Christopher M. Lemon
YOU?
Author Swipe
View article: Hangman dipyrrin complexes
Hangman dipyrrin complexes Open
We have developed hangman dipyrrin complexes with secondary sphere residues that perform proton transfer and bind small molecules. Atropisomerism confers rigidity, mimicking the stable positioning of amino acid side chains in protein activ…
View article: Hangman Dipyrrin Complexes
Hangman Dipyrrin Complexes Open
Mononuclear copper enzymes, such as polysaccharide monooxygenase (PMO) and particulate methane monooxygenase (pMMO), serve as inspiration for novel molecular catalysts and model systems. While chemists have designed complexes that mimic th…
View article: Beyond BODIPY: dipyrrin complexes of P-block elements
Beyond BODIPY: dipyrrin complexes of P-block elements Open
Dipyrrin has proven to be a versatile ligand platform for metals across the periodic table. Since much of the coordination chemistry has focused on transition metals, main-group dipyrrin chemistry has been underexplored, particularly in th…
View article: CCDC 2180997: Experimental Crystal Structure Determination
CCDC 2180997: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1046909: Experimental Crystal Structure Determination
CCDC 1046909: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Simulation data for "Corrole-protein interactions in H-Nox and HasA"
Simulation data for "Corrole-protein interactions in H-Nox and HasA" Open
Molecular dynamics simulation trajectories, metadata, and analysis script for the manuscript "Corrode-Protein interactions in H-Nox and HasA" (article link) by Christopher M. Lemon, Amos J. Nissley, Naomi R. Latorraca, Elizabeth C. Wittenb…
View article: Simulation data for "Corrole-protein interactions in H-Nox and HasA"
Simulation data for "Corrole-protein interactions in H-Nox and HasA" Open
Molecular dynamics simulation trajectories, metadata, and analysis script for the manuscript "Corrode-Protein interactions in H-Nox and HasA" (article link) by Christopher M. Lemon, Amos J. Nissley, Naomi R. Latorraca, Elizabeth C. Wittenb…
View article: Corrole–protein interactions in H-NOX and HasA
Corrole–protein interactions in H-NOX and HasA Open
Mutagenesis was utilised to reveal corrole–protein interactions in H-NOX and HasA. The key interaction is a hydrogen bond between the PO unit of the corrole and a protonated histidine residue.
View article: Designer Heme Proteins: Achieving Novel Function with Abiological Heme Analogues
Designer Heme Proteins: Achieving Novel Function with Abiological Heme Analogues Open
Heme proteins have proven to be a convenient platform for the development of designer proteins with novel functionalities. This is achieved by substituting the native iron porphyrin cofactor with a heme analogue that possesses the desired …
View article: Corrole-Substituted Fluorescent Heme Proteins
Corrole-Substituted Fluorescent Heme Proteins Open
Although fluorescent proteins have been utilized for a variety of biological applications, they have several optical limitations, namely weak red and near-infrared emission and exceptionally broad (>200 nm) emission profiles. The photophys…
View article: A constrained pressure-temperature residual (CPTR) method for\n non-isothermal multiphase flow in porous media
A constrained pressure-temperature residual (CPTR) method for\n non-isothermal multiphase flow in porous media Open
For both isothermal and thermal petroleum reservoir simulation, the\nConstrained Pressure Residual (CPR) method is the industry-standard\npreconditioner. This method is a two-stage process involving the solution of a\nrestricted pressure s…
View article: Optical oxygen sensing with quantum dot conjugates
Optical oxygen sensing with quantum dot conjugates Open
The ability to track and quantify changes in oxygen concentration as a function of disease progression or therapy is crucial to advance targeted chemotherapeutics. New non-invasive sensors must be developed that are small enough to penetra…
View article: Halogen Photoelimination from Sb<sup>V</sup> Dihalide Corroles
Halogen Photoelimination from Sb<sup>V</sup> Dihalide Corroles Open
Main-group p-block metals are ideally suited for mediating two-electron reactions because they cycle between M n and M n+2 redox states, as the one-electron state is thermodynamically unstable. Here, we report the synthesis and structure o…
View article: CCDC 1049494: Experimental Crystal Structure Determination
CCDC 1049494: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1555261: Experimental Crystal Structure Determination
CCDC 1555261: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Gold Corroles as Near-IR Phosphors for Oxygen Sensing
Gold Corroles as Near-IR Phosphors for Oxygen Sensing Open
The triplet state of gold(III) corroles is exploited for optical oxygen sensing. We report intense phosphorescence for gold(III) corroles in the near