Christopher Corbett
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View article: Clinical practice guidelines for the care of patients with a chronic subdural haematoma: multidisciplinary recommendations from presentation to recovery
Clinical practice guidelines for the care of patients with a chronic subdural haematoma: multidisciplinary recommendations from presentation to recovery Open
We present the first multidisciplinary guideline for the care of patients with cSDH. The recommendations reflect a paradigm shift in the care of cSDH, recognising and formalising the need for multidisciplinary and collaborative clinical ma…
View article: Protocol for the development of a multidisciplinary clinical practice guideline for the care of patients with chronic subdural haematoma
Protocol for the development of a multidisciplinary clinical practice guideline for the care of patients with chronic subdural haematoma Open
Introduction: A common neurosurgical condition, chronic subdural haematoma (cSDH) typically affects older people with other underlying health conditions. The care of this potentially vulnerable cohort is often, however, fragmented and subo…
View article: Neoadjuvant Gene-Mediated Cytotoxic Immunotherapy for Non-Small-Cell Lung Cancer: Safety and Immunologic Activity
Neoadjuvant Gene-Mediated Cytotoxic Immunotherapy for Non-Small-Cell Lung Cancer: Safety and Immunologic Activity Open
Gene-mediated cytotoxic immunotherapy (GMCI) is an immuno-oncology approach involving local delivery of a replication-deficient adenovirus expressing herpes simplex thymidine kinase (AdV-tk) followed by anti-herpetic prodrug activation tha…
View article: Evaluation of Aminolevulinic Acid-Derived Tumor Fluorescence Yields Disparate Results in Murine and Spontaneous Large Animal Models of Lung Cancer
Evaluation of Aminolevulinic Acid-Derived Tumor Fluorescence Yields Disparate Results in Murine and Spontaneous Large Animal Models of Lung Cancer Open
Fluorescence guided surgery is an emerging technology that may improve accuracy of pulmonary resection for non-small cell lung cancer (NSCLC). Herein we explore optical imaging for NSCLC surgery using the well-studied protoporphyrin IX (PP…
View article: MP25-02 INTRAOPERATIVE MOLECULAR IMAGING CAN IDENTIFY THORACIC RENAL CELL CARCINOMA METASTASES
MP25-02 INTRAOPERATIVE MOLECULAR IMAGING CAN IDENTIFY THORACIC RENAL CELL CARCINOMA METASTASES Open
You have accessJournal of UrologyKidney Cancer: Advanced (including Drug Therapy) II (MP25)1 Apr 2019MP25-02 INTRAOPERATIVE MOLECULAR IMAGING CAN IDENTIFY THORACIC RENAL CELL CARCINOMA METASTASES Christopher Corbett*, Lydia Frenzel-Sulyok,…
View article: Optimization of Second Window Indocyanine Green for Intraoperative Near-Infrared Imaging of Thoracic Malignancy
Optimization of Second Window Indocyanine Green for Intraoperative Near-Infrared Imaging of Thoracic Malignancy Open
BACKGROUND: Near-infrared (NIR) imaging using the second time window of indocyanine green (ICG) allows localization of pulmonary, pleural, and mediastinal malignancies during surgery. Based on empirical evidence, we hypothesized that diffe…
View article: First results and experience with PRRT in South Africa
First results and experience with PRRT in South Africa Open
Neuroendocrine tumors (NETs) are a diverse group of tumors that often present late due to nonspecific symptoms. These tumors frequently express somatostatin receptors (SSRs), which allows for positron emission tomography/computed tomograph…
View article: CC chemokine receptor 2 promotes recruitment of myeloid cells associated with insulin resistance in nonalcoholic fatty liver disease
CC chemokine receptor 2 promotes recruitment of myeloid cells associated with insulin resistance in nonalcoholic fatty liver disease Open
Nonalcoholic fatty liver disease (NAFLD) is a common disease, closely associated with obesity and insulin resistance. We investigated the presence of a subset of myeloid cells associated with metabolic disturbance in the liver of patients …
View article: An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas
An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas Open
This work demonstrates that FR-IMI is potentially feasible in 70% of SCC patients, and that molecular imaging can improve localization during minimally invasive pulmonary resection. These findings complement previous data demonstrating tha…
View article: Management of partial anomalous pulmonary venous connections in patients requiring pulmonary resection: a case report and systematic review
Management of partial anomalous pulmonary venous connections in patients requiring pulmonary resection: a case report and systematic review Open
Partial anomalous pulmonary venous connections (PAPVCs) are rare congenital anomalies that are frequently asymptomatic in adults. When PAPVCs are encountered in the patient requiring pulmonary resection, improper management can result in f…
View article: Granulocyte colony-stimulating factor and autologous CD133-positive stem-cell therapy in liver cirrhosis (REALISTIC): an open-label, randomised, controlled phase 2 trial
Granulocyte colony-stimulating factor and autologous CD133-positive stem-cell therapy in liver cirrhosis (REALISTIC): an open-label, randomised, controlled phase 2 trial Open
National Institute of Health Research, The Sir Jules Thorn Charitable Trust.