Christopher Batters
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View article: Plasmodium falciparum Myosin F with a Rab-like tail domain localises to perinuclear membranes and associates with trafficking proteins
Plasmodium falciparum Myosin F with a Rab-like tail domain localises to perinuclear membranes and associates with trafficking proteins Open
Members of the myosin superfamily are found in all eukaryotes, including Plasmodium falciparum , the parasite that causes malaria. Plasmodium falciparum expresses six myosins, but apart from PfMyoA, these motors remain largely uncharacteri…
View article: Structure of a transcribing Pol II-DSIF-SPT6-U1 snRNP complex
Structure of a transcribing Pol II-DSIF-SPT6-U1 snRNP complex Open
In eukaryotic cells, splicing occurs predominantly co-transcriptionally, enhancing splicing efficiency and fidelity while introducing an additional layer of regulation over gene expression. RNA polymerase II (Pol II) facilitates co-transcr…
View article: Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor
Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor Open
Wnt signal transduction relies on the direct inhibition of GSK3 by phosphorylated PPPSPxS motifs within the cytoplasmic tail of the LRP6 co-receptor. How GSK3 is recruited to LRP6 remains unclear. Here, we use nuclear magnetic resonance sp…
View article: The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei
The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei Open
The actin cytoskeleton is a ubiquitous feature of eukaryotic cells, yet its complexity varies across different taxa. In the parasitic protist Trypanosoma brucei , a rudimentary actomyosin system consisting of one actin gene and two myosin …
View article: Author response: The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei
Author response: The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei Open
View article: The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei
The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei Open
The actin cytoskeleton is a ubiquitous feature of eukaryotic cells, yet its complexity varies across different taxa. In the parasitic protist Trypanosoma brucei, a rudimentary actomyosin system consisting of one actin gene and two myosin g…
View article: Author response: The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei
Author response: The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei Open
The actin cytoskeleton is a ubiquitous feature of eukaryotic cells, yet its complexity varies across different taxa. In the parasitic protist Trypanosoma brucei, a rudimentary actomyosin system consisting of one actin gene and two myosin g…
View article: Motor domain phosphorylation increases nucleotide exchange and turns MYO6 into a faster and stronger motor
Motor domain phosphorylation increases nucleotide exchange and turns MYO6 into a faster and stronger motor Open
View article: Membraneless channels sieve cations in ammonia-oxidizing marine archaea
Membraneless channels sieve cations in ammonia-oxidizing marine archaea Open
Nitrosopumilus maritimus is an ammonia-oxidizing archaeon that is crucial to the global nitrogen cycle 1,2 . A critical step for nitrogen oxidation is the entrapment of ammonium ions from a dilute marine environment at the cell surface and…
View article: The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei
The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei Open
The actin cytoskeleton is a ubiquitous feature of eukaryotic cells, yet its complexity varies across different taxa. In the parasitic protist Trypanosoma brucei, a rudimentary actomyosin system consisting of one actin gene and two myosin g…
View article: Reviewer #2 (Public Review): The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei
Reviewer #2 (Public Review): The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei Open
The actin cytoskeleton is a ubiquitous feature of eukaryotic cells, yet its complexity varies across different taxa. In the parasitic protist Trypanosoma brucei, a rudimentary actomyosin system consisting of one actin gene and two myosin g…
View article: The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei
The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei Open
The actin cytoskeleton is a ubiquitous feature of eukaryotic cells, yet its complexity varies across different taxa. In the parasitic protist Trypanosoma brucei , a rudimentary actomyosin system consisting of one actin gene and two myosin …
View article: Reviewer #3 (Public Review): The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei
Reviewer #3 (Public Review): The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei Open
The actin cytoskeleton is a ubiquitous feature of eukaryotic cells, yet its complexity varies across different taxa. In the parasitic protist Trypanosoma brucei, a rudimentary actomyosin system consisting of one actin gene and two myosin g…
View article: Reviewer #1 (Public Review): The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei
Reviewer #1 (Public Review): The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei Open
The actin cytoskeleton is a ubiquitous feature of eukaryotic cells, yet its complexity varies across different taxa. In the parasitic protist Trypanosoma brucei, a rudimentary actomyosin system consisting of one actin gene and two myosin g…
View article: The actomyosin system is essential for the integrity of the endosomal system in bloodstream form <i>Trypanosoma brucei</i>
The actomyosin system is essential for the integrity of the endosomal system in bloodstream form <i>Trypanosoma brucei</i> Open
The actin cytoskeleton is a ubiquitous feature of eukaryotic cells, yet its complexity varies across different taxa. In the parasitic protist Trypanosoma brucei , a rudimentary actomyosin system consisting of one actin gene and two myosin …
View article: Structural mechanism of outer kinetochore Dam1-Ndc80 complex assembly on microtubules
Structural mechanism of outer kinetochore Dam1-Ndc80 complex assembly on microtubules Open
Kinetochores couple chromosomes to the mitotic spindle to segregate the genome during cell division. An error correction mechanism drives the turnover of kinetochore-microtubule attachments until biorientation is achieved. The structural b…
View article: Mechanism of outer kinetochore assembly on microtubules and its regulation by mitotic error correction
Mechanism of outer kinetochore assembly on microtubules and its regulation by mitotic error correction Open
Kinetochores couple chromosomes to the mitotic spindle and transduce the energy of microtubule depolymerization to segregate the genome during cell division. Kinetochore – microtubule attachments are often initially erroneous and subject t…
View article: Actin Network Organization by the Monomeric Myosin IXa
Actin Network Organization by the Monomeric Myosin IXa Open
View article: Reconstitution Reveals How Myosin-VI Self-Organises to Generate a Dynamic Mechanism of Membrane Sculpting
Reconstitution Reveals How Myosin-VI Self-Organises to Generate a Dynamic Mechanism of Membrane Sculpting Open
View article: Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting
Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting Open
One enigma in biology is the generation, sensing and maintenance of membrane curvature. Curvature-mediating proteins have been shown to induce specific membrane shapes by direct insertion and nanoscopic scaffolding, while the cytoskeletal …
View article: The<scp>MYO</scp>6 interactome: selective motor‐cargo complexes for diverse cellular processes
The<span>MYO</span>6 interactome: selective motor‐cargo complexes for diverse cellular processes Open
Myosins of class VI ( MYO 6) are unique actin‐based motor proteins that move cargo towards the minus ends of actin filaments. As the sole myosin with this directionality, it is critically important in a number of biological processes. Inde…
View article: Self-organization of actin networks by a monomeric myosin
Self-organization of actin networks by a monomeric myosin Open
Significance Actomyosin networks are central to a broad range of cellular motile processes, including cell polarization and collective cell migration during morphogenesis and development. Myosin-IXa is critically involved in these processe…
View article: Mechanics and Activation of Unconventional Myosins
Mechanics and Activation of Unconventional Myosins Open
Many types of cellular motility are based on the myosin family of motor proteins ranging from muscle contraction to exo‐ and endocytosis, cytokinesis, cell locomotion or signal transduction in hearing. At the center of this wide range of m…
View article: Calcium can mobilize and activate myosin-VI
Calcium can mobilize and activate myosin-VI Open
Significance The timing of motor protein activation is central to a broad range of cellular motile processes including endocytosis, cell division, and cancer cell migration. The cytoskeletal motor myosin-VI is involved in these processes a…
View article: In vivo and in vitro Studies of Myosin-XXI Dynamics
In vivo and in vitro Studies of Myosin-XXI Dynamics Open
View article: Regulation of Myosin VI Studied by Electron Microscopy
Regulation of Myosin VI Studied by Electron Microscopy Open