Christopher J. Black
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View article: Prevalence of Opioid Use and Associated Healthcare Outcomes in Rome <scp>IV</scp> Irritable Bowel Syndrome in the United Kingdom
Prevalence of Opioid Use and Associated Healthcare Outcomes in Rome <span>IV</span> Irritable Bowel Syndrome in the United Kingdom Open
Background The United Kingdom (UK) has one of the highest worldwide opioid prescription rates per capita. International guidelines caution against the use of opioids for chronic non‐malignant pain, including irritable bowel syndrome (IBS).…
View article: Epidemiology of Meal‐Related Abdominal Discomfort or Pain in Irritable Bowel Syndrome
Epidemiology of Meal‐Related Abdominal Discomfort or Pain in Irritable Bowel Syndrome Open
Background Patients with IBS often report meal‐related symptoms, which may negatively affect IBS‐related quality of life, psychological health, and lead to food‐avoidant behaviors. However, the understanding of the epidemiology of these sy…
View article: Management of irritable bowel syndrome in primary care
Management of irritable bowel syndrome in primary care Open
View article: New Basic Science Editor and New Journal Management Committee Chair of Neurogastroenterology and Motility!
New Basic Science Editor and New Journal Management Committee Chair of Neurogastroenterology and Motility! Open
View article: Network Meta‐Analysis: Efficacy of Biological Therapies and Small Molecules as Maintenance Therapy in Ulcerative Colitis
Network Meta‐Analysis: Efficacy of Biological Therapies and Small Molecules as Maintenance Therapy in Ulcerative Colitis Open
Background Numerous biologics and small molecules are licensed as maintenance therapy for ulcerative colitis (UC). Differences in the design of randomised controlled trials (RCTs) have not been considered when comparing efficacy between th…
View article: Ethologically relevant behavioural assay for investigating reach and grasp kinematics during whole-body motor control in mice
Ethologically relevant behavioural assay for investigating reach and grasp kinematics during whole-body motor control in mice Open
Reach and grasp are critical components of skilled mammalian motor control and their detailed analysis in rodents has been key to deepening our understanding of prehension in the context of health and disease. However, most studies investi…
View article: Meta‐Analysis: Prevalence of Frailty and Associated Adverse Events in Inflammatory Bowel Diseases
Meta‐Analysis: Prevalence of Frailty and Associated Adverse Events in Inflammatory Bowel Diseases Open
Background The number of adults aged over 60 years with inflammatory bowel disease (IBD) is increasing. Frailty, rather than chronological age, may be a better predictor of adverse health outcomes. Aims To summarise current knowledge about…
View article: Validating Simple Modifications to the Rome <scp>IV</scp> Criteria for the Diagnosis of Irritable Bowel Syndrome in Secondary Care
Validating Simple Modifications to the Rome <span>IV</span> Criteria for the Diagnosis of Irritable Bowel Syndrome in Secondary Care Open
Background The Rome IV criteria for irritable bowel syndrome (IBS) may be too restrictive for clinical practice and research. Aims To validate the Rome IV criteria and study the diagnostic performance of simple modifications to them. Metho…
View article: And also, the basic science team of <i>Neurogastroenterology and Motility</i> gets younger!
And also, the basic science team of <i>Neurogastroenterology and Motility</i> gets younger! Open
View article: Harms with placebo in trials of biological therapies and small molecules as induction therapy in inflammatory bowel disease: a systematic review and meta-analysis
Harms with placebo in trials of biological therapies and small molecules as induction therapy in inflammatory bowel disease: a systematic review and meta-analysis Open
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View article: Novel Irritable Bowel Syndrome Subgroups Are Reproducible in the Global Adult Population
Novel Irritable Bowel Syndrome Subgroups Are Reproducible in the Global Adult Population Open
Even in the community, our original clusters derived from patients with physician-confirmed IBS identified groups of individuals with significantly higher rates of health care-seeking and abdominal surgery, more severe symptoms, and impair…
View article: Assessing Diagnostic Performance of Modifications to the Rome IV Criteria for Irritable Bowel Syndrome
Assessing Diagnostic Performance of Modifications to the Rome IV Criteria for Irritable Bowel Syndrome Open
The gold standard symptom-based criteria for diagnosis of irritable bowel syndrome (IBS) are the Rome IV criteria.1 These are more restrictive than their predecessor, Rome III, because the cardinal feature required to meet crite…
View article: Utility of irritable bowel syndrome subtypes and most troublesome symptom in predicting disease impact and burden
Utility of irritable bowel syndrome subtypes and most troublesome symptom in predicting disease impact and burden Open
Background Little is known about the characteristics of individuals with irritable bowel syndrome (IBS) according to stool subtype or the most troublesome symptom reported by the individual, or whether these are useful in predicting the im…
View article: Editorial: A Mediterranean diet for <scp>IBS</scp>—Is healthy and inclusive eating the way forward?
