Christopher K. Senkowski
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View article: Obesity, Race, and COVID-19 Mortality: Results from a Large Cohort Early in the Pandemic
Obesity, Race, and COVID-19 Mortality: Results from a Large Cohort Early in the Pandemic Open
COVID-19 mortality was significantly related to BMI, age and select co-morbidities, but race/ethnicity was not a predictor of mortality when controlling for other variables.
View article: The Spectrum of Large Adrenal Masses: A Case Series
The Spectrum of Large Adrenal Masses: A Case Series Open
Although adrenocortical carcinoma is an uncommon cancer, it has significant implications for the patient's prognosis and ultimately, their treatment algorithm. Therefore, when evaluating large adrenal masses, surgeons must remain vigilant …
View article: Large mediastinal haematoma after paraoesophageal hernia repair
Large mediastinal haematoma after paraoesophageal hernia repair Open
Mediastinal haematoma is a rare complication of laparoscopic paraoesophageal hernia repair with few documented cases in the current literature. Presentation of this unique clinical problem can range from extrinsic oesophageal obstruction t…
View article: Recombinant HE4 protein promotes proliferation of pancreatic and endometrial cancer cell lines
Recombinant HE4 protein promotes proliferation of pancreatic and endometrial cancer cell lines Open
Pancreatic adenocarcinoma is one of the most deadly malignancies, and endometrial cancer represents the most common gynecologic cancer in the USA. Better understanding on the pathologic mechanisms and pathways is required for effective tre…
View article: Promoter Hypermethylation and Decreased Expression of Syncytin-1 in Pancreatic Adenocarcinomas
Promoter Hypermethylation and Decreased Expression of Syncytin-1 in Pancreatic Adenocarcinomas Open
Syncytin-1 is a member of human endogenous retroviral W gene family (HERVW1). Known to be expressed in human placental trophoblast, syncytin-1 protein mediates the fusion of cytotrophoblasts for the formation of syncytiotrophoblasts, the t…
View article: Expression and Diagnostic Value of HE4 in Pancreatic Adenocarcinoma
Expression and Diagnostic Value of HE4 in Pancreatic Adenocarcinoma Open
Human epididymis protein 4 (HE4) is a recognized biomarker in ovarian and endometrial cancer and over-expressed in pancreatic adenocarcinoma. The diagnostic value of HE4 in pancreatic adenocarcinoma remains unknown. Here we elucidate mRNA,…