Christophe Hano
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View article: Determination of the diastereomeric excesses of chiral flavonoids in organs of Citrus aurantium with two-dimensional supercritical fluid chromatography
Determination of the diastereomeric excesses of chiral flavonoids in organs of Citrus aurantium with two-dimensional supercritical fluid chromatography Open
Citrus aurantium (bitter orange), is widely used in culinary preparations, food supplements, cosmetics and traditional medicine. Its bioactivity is mainly associated to two major glycosylated flavanones, naringin and neohesperidin, each co…
View article: Unveiling the Impact of Oven vs. Microwave Roasting: Enhancing the Physico‐Chemical Properties, Stability, and Bioactive Potential of Prickly Pear Seed Oil
Unveiling the Impact of Oven vs. Microwave Roasting: Enhancing the Physico‐Chemical Properties, Stability, and Bioactive Potential of Prickly Pear Seed Oil Open
This study systematically examines the impacts of conventional oven and microwave roasting at varied temperatures (100, 140, and 180°C) and power levels (400, 600, and 800 W) across different durations (5, 10, 15, 30, and 60 min) on oil yi…
View article: Comparative mechanistic study of green-synthesized silver-zinc oxide (Ag-ZnO) and iron–Zinc oxide (Fe-ZnO) bimetallic nanoparticles in antiglycation, antidiabetic, antioxidant, and anticancer activities
Comparative mechanistic study of green-synthesized silver-zinc oxide (Ag-ZnO) and iron–Zinc oxide (Fe-ZnO) bimetallic nanoparticles in antiglycation, antidiabetic, antioxidant, and anticancer activities Open
Bimetallic nanoparticles (BNPs) have gained immense attention for their diverse biological applications. This study aimed to biosynthesize and characterize Ag-ZnONPs and Fe-ZnONPs and compare their potential as therapeutic agents. The BNPs…
View article: Selenium Nanoparticles in Cancer Therapy: Unveiling Cytotoxic Mechanisms and Therapeutic Potential
Selenium Nanoparticles in Cancer Therapy: Unveiling Cytotoxic Mechanisms and Therapeutic Potential Open
Background Cancer represents a complex group of diseases characterized by abnormal cell proliferation, invasion, and metastasis. These features pose significant challenges to conventional therapeutic approaches, necessitating the developme…
View article: Editorial: Mechanistic and physiological insights into plant nanotechnologies
Editorial: Mechanistic and physiological insights into plant nanotechnologies Open
View article: Relationship Between the Structure of the Flavone C-Glycosides of Linseed (Linum usitatissimum L.) and Their Antioxidant Activity
Relationship Between the Structure of the Flavone C-Glycosides of Linseed (Linum usitatissimum L.) and Their Antioxidant Activity Open
Flavonoids have been documented to have good antioxidant activities in vitro. In recent years, reports on the antioxidant activities of flavone C-glycosides, a subclass of flavonoids, have attracted great attention. Despite the wealth of i…
View article: The cosmetic potential evaluation of the fungus resistant grapevine extracts using metabolomic approaches
The cosmetic potential evaluation of the fungus resistant grapevine extracts using metabolomic approaches Open
Natural product effectiveness is an important criterion to develop new active ingredients for cosmetic industry. Plant metabolites exhibit wide range of natural activities and in recent years, there has been a growing interest in the devel…
View article: Formulation of a Three-Component Essential Oil Mixture from Lavandula dentata, Rosmarinus officinalis, and Myrtus communis for Improved Antioxidant Activity
Formulation of a Three-Component Essential Oil Mixture from Lavandula dentata, Rosmarinus officinalis, and Myrtus communis for Improved Antioxidant Activity Open
The optimization of existing natural antioxidants that are highly effective is crucial for advancements in medicine and the food industry. Due to growing concerns regarding the safety of synthetic antioxidants, researchers are increasingly…
View article: A Comparative Analysis of Morphological Characteristics between Endangered Local Prickly Pear and the Newly Introduced Dactylopius opuntiae-Resistant Species in Eastern Morocco
A Comparative Analysis of Morphological Characteristics between Endangered Local Prickly Pear and the Newly Introduced Dactylopius opuntiae-Resistant Species in Eastern Morocco Open
Prickly pear serves as a significant source of income for farmers worldwide, with production taking place in temperate, subtropical, and cold regions. The objective of the present investigation is to explore the morphological parameters of…
View article: Phenolic Screening and Mixture Design Optimization for <i>In Vitro</i> Assessment of Antioxidant and Antimicrobial Activities of Honey, Propolis, and Bee Pollen
Phenolic Screening and Mixture Design Optimization for <i>In Vitro</i> Assessment of Antioxidant and Antimicrobial Activities of Honey, Propolis, and Bee Pollen Open
