Christopher A. Sims
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View article: Population Pharmacokinetic Modeling of Oxcarbazepine and Its Active Metabolite 10-Monohydroxy Derivative to Inform Dosing in Children with Obesity
Population Pharmacokinetic Modeling of Oxcarbazepine and Its Active Metabolite 10-Monohydroxy Derivative to Inform Dosing in Children with Obesity Open
A model-informed analysis confirms that the current pediatric dosing regimen of OXZ applies to children in general, regardless of their obesity status.
View article: Formation of Tesseract Time Crystals on a Quantum Computer
Formation of Tesseract Time Crystals on a Quantum Computer Open
The engineering of new states of matter through Floquet driving has revolutionized the field of condensed matter physics. This technique enables the creation of hybrid topological states and ordered phases that are absent in normal systems…
View article: Variational Quantum PageRank
Variational Quantum PageRank Open
The PageRank algorithm is used to rank web pages by their importance. Since its development, the PageRank algorithm is a critical and fundamental part of search engines today. PageRank is a graph-based algorithm that ranks pages based on h…
View article: Analogous Black Holes in Type-III Dirac Semimetal Ni$_3$In$_2$X$_2$ (X = S, Se)
Analogous Black Holes in Type-III Dirac Semimetal Ni$_3$In$_2$X$_2$ (X = S, Se) Open
Black holes are objects that have a large mass and curve space time, characterized by their event horizon and singularity. Recently, an interesting concept of analogous black holes has emerged in the field of condensed matter physics. In t…
View article: The Fractional Orbital Chern Hall Effect
The Fractional Orbital Chern Hall Effect Open
The fractional quantum hall effect (FQHE) is a milestone of modern day physics, its disovery paved the way for the study of fractional charges which do not obey abelian physics. However, all FQHE require an external magnetic field in order…
View article: Simulation of Higher Dimensional Discrete Time Crystals on a Quantum Computer
Simulation of Higher Dimensional Discrete Time Crystals on a Quantum Computer Open
The study of topologically ordered states have given rise to a growing interest in symmetry protected states in quantum matter. Recently, this theory has been extended to quantum many body systems which demonstrate ordered states at low te…
View article: Highly Accurate FMRI ADHD Classification using time distributed multi modal 3D CNNs
Highly Accurate FMRI ADHD Classification using time distributed multi modal 3D CNNs Open
This work proposes an algorithm for fMRI data analysis for the classification of ADHD disorders. There have been several breakthroughs in the analysis of fMRI via 3D convolutional neural networks (CNNs). With these new techniques it is pos…
View article: Existence of Chern Gaps in Kagome Magnets RMn$_6$Ge$_6$ (R = Nd, Sm, Tb, Dy, Ho, Er, Yb, Lu)
Existence of Chern Gaps in Kagome Magnets RMn$_6$Ge$_6$ (R = Nd, Sm, Tb, Dy, Ho, Er, Yb, Lu) Open
Kagome Chern Magnets are lattices which host a Chern state when they are non-magnetic and a Chern Gap when they become magnetic. These Chern gaps can host fractional Chern Fermions. There has been extensive research in the RMn$_6$Sn$_6$ sy…
View article: SpectroLab: An Open Source Matlab Based Toolbox for High Throughput Spectroscopy Analysis
SpectroLab: An Open Source Matlab Based Toolbox for High Throughput Spectroscopy Analysis Open
We present an open source software package SpectroLab a Matlab-based tool developed in 2018 for the analysis of spectroscopic data. In this package, there are tools for derivative analysis, stacked energy contours, stacked plots for theory…
View article: Edge Detection and Image Filter algorithms for Spectroscopic Analysis with Deep Learning Applications
Edge Detection and Image Filter algorithms for Spectroscopic Analysis with Deep Learning Applications Open
Edge detection and image filters are commonly used in computer vision. However, they have never been applied to the data analysis of angle-resolved photoemission spectroscopy (ARPES) data before in a systematic fashion. In this paper we wi…
View article: Feedbacks: Financial Markets and Economic Activity
Feedbacks: Financial Markets and Economic Activity Open
Is credit expansion a sign of desirable financial deepening or the prelude to an inevitable bust? We study this question in modern US data using a structural VAR model of 10 monthly frequency variables, identified by heteroskedasticity. Ne…
View article: Microcup Arrays for the Efficient Isolation and Cloning of Cells
Microcup Arrays for the Efficient Isolation and Cloning of Cells Open
Arrays of transparent, releasable micron-scale structures termed “microcups” were created for the purpose of patterning and isolating viable cells from small cell samples. Cells were captured by the microcups without the need for barriers …
View article: Optimization of 3-D organotypic primary colonic cultures for organ-on-chip applications
Optimization of 3-D organotypic primary colonic cultures for organ-on-chip applications Open
Background New advances enable long-term organotypic culture of colonic epithelial stem cells that develop into structures known as colonoids. Colonoids represent a primary tissue source acting as a potential starting material for developm…