Christophe Moawad
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View article: Machine Learning-Driven Drug Repurposing for KRAS G12C and KRAS G12D Inhibition
Machine Learning-Driven Drug Repurposing for KRAS G12C and KRAS G12D Inhibition Open
KRAS is a predominant oncogenic driver across multiple cancers, long considered “undruggable” due to its high nucleotide affinity and lack of classical binding pockets. Although recent advances have led to covalent inhibitors like Sotorasi…