The current study used a design of experiments to evaluate the potential synergistic effects of three Moroccan bee products (honey (H), propolis (P), and bee pollen (BP)) on the free radical inhibition and antibacterial activity against cl…
View article: Carob (Ceratonia siliqua L.) Seed Constituents: A Comprehensive Review of Composition, Chemical Profile, and Diverse Applications
Carob (Ceratonia siliqua L.) Seed Constituents: A Comprehensive Review of Composition, Chemical Profile, and Diverse Applications Open
Carob (Ceratonia siliqua L.) is a tree species native to the Mediterranean region and belongs to the Fabaceae family. The tree is well-known for its sweet and nutritious fruits, which have been used for long time as a nutritious food. In a…
View article: Secondary metabolites and their potential roles in plant tolerance against abiotic and biotic stress
Secondary metabolites and their potential roles in plant tolerance against abiotic and biotic stress Open
View article: Sequential selective supercritical fluid extraction (S3FE) of triglycerides and flavonolignans from milk thistle (Silybum marianum L, Gaertn)
Sequential selective supercritical fluid extraction (S3FE) of triglycerides and flavonolignans from milk thistle (Silybum marianum L, Gaertn) Open
Supercritical fluid extraction with carbon dioxide is nowadays one of the best approaches on an economic and ecological point of view for the extraction of natural compounds from plants. Besides, many seeds or fruits contain both lipids, a…
View article: Synthesis of Zinc Oxide Nanoparticles (ZnO NPs) from Leaf Extract of Carthamus oxycantha and its In Vitro Biological Applications
Synthesis of Zinc Oxide Nanoparticles (ZnO NPs) from Leaf Extract of Carthamus oxycantha and its In Vitro Biological Applications Open
Nanotechnology and nanosciences are emerging as new fast-growing fields due to their unique characteristics and phenomenal properties. In this study, we synthesized zinc oxide nanoparticles (ZnO NPs) by using leaf extract of Carthamus oxyc…
View article: Shoot Cultures of Vitis vinifera (Vine Grape) Different Cultivars as a Promising Innovative Cosmetic Raw Material—Phytochemical Profiling, Antioxidant Potential, and Whitening Activity
Shoot Cultures of Vitis vinifera (Vine Grape) Different Cultivars as a Promising Innovative Cosmetic Raw Material—Phytochemical Profiling, Antioxidant Potential, and Whitening Activity Open
The primary purpose of this work was the initiation and optimization of shoot cultures of different Vitis vinifera L. cultivars: cv. Chardonnay, cv. Hibernal, cv. Riesling, cv. Johanniter, cv. Solaris, cv. Cabernet Cortis, and cv. Regent. …
View article: Trans-Resveratrol as a Health Beneficial Molecule: Activity, Sources, and Methods of Analysis
Trans-Resveratrol as a Health Beneficial Molecule: Activity, Sources, and Methods of Analysis Open
Trans-Resveratrol, a natural polyphenol found in various plant species, has gained significant attention due to its potential health-promoting properties. This article reviews the biological activities attributed to trans-Resveratrol, its …
View article: The role of biotechnological tools for mitigating abiotic stress in a changing climate – preface
The role of biotechnological tools for mitigating abiotic stress in a changing climate – preface Open
View article: SNAC3 Transcription Factor Enhances Arsenic Stress Tolerance and Grain Yield in Rice (Oryza sativa L.) through Regulating Physio-Biochemical Mechanisms, Stress-Responsive Genes, and Cryptochrome 1b
SNAC3 Transcription Factor Enhances Arsenic Stress Tolerance and Grain Yield in Rice (Oryza sativa L.) through Regulating Physio-Biochemical Mechanisms, Stress-Responsive Genes, and Cryptochrome 1b Open
Arsenic (As) is one of the toxic heavy metal pollutants found in the environment. An excess of As poses serious threats to plants and diminishes their growth and productivity. NAC transcription factors revealed a pivotal role in enhancing …
View article: The effect of salt stress on the growth and development of three Aloe species in eastern Morocco
The effect of salt stress on the growth and development of three Aloe species in eastern Morocco Open
The salinity stress is an abiotic factor that limits the growth of agricultural crops. Salinity affects over 800 million hectares of worldwide land. Aloe species are xerophytes, perennial plants with succulent leaves that have a crassulace…
View article: Metal-Resistant PGPR Strain Azospirillum brasilense EMCC1454 Enhances Growth and Chromium Stress Tolerance of Chickpea (Cicer arietinum L.) by Modulating Redox Potential, Osmolytes, Antioxidants, and Stress-Related Gene Expression
Metal-Resistant PGPR Strain Azospirillum brasilense EMCC1454 Enhances Growth and Chromium Stress Tolerance of Chickpea (Cicer arietinum L.) by Modulating Redox Potential, Osmolytes, Antioxidants, and Stress-Related Gene Expression Open
Heavy metal stress, including from chromium, has detrimental effects on crop growth and yields worldwide. Plant growth-promoting rhizobacteria (PGPR) have demonstrated great efficiency in mitigating these adverse effects. The present study…
