Christopher E. Monti
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The effective multiplicity of infection for HCMV depends on the activity of the cellular 20S proteasome Open
Human cytomegalovirus (HCMV) is a betaherpesvirus capable of infecting numerous cell types and persisting throughout an infected individual’s life. Disease usually occurs in individuals with compromised or underdeveloped immune systems. Se…
The effective multiplicity of infection for HCMV depends on activity of the cellular 20S proteasome Open
Human cytomegalovirus (HCMV) is a betaherpesvirus capable of infecting numerous cell types and persisting throughout an infected individual’s life. Disease usually occurs in individuals with compromised or underdeveloped immune systems. Se…
Replication efficiencies of human cytomegalovirus-infected epithelial cells are dependent on source of virus production Open
Human cytomegalovirus (HCMV) is a prevalent betaherpesvirus, and infection can lead to a range of symptomatology from mononucleosis to sepsis in immunocompromised individuals. HCMV is also the leading viral cause of congenital birth defect…
Computational modeling of protracted HCMV replication using genome substrates and protein temporal profiles Open
Human cytomegalovirus (HCMV) is a major cause of illness in immunocompromised individuals. The HCMV lytic cycle contributes to the clinical manifestations of infection. The lytic cycle occurs over ∼96 h in diverse cell types and consists o…