Christophe Garcie
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View article: Reappraising Cladophialophora bantiana phaeohyphomycosis in France: retrospective nation-based study
Reappraising Cladophialophora bantiana phaeohyphomycosis in France: retrospective nation-based study Open
Santé Publique France.
View article: Cladophialophora Bantiana  Phaeohyphomycosis in France: A Reappraisal of Epidemiology, Therapeutic Strategy, and Outcome
Cladophialophora Bantiana Phaeohyphomycosis in France: A Reappraisal of Epidemiology, Therapeutic Strategy, and Outcome Open
View article: The Polyamine Spermidine Modulates the Production of the Bacterial Genotoxin Colibactin
The Polyamine Spermidine Modulates the Production of the Bacterial Genotoxin Colibactin Open
Colibactin-producing Escherichia coli strains are associated with cancerous and precancerous colorectal tissues and are suspected of promoting colorectal carcinogenesis. In this study, we describe a new interplay between the synthesis of t…
View article: High iron supply inhibits the synthesis of the genotoxin colibactin by pathogenic Escherichia coli through a non-canonical Fur/RyhB-mediated pathway
High iron supply inhibits the synthesis of the genotoxin colibactin by pathogenic Escherichia coli through a non-canonical Fur/RyhB-mediated pathway Open
The genotoxin colibactin is a secondary metabolite produced by a variety of pathogenic Enterobacteria, and is associated with colon cancer development and acute systemic infections. The colibactin biosynthesis requires the enzymatic activi…
View article: Interplay between siderophores and colibactin genotoxin in <i>Escherichia coli</i>
Interplay between siderophores and colibactin genotoxin in <i>Escherichia coli</i> Open
Highly pathogenic Escherichia coli strains that belong to the phylogenetic group B2 have developed a greater ability to acquire iron (heme receptor and numerous siderophores), to produce the genotoxin colibactin and to synthesize antimicro…
View article: Modulation atypique de la biosynthèse de la colibactine, une génotoxine de Escherichia coli, ou comment un îlot génomique est en symbiose avec le chromosome bactérien
Modulation atypique de la biosynthèse de la colibactine, une génotoxine de Escherichia coli, ou comment un îlot génomique est en symbiose avec le chromosome bactérien Open
L'îlot génomique pks code une machinerie de biosynthèse complexe synthétisant la colibactine, une génotoxine produite par certaines souches de Escherichia coli. Cette génotoxine
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View article: Iron Homeostasis Regulates the Genotoxicity of Escherichia coli That Produces Colibactin
Iron Homeostasis Regulates the Genotoxicity of Escherichia coli That Produces Colibactin Open
The genotoxin colibactin is a secondary metabolite produced by a variety of pathogenic enterobacteria. Its biosynthesis requires the enzymatic activity of the phosphopantetheinyl transferase (PPTase) ClbA. We previously showed that ClbA ca…
View article: The Bacterial Stress-Responsive Hsp90 Chaperone (HtpG) Is Required for the Production of the Genotoxin Colibactin and the Siderophore Yersiniabactin in<i>Escherichia coli</i>
The Bacterial Stress-Responsive Hsp90 Chaperone (HtpG) Is Required for the Production of the Genotoxin Colibactin and the Siderophore Yersiniabactin in<i>Escherichia coli</i> Open
The genotoxin colibactin, synthesized by Escherichia coli, is a secondary metabolite belonging to the chemical family of hybrid polyketide/nonribosomal peptide compounds. It is produced by a complex biosynthetic assembly line encoded by th…