Christopher D. Gardner
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View article: Advances in diagnostic methods for detection of bloodstream pathogens and antibiotic resistance determinants
Advances in diagnostic methods for detection of bloodstream pathogens and antibiotic resistance determinants Open
This Perspective highlights the growing threat of multidrug-resistant bacteria in bloodstream infections and explores the role of various diagnostic technologies in the early identification of bacterial pathogens and antibiotic resistance …
View article: SAT-707 Lean Mass Loss after Dietary Weight Loss: A Secondary Analysis of the DIETFITS Randomized Clinical Trial
SAT-707 Lean Mass Loss after Dietary Weight Loss: A Secondary Analysis of the DIETFITS Randomized Clinical Trial Open
Disclosure: S. Kim: None. J. Heo: None. K. Cunanan: None. C. Gardner: None. Background: Increasing concerns have emerged regarding lean mass loss associated with GLP-1-based weight-loss medications. While a certain degree of lean mass loss…
View article: Demographic and socioeconomic factors associated with self-reported diet and physical lifestyle patterns in United States women: an NHANES study
Demographic and socioeconomic factors associated with self-reported diet and physical lifestyle patterns in United States women: an NHANES study Open
Participants who were younger than 55, non-Hispanic Black, had less than 12 years of education, low income, obese (BMI ≥ 30 kg/m2), and current smokers were more likely to report poor diet and low PA. Of obese participants, Mexican America…
View article: A human milk oligosaccharide alters the microbiome, circulating hormones, and metabolites in a randomized controlled trial of older adults
A human milk oligosaccharide alters the microbiome, circulating hormones, and metabolites in a randomized controlled trial of older adults Open
Aging-related immune dysfunction is linked to cancer, atherosclerosis, and neurodegenerative diseases. This 6-week randomized controlled trial evaluated whether 2'-fucosyllactose (2'-FL), a human breast milk oligosaccharide with establishe…
View article: Differential weight‐loss responses of <scp><i>APOA2</i></scp> genotype carriers to low‐carbohydrate and low‐fat diets: the <scp>DIETFITS</scp> trial
Differential weight‐loss responses of <span><i>APOA2</i></span> genotype carriers to low‐carbohydrate and low‐fat diets: the <span>DIETFITS</span> trial Open
Objective This study aimed to determine whether APOA2 genotypes and saturated fatty acid (SAT) intake affect weight‐loss response to healthy low‐carbohydrate (HLC) and healthy low‐fat (HLF) diets. Methods This is a secondary analysis of th…
View article: Unpacking Food Fermentation: Clinically Relevant Tools for Fermented Food Identification and Consumption
Unpacking Food Fermentation: Clinically Relevant Tools for Fermented Food Identification and Consumption Open
Fermented foods have been consumed for millennia, valued for their extended shelf life, distinctive sensory properties, and potential health benefits. Emerging research suggests that fermented food consumption may contribute to gut microbi…
View article: Reference equations for peak oxygen uptake for treadmill cardiopulmonary exercise tests based on the NHANES lean body mass equations, a FRIEND registry study
Reference equations for peak oxygen uptake for treadmill cardiopulmonary exercise tests based on the NHANES lean body mass equations, a FRIEND registry study Open
Aims Cardiorespiratory fitness (CRF), measured by peak oxygen uptake (VO2peak), is a strong predictor of mortality. Despite its widespread clinical use, current reference equations for VO2peak show distorted calibration in obese individual…
View article: A gut pathobiont regulates circulating glycine and host metabolism in a twin study comparing vegan and omnivorous diets
A gut pathobiont regulates circulating glycine and host metabolism in a twin study comparing vegan and omnivorous diets Open
Summary Metabolic diseases including type 2 diabetes and obesity pose a significant global health burden. Plant-based diets, including vegan diets, are linked to favorable metabolic outcomes, yet the underlying mechanisms remain unclear. I…
View article: A generalized equation for predicting peak oxygen consumption during treadmill exercise testing: mitigating the bias from total body mass scaling
A generalized equation for predicting peak oxygen consumption during treadmill exercise testing: mitigating the bias from total body mass scaling Open
Background Indexing peak oxygen uptake (VO 2 peak) to total body mass can underestimate cardiorespiratory fitness (CRF) in women, older adults, and individuals with obesity. The primary objective of this multicenter study was to derive and…
View article: A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites
A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites Open
β-Hydroxybutyrate (BHB) is an abundant ketone body. To date, all known pathways of BHB metabolism involve the interconversion of BHB and primary energy intermediates. Here, we identify a previously undescribed BHB secondary metabolic pathw…
View article: Longitudinal changes in lifestyle behaviours and cardiovascular health during the transition to fatherhood: the Dad Bod observational cohort study protocol
Longitudinal changes in lifestyle behaviours and cardiovascular health during the transition to fatherhood: the Dad Bod observational cohort study protocol Open
Introduction Despite the importance of the transition to fatherhood as a critical life stage among young adult men, much remains unknown about the factors predictive of ideal cardiovascular health (CVH) and how CVH is impacted as young men…
View article: Training for transformation: examining food systems courses at US land-grant universities
Training for transformation: examining food systems courses at US land-grant universities Open
Higher education institutions can play an essential role in preparing students to participate in movements for just and sustainable food systems change. For the past two decades, many United States land-grant universities (LGUs) have devel…
View article: Longitudinal Changes in Lifestyle Behaviors and Cardiovascular Health During the Transition to Fatherhood: The Dad Bod Study Rationale and Design
Longitudinal Changes in Lifestyle Behaviors and Cardiovascular Health During the Transition to Fatherhood: The Dad Bod Study Rationale and Design Open
Background Despite the importance of the transition to fatherhood as a critical life stage among young adult men, much remains unknown about the factors predictive of ideal cardiovascular health (CVH) and how CVH is impacted as young men f…
View article: Effect of Low-Carbohydrate vs Low-Fat Diet Intervention on Visceral Fat in a 12-Month Randomized Controlled Trial
Effect of Low-Carbohydrate vs Low-Fat Diet Intervention on Visceral Fat in a 12-Month Randomized Controlled Trial Open
Dietary restriction via a healthy low-fat (HLF) diet or a healthy low-carbohydrate (HLC) diet vary in their effects on adiposity and metabolism. The HLC diet, but not HLF diet, may preferentially reduce visceral adipose tissue (VAT), the m…
View article: A secondary β-hydroxybutyrate metabolic pathway linked to energy balance
A secondary β-hydroxybutyrate metabolic pathway linked to energy balance Open
Summary β-hydroxybutyrate (BHB) is an abundant ketone body. To date, all known pathways of BHB metabolism involve interconversion of BHB and primary energy intermediates. Here we show that CNDP2 controls a previously undescribed secondary …
View article: Urinary Response to Consuming Plant-Based Meat Alternatives in Persons with Normal Kidney Function
Urinary Response to Consuming Plant-Based Meat Alternatives in Persons with Normal Kidney Function Open
Key Points Eating plant-based meat versus eating animal meat is associated with lower urinary excretion of sulfate, ammonium, phosphorus, and urea nitrogen. Consuming plant-based meat compared with consuming animal meat is associated with …
View article: Unveiling the epigenetic impact of vegan vs. omnivorous diets on aging: insights from the Twins Nutrition Study (TwiNS)
Unveiling the epigenetic impact of vegan vs. omnivorous diets on aging: insights from the Twins Nutrition Study (TwiNS) Open
Background Geroscience focuses on interventions to mitigate molecular changes associated with aging. Lifestyle modifications, medications, and social factors influence the aging process, yet the complex molecular mechanisms require an in-d…
View article: Collegiate Student-Athletes’ Use and Knowledge of Third-Party-Tested Nutritional Supplements: An Exploratory Study
Collegiate Student-Athletes’ Use and Knowledge of Third-Party-Tested Nutritional Supplements: An Exploratory Study Open
Context Nutritional supplement use in athletes is common, accompanied by potential doping risk. Objective To determine athletes’ nutritional supplement and third-party-tested (TPT) supplement use, supplement knowledge, and factors influenc…
View article: The knowledge, attitudes, and perceptions towards a plant-based dietary pattern: a survey of obstetrician-gynecologists
The knowledge, attitudes, and perceptions towards a plant-based dietary pattern: a survey of obstetrician-gynecologists Open
Background Obstetricians-gynecologists (OB/GYNs) play a critical role for their pregnant patients during their perinatal period, but research on OB/GYNs knowledge, attitudes, and perceptions regarding plant-based dietary patterns (PBDP) an…
View article: Diet Quality and Resilience through Adulthood: A Cross-Sectional Analysis of the WELL for Life Study
Diet Quality and Resilience through Adulthood: A Cross-Sectional Analysis of the WELL for Life Study Open
Despite evidence suggesting the importance of psychological resilience for successful aging, little is known about the relationship between diet quality and resilience at different ages. Our study aims to examine the association between di…
View article: Development of a screener to assess athlete risk behavior of not using third-party tested nutritional supplements
Development of a screener to assess athlete risk behavior of not using third-party tested nutritional supplements Open
Introduction The aim of this cross-sectional study was to develop an algorithm to predict athletes use of third-party tested (TPT) supplements. Therefore, a nutritional supplement questionnaire was used with a section about self-reported T…
View article: Cardiovascular health and cancer risk associated with plant based diets: An umbrella review
Cardiovascular health and cancer risk associated with plant based diets: An umbrella review Open
Context Cardiovascular diseases (CVDs) and cancer are the two main leading causes of death and disability worldwide. Suboptimal diet, poor in vegetables, fruits, legumes and whole grain, and rich in processed and red meat, refined grains, …
View article: Regarding: the impacts of partial replacement of red and processed meat with legumes or cereals on protein and amino acid intakes: a modelling study in the Finnish adult population
Regarding: the impacts of partial replacement of red and processed meat with legumes or cereals on protein and amino acid intakes: a modelling study in the Finnish adult population Open
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