation signature in schizophrenia based on the real-world FACE-SZ cohort Open
View article: Immune signatures of treatment resistant schizophrenia: a FACE-SZ study
Immune signatures of treatment resistant schizophrenia: a FACE-SZ study Open
International audience
View article: Collectif « Didactique pour enseigner ». (2020). Enseigner, ça s’apprend
Collectif « Didactique pour enseigner ». (2020). Enseigner, ça s’apprend Open
La collection « Mythes et réalités » aux éditions Retz s’enrichit d’un nouveau titre. Comme les précédents, il déconstruit nombre de conceptions devenues parfois des idées reçues, qui traversent les débats sur l’éducation et souvent s’enli…
View article: Immune Signatures of Treatment-Resistant Schizophrenia: A FondaMental Academic Centers of Expertise for Schizophrenia (FACE-SZ) Study
Immune Signatures of Treatment-Resistant Schizophrenia: A FondaMental Academic Centers of Expertise for Schizophrenia (FACE-SZ) Study Open
Treatment-resistant schizophrenia (TRS) affects around 30% of patients with schizophrenia (SZ) resulting in poor functioning, relapses, and reduced quality of life. Convergent findings show that inflammation could contribute to resistance.…
View article: Confidence in visual motion discrimination is preserved in individuals with schizophrenia
Confidence in visual motion discrimination is preserved in individuals with schizophrenia Open
Background Metacognition is the set of reflexive processes that allows humans to evaluate the accuracy of their mental operations. Metacognitive deficits have been described in people with schizophrenia using mostly narrative assessment, a…
View article: Effectiveness of a One-day Simulation-based Program in Psychiatry for Medical Students: A Controlled Study
Effectiveness of a One-day Simulation-based Program in Psychiatry for Medical Students: A Controlled Study Open
Background : Training in psychiatry requires specific knowledge, attitudes, and skills that are obtainable by simulation, which needs further development for medical students. After an analysis of previous research with medical students, w…
View article: Clinical predictors of recurrences in bipolar disorders type 1 and 2: A FACE-BD longitudinal study
Clinical predictors of recurrences in bipolar disorders type 1 and 2: A FACE-BD longitudinal study Open
View article: Author response for "Non‐Alcoholic Fatty Liver Disease in a sample of individuals with Bipolar Disorders: Results From the FACE‐BD Cohort"
Author response for "Non‐Alcoholic Fatty Liver Disease in a sample of individuals with Bipolar Disorders: Results From the FACE‐BD Cohort" Open
View article: Determinants of the remission heterogeneity in bipolar disorders: The importance of early maladaptive schemas (EMS)
Determinants of the remission heterogeneity in bipolar disorders: The importance of early maladaptive schemas (EMS) Open
View article: Evolution and characteristics of the use of valproate in women of childbearing age with bipolar disorder: Results from the FACE-BD cohort
Evolution and characteristics of the use of valproate in women of childbearing age with bipolar disorder: Results from the FACE-BD cohort Open
View article: Metabolic and psychiatric effects of acyl coenzyme A binding protein (ACBP)/diazepam binding inhibitor (DBI)
Metabolic and psychiatric effects of acyl coenzyme A binding protein (ACBP)/diazepam binding inhibitor (DBI) Open
Acyl coenzyme A binding protein (ACBP), also known as diazepam binding inhibitor (DBI) is a multifunctional protein with an intracellular action (as ACBP), as well as with an extracellular role (as DBI). The plasma levels of soluble ACBP/D…
View article: Contribution of common and rare damaging variants in familial forms of bipolar disorder and phenotypic outcome
Contribution of common and rare damaging variants in familial forms of bipolar disorder and phenotypic outcome Open
Genome-wide association studies on bipolar disorders (BD) have revealed an additive polygenic contribution of common single-nucleotide polymorphisms (SNPs). However, these SNPs explain only 25% of the overall genetic variance and suggest a…