Editorial: A Mediterranean diet for <span>IBS</span>—Is healthy and inclusive eating the way forward? Open
LINKED CONTENT This article is linked to Staudacher et al paper. To view this article, visit https://doi.org/10.1111/apt.17791
View article: P1021 Comparison of subcutaneous and intravenous infliximab in patients with inflammatory bowel disease showed no differences in immunogenicity or treatment persistence at one year
P1021 Comparison of subcutaneous and intravenous infliximab in patients with inflammatory bowel disease showed no differences in immunogenicity or treatment persistence at one year Open
Background The effectiveness of infliximab (IFX) in inflammatory bowel disease (IBD) can be impaired by the formation of anti-drug antibodies (ADA). Subcutaneous (SC) IFX has a different pharmacokinetic profile compared to intravenous (IV)…
View article: Novel symptom clusters predict disease impact and healthcare utilisation in inflammatory bowel disease: Prospective longitudinal follow‐up study
Novel symptom clusters predict disease impact and healthcare utilisation in inflammatory bowel disease: Prospective longitudinal follow‐up study Open
Summary Background Predicting adverse disease outcomes and high‐volume users of healthcare amongst patients with inflammatory bowel disease (IBD) is difficult. Aims The aim of this study is to use latent class analysis to create novel clus…
View article: Neurogastroenterology and Motility gets younger!
Neurogastroenterology and Motility gets younger! Open
The Editors are pleased to introduce all of you to our new Trainee Editors and to invite you to read their interesting minireview on the important issue of the Lack of awareness of Neurogastroenterology and Motility within medical educatio…
View article: Efficacy of Probiotics in Irritable Bowel Syndrome: Systematic Review and Meta-analysis
Efficacy of Probiotics in Irritable Bowel Syndrome: Systematic Review and Meta-analysis Open
Some combinations of probiotics or strains may be beneficial in IBS. However, certainty in the evidence for efficacy by GRADE criteria was low to very low across almost all of our analyses.
View article: Editorial: Recognising the regional variations in profile of irritable bowel syndrome—better late than never! Authors' reply
Editorial: Recognising the regional variations in profile of irritable bowel syndrome—better late than never! Authors' reply Open
LINKED CONTENT This article is linked to Chuah et al papers. To view these articles, visit https://doi.org/10.1111/apt.17567 and https://doi.org/10.1111/apt.17620
View article: Comparison of drugs for active eosinophilic oesophagitis: systematic review and network meta-analysis
Comparison of drugs for active eosinophilic oesophagitis: systematic review and network meta-analysis Open
Background There is currently no recommendation regarding preferred drugs for active eosinophilic oesophagitis (EoE) because their relative efficacy is unclear. We conducted an up-to-date network meta-analysis to compare proton pump inhibi…
View article: Maintenance of clinical remission with biologics and small molecules in inflammatory bowel disease according to trial design: Meta-analysis
Maintenance of clinical remission with biologics and small molecules in inflammatory bowel disease according to trial design: Meta-analysis Open
Trials re-randomising patients had generally higher maintenance of remission rates, lower NNTs, and greater therapeutic gains over placebo.
View article: Letter: determining priorities for patients with faecal incontinence and irritable bowel syndrome—authors' reply
Letter: determining priorities for patients with faecal incontinence and irritable bowel syndrome—authors' reply Open
LINKED CONTENT This article is linked to Goodoory et al papers. To view these articles, visit https://doi.org/10.1111/apt.17465 and https://doi.org/10.1111/apt.17559
View article: A Diagnosis of Irritable Bowel Syndrome Using Rome IV Criteria and Limited Investigations is Durable in Secondary Care
A Diagnosis of Irritable Bowel Syndrome Using Rome IV Criteria and Limited Investigations is Durable in Secondary Care Open
Despite rereferral for gastrointestinal symptoms among 1 in 6 patients overall, with almost 10% rereferred with ongoing IBS symptoms, and substantial reinvestigation rates, missed organic gastrointestinal disease occurred in only 1%. A dia…
View article: Irritable bowel syndrome and mental health comorbidity — approach to multidisciplinary management
Irritable bowel syndrome and mental health comorbidity — approach to multidisciplinary management Open
View article: A prospective comparison of <scp>UK</scp> and Malaysian patients with irritable bowel syndrome in secondary care
A prospective comparison of <span>UK</span> and Malaysian patients with irritable bowel syndrome in secondary care Open
Summary Background The prevalence of irritable bowel syndrome (IBS) is now known to be similar in various geographical regions, but there has been no study directly comparing characteristics of patients with IBS between populations. Aims T…
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View article: Letter: Does irritable bowel syndrome have a greater impact in Western, compared with Asian, patients? Authors' reply
Letter: Does irritable bowel syndrome have a greater impact in Western, compared with Asian, patients? Authors' reply Open
LINKED CONTENT This article is linked to Goodoory et al papers. To view these articles, visit https://doi.org/10.1111/apt.17356 and https://doi.org/10.1111/apt.17485 .
View article: Editorial: faecal incontinence is prevalent in <scp>IBS</scp>, as are effective treatment options! Authors' reply
Editorial: faecal incontinence is prevalent in <span>IBS</span>, as are effective treatment options! Authors' reply Open
LINKED CONTENT This article is linked to Goodoory et al papers. To view these articles, visit https://doi.org/10.1111/apt.17465 and https://doi.org/10.1111/apt.17486 .
View article: The national prevalence of disorders of gut brain interaction in the United Kingdom in comparison to their worldwide prevalence: Results from the Rome foundation global epidemiology study
The national prevalence of disorders of gut brain interaction in the United Kingdom in comparison to their worldwide prevalence: Results from the Rome foundation global epidemiology study Open
Background There are minimal epidemiological data comparing the burden of disorders of gut brain interaction (DGBI) in the UK with other countries. We compared the prevalence of DGBI in the UK with other countries that participated in the …