View article: Casticin as potential anticancer agent: recent advancements in multi-mechanistic approaches
Casticin as potential anticancer agent: recent advancements in multi-mechanistic approaches Open
Plants, with their range of pharmacologically active molecules, represent the most promising source for the production of new anticancer drugs and for the formulation of adjuvants in chemotherapy treatments to reduce drug content and/or co…
View article: Chemotherapeutic properties and side-effects associated with the clinical practice of terpene alkaloids: paclitaxel, docetaxel, and cabazitaxel
Chemotherapeutic properties and side-effects associated with the clinical practice of terpene alkaloids: paclitaxel, docetaxel, and cabazitaxel Open
Over the years, many biological and synthetic agents have been explored and tested in attempts to halt the spread of cancer and/or cure it. Currently, several natural compounds have and are being considered in this regard. For example, pac…
View article: Antioxidant Compounds of Potato Breeding Genotypes and Commercial Cultivars with Yellow, Light Yellow, and White Flesh in Iran
Antioxidant Compounds of Potato Breeding Genotypes and Commercial Cultivars with Yellow, Light Yellow, and White Flesh in Iran Open
Potatoes are a staple food with high antioxidant properties that can positively affect population health. The beneficial effects of potatoes have been attributed to tuber quality. However, the tuber quality related researches at genetic le…
View article: Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications
Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications Open
Cancer is still the leading cause of death worldwide, burdening the global medical system. Rosmarinic acid (RA) is among the first secondary metabolites discovered and it is a bioactive compound identified in plants such as Boraginaceae an…
View article: Rapid and Efficient In Vitro Propagation Protocol of Endangered Wild Prickly Pear Growing in Eastern Morocco
Rapid and Efficient In Vitro Propagation Protocol of Endangered Wild Prickly Pear Growing in Eastern Morocco Open
The Opuntia genus is widely recognized as a significant member of the Cactaceae family. The eastern Moroccan prickly pear’s wild ecotype is renowned for its production of fruits of superior quality, which are in high demand. Nonetheless, t…
View article: Antifungal Activity of Juglans-regia-Mediated Silver Nanoparticles (AgNPs) against Aspergillus-ochraceus-Induced Toxicity in In Vitro and In Vivo Settings
Antifungal Activity of Juglans-regia-Mediated Silver Nanoparticles (AgNPs) against Aspergillus-ochraceus-Induced Toxicity in In Vitro and In Vivo Settings Open
Aflatoxins produced by some species of Aspergillus are considered secondary toxic fungal by-products in feeds and food. Over the past few decades, many experts have focused on preventing the production of aflatoxins by Aspergillus ochraceu…
View article: Water Stress and Seed Color Interacting to Impact Seed and Oil Yield, Protein, Mucilage, and Secoisolariciresinol Diglucoside Content in Cultivated Flax (Linum usitatissimum L.)
Water Stress and Seed Color Interacting to Impact Seed and Oil Yield, Protein, Mucilage, and Secoisolariciresinol Diglucoside Content in Cultivated Flax (Linum usitatissimum L.) Open
Flaxseed (Linum usitatissimum L.) is a plant with a wide range of medicinal, health, nutritional, and industrial uses. This study assessed the genetic potential of yellow and brown seeds in thirty F4 families under different water conditio…
View article: Ethnobotanical, Phytochemical, Toxicological, and Pharmacological Properties of Ziziphus lotus (L.) Lam.: A Comprehensive Review
Ethnobotanical, Phytochemical, Toxicological, and Pharmacological Properties of Ziziphus lotus (L.) Lam.: A Comprehensive Review Open
Ziziphus lotus (L.) Lam. (Rhamnaceae) is a plant species found across the Mediterranean area. This comprehensive overview aims to summarize the botanical description and ethnobotanical uses of Z. lotus and its phytochemical compounds deriv…
View article: Thalassemia and Nanotheragnostics: Advanced Approaches for Diagnosis and Treatment
Thalassemia and Nanotheragnostics: Advanced Approaches for Diagnosis and Treatment Open
Thalassemia is a monogenic autosomal recessive disorder caused by mutations, which lead to abnormal or reduced production of hemoglobin. Ineffective erythropoiesis, hemolysis, hepcidin suppression, and iron overload are common manifestatio…
View article: Laboratory-Scale Optimization of Hemp Seed Roasting Temperature and Time for Producing a High-Quality Pressed Oil
Laboratory-Scale Optimization of Hemp Seed Roasting Temperature and Time for Producing a High-Quality Pressed Oil Open
Roasting is widely applied in oil processing to improve the extraction yield and desired sensory characteristics. The current study is aimed at optimizing roasting conditions (time and temperature) of hemp (Cannabis sativa L.) seeds prior …