Christofer Bester
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View article: Electrocochleography for Monitoring Hearing Preservation During Cochlear Implantation
Electrocochleography for Monitoring Hearing Preservation During Cochlear Implantation Open
Importance Many cochlear implant candidates retain residual hearing, which can improve speech perception and overall outcomes. However, residual hearing is frequently lost during implantation. Intraoperative electrocochleography may enable…
View article: The effect of surgical complexity on hearing preservation during cochlear implantation with sheathed perimodiolar electrodes
The effect of surgical complexity on hearing preservation during cochlear implantation with sheathed perimodiolar electrodes Open
Purpose The causes of residual hearing loss during cochlear implantation are generally poorly understood. This study sought to understand whether the complexity of this surgical approach related to a loss of residual hearing. Method Thirty…
View article: Amplitude and Phase Changes in Electrocochleographic Real-Time Recordings During Cochlear Implantation and Its Relation to Pre- and Postoperative Hearing
Amplitude and Phase Changes in Electrocochleographic Real-Time Recordings During Cochlear Implantation and Its Relation to Pre- and Postoperative Hearing Open
Background The aim of this study was to relate response patterns of electrocochleography (ECochG) recordings during cochlear implantation to pre- and postoperative hearing. Methods Thirty subjects with either flat (FA, n = 9) or sloping (S…
View article: Improving Real-Time Feedback During Cochlear Implantation: The Auditory Nerve Neurophonic/Cochlear Microphonic Ratio
Improving Real-Time Feedback During Cochlear Implantation: The Auditory Nerve Neurophonic/Cochlear Microphonic Ratio Open
Objectives: Real-time monitoring of cochlear function to predict the loss of residual hearing after cochlear implantation is now possible. Current approaches monitor the cochlear microphonic (CM) during implantation from the electrode at t…
View article: Robust online drop detection for cochlear implant surgery
Robust online drop detection for cochlear implant surgery Open
Hearing loss is an impairment that affects a large population worldwide. Cochlear implant (CI) surgery is an effective solution, especially in patients with residual, natural hearing. However, the risk of intracochlear damage during CI sur…
View article: Robust Online Trauma Detection for Cochlear Implant Surgery
Robust Online Trauma Detection for Cochlear Implant Surgery Open
Hearing loss is an impairment that affects a large population worldwide. Cochlear Implantation (CI) is an effective solution, especially in patients with residual, natural hearing. However, the risk of intracochlear damage during CI surger…
View article: Stochastic Diffusion: A Diffusion Probabilistic Model for Stochastic Time Series Forecasting
Stochastic Diffusion: A Diffusion Probabilistic Model for Stochastic Time Series Forecasting Open
Recent innovations in diffusion probabilistic models have paved the way for significant progress in image, text and audio generation, leading to their applications in generative time series forecasting. However, leveraging such abilities t…
View article: Time Series Representation Learning with Supervised Contrastive Temporal Transformer
Time Series Representation Learning with Supervised Contrastive Temporal Transformer Open
Finding effective representations for time series data is a useful but challenging task. Several works utilize self-supervised or unsupervised learning methods to address this. However, there still remains the open question of how to lever…
View article: Editorial: Biomarkers of peripheral and central auditory system integrity and function
Editorial: Biomarkers of peripheral and central auditory system integrity and function Open
Keywords: auditory system, diagnostic and therapeutic applications, patient-centered approaches, biomarkers, technological advances
View article: Time-Transformer: Integrating Local and Global Features for Better Time Series Generation
Time-Transformer: Integrating Local and Global Features for Better Time Series Generation Open
Generating time series data is a promising approach to address data deficiency problems. However, it is also challenging due to the complex temporal properties of time series data, including local correlations as well as global dependencie…
View article: Intra‐cochlear Flushing Reduces Tissue Response to Cochlear Implantation
Intra‐cochlear Flushing Reduces Tissue Response to Cochlear Implantation Open
Introduction Intraoperative trauma leading to bleeding during cochlear implantation negatively impacts residual hearing of cochlear implant recipients. There are no clinical protocols for the removal of blood during implantation, to reduce…
View article: Speech-in-noise performance in objectively determined cochlear implant maps, including the effect of cognitive state
Speech-in-noise performance in objectively determined cochlear implant maps, including the effect of cognitive state Open
Objective Cochlear Implant (CI) programming based on subjective psychophysical fine-tuning of loudness scaling involves active participation and cognitive skills and thus may not be appropriate for difficult-to-condition populations. The e…
View article: Characteristics of the Summating Potential Measured Across a Cochlear Implant Array as an Indicator of Cochlear Function
Characteristics of the Summating Potential Measured Across a Cochlear Implant Array as an Indicator of Cochlear Function Open
Objectives: The underlying state of cochlear and neural tissue function is known to affect postoperative speech perception following cochlear implantation. The ability to assess these tissues in patients can be performed using intracochlea…
View article: Monitoring Cochlear Health With Intracochlear Electrocochleography During Cochlear Implantation: Findings From an International Clinical Investigation
Monitoring Cochlear Health With Intracochlear Electrocochleography During Cochlear Implantation: Findings From an International Clinical Investigation Open
Objectives: Electrocochleography (ECochG) is emerging as a tool for monitoring cochlear function during cochlear implant (CI) surgery. ECochG may be recorded directly from electrodes on the implant array intraoperatively. For low-frequency…
View article: Automatic analysis of cochlear response using electrocochleography signals during cochlear implant surgery
Automatic analysis of cochlear response using electrocochleography signals during cochlear implant surgery Open
Cochlear implants (CIs) provide an opportunity for the hearing impaired to perceive sound through electrical stimulation of the hearing (cochlear) nerve. However, there is a high risk of losing a patient’s natural hearing during CI surgery…
View article: Spironolactone Ameliorates Cochlear Implant Induced Endolymphatic Hydrops
Spironolactone Ameliorates Cochlear Implant Induced Endolymphatic Hydrops Open
Background Endolymphatic hydrops (EH) has been observed in both animal and human cochleae following cochlear implant (CI) surgery. We tested whether EH could be eliminated by administration of mineralocorticoid steroid antagonist spironola…
View article: Intraoperative Observational Real-time Electrocochleography as a Predictor of Hearing Loss After Cochlear Implantation: 3 and 12 Month Outcomes
Intraoperative Observational Real-time Electrocochleography as a Predictor of Hearing Loss After Cochlear Implantation: 3 and 12 Month Outcomes Open
Objective: A decrease in intracochlear electrocochleographic (ECochG) amplitude during cochlear implantation has been associated with poorer postoperative hearing preservation in several short-term studies. Here, we relate the stability of…
View article: Four-point impedance as a biomarker for bleeding during cochlear implantation
Four-point impedance as a biomarker for bleeding during cochlear implantation Open
Cochlear implantation has successfully restored the perception of hearing for nearly 200 thousand profoundly deaf adults and children. More recently, implant candidature has expanded to include those with considerable natural hearing which…
View article: Nanomechanical mapping reveals localized stiffening of the basilar membrane after cochlear implantation
Nanomechanical mapping reveals localized stiffening of the basilar membrane after cochlear implantation Open
Cochlear implantation leads to many structural changes within the cochlea which can impair residual hearing. In patients with preserved low-frequency hearing, a delayed hearing loss can occur weeks-to-years post-implantation. We explore wh…
View article: Characterizing Electrocochleography in Cochlear Implant Recipients with Residual Low-Frequency Hearing
Characterizing Electrocochleography in Cochlear Implant Recipients with Residual Low-Frequency Hearing Open
Objective: Lay the groundwork for using electrocochleography (ECochG) as a measure of cochlear health, by characterizing typical patterns of the ECochG response observed across the electrode array in cochlear implant recipients with residu…
View article: Supplementary Material for: Electrophysiological Evidence of the Basilar-Membrane Travelling Wave and Frequency Place Coding of Sound in Cochlear Implant Recipients
Supplementary Material for: Electrophysiological Evidence of the Basilar-Membrane Travelling Wave and Frequency Place Coding of Sound in Cochlear Implant Recipients Open
Aim: To obtain direct evidence for the cochlear travelling wave in humans by performing electrocochleography from within the cochlea in subjects implanted with an auditory prosthesis. Background: Sound induces a travelling wave that propag…
View article: Supplementary Material for: Electrophysiological Evidence of the Basilar-Membrane Travelling Wave and Frequency Place Coding of Sound in Cochlear Implant Recipients
Supplementary Material for: Electrophysiological Evidence of the Basilar-Membrane Travelling Wave and Frequency Place Coding of Sound in Cochlear Implant Recipients Open
Aim: To obtain direct evidence for the cochlear travelling wave in humans by performing electrocochleography from within the cochlea in subjects implanted with an auditory prosthesis. Background: Sound induces a travelling wave that propag…
View article: Selective attentional processes in cochlear implant recipients: Measurements of the attentional filter
Selective attentional processes in cochlear implant recipients: Measurements of the attentional filter Open
In normal hearing subjects, detection of near-threshold tones in noise is influenced by signal certainty. Thus, tones that are presented more frequently than others, and/or are preceded by a clearly audible cue tone of the same frequency (…