Christine Ulz
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View article: Clinical Application of ISO and CEN/TS Standards for Liquid Biopsies—Information Everybody Wants but Nobody Wants to Pay For
Clinical Application of ISO and CEN/TS Standards for Liquid Biopsies—Information Everybody Wants but Nobody Wants to Pay For Open
Background Liquid biopsies are emerging as valuable clinical biomarkers for cancer monitoring. Although International Organization for Standards (ISO) and Technical Specifications from the European Committee for Standardization (CEN/TS) st…
View article: Circulating tumor cell characterization and classification by novel combinatorial dual-color (CoDuCo) in situ hybridization and supervised machine learning
Circulating tumor cell characterization and classification by novel combinatorial dual-color (CoDuCo) in situ hybridization and supervised machine learning Open
Metastatic prostate cancer is a highly heterogeneous and dynamic disease and practicable tools for patient stratification and resistance monitoring are urgently needed. Liquid biopsy analysis of circulating tumor DNA and circulating tumor …
View article: Clinical application of ISO and CEN/TS standards for liquid biopsies - information everybody wants but nobody wants to pay for
Clinical application of ISO and CEN/TS standards for liquid biopsies - information everybody wants but nobody wants to pay for Open
Background Liquid biopsies are emerging as valuable clinical biomarkers for cancer monitoring. Despite increasing clinical use, standardization remains a challenge. ISO and CEN/TS standardized workflows exist, but their integration into cl…
View article: Non‐invasive molecular profiling of skin lesions using tape‐stripping
Non‐invasive molecular profiling of skin lesions using tape‐stripping Open
The incidence of malignant melanoma (MM) is continuously rising with nearly 300.000 cases worldwide in 2018, mostly due to improved early detection.1, 2 Dermoscopy showed an excellent diagnostic accuracy to distinguish early melanoma from …
View article: Residual Humidity in Paraffin-Embedded Tissue Reduces Nucleic Acid Stability
Residual Humidity in Paraffin-Embedded Tissue Reduces Nucleic Acid Stability Open
Molecular diagnostics in healthcare relies increasingly on genomic and transcriptomic methodologies and requires appropriate tissue specimens from which nucleic acids (NA) of sufficiently high quality can be obtained. Besides the duration …
View article: Residual Humidity in Paraffin Embedded Tissue Reduces Nucleic Acid Stability
Residual Humidity in Paraffin Embedded Tissue Reduces Nucleic Acid Stability Open
Molecular diagnostics in healthcare relies increasingly on genomic and transcriptomic method-ologies and requires appropriate tissue specimens from which nucleic acids (NA) of sufficiently high quality can be obtained. Besides suration of …
View article: Technical Evaluation of Commercial Mutation Analysis Platforms and Reference Materials for Liquid Biopsy Profiling
Technical Evaluation of Commercial Mutation Analysis Platforms and Reference Materials for Liquid Biopsy Profiling Open
Molecular profiling from liquid biopsy, in particular cell-free DNA (cfDNA), represents an attractive alternative to tissue biopsies for the detection of actionable targets and tumor monitoring. In addition to PCR-based assays, Next Genera…