Christopher Dodt
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The essential co-chaperone Sgt1 regulates client dwell time in the Hsp90 chaperone cycle Open
The Hsp90 molecular chaperone system is regulated by numerous co-chaperones that modulate its function. In Saccharomyces cerevisiae, most of these cofactors can be deleted without affecting viability. Of the three essential ones, only the …
View article: The essential co-chaperone Sgt1 regulates client dwell time in the Hsp90 chaperone cycle
The essential co-chaperone Sgt1 regulates client dwell time in the Hsp90 chaperone cycle Open
SUMMARY The Hsp90 machinery is the most complex chaperone system in the eukaryotic cell. It is characterized by numerous co-chaperones that modulate the function of Hsp90. In S. cerevisiae , most of these cofactors can be deleted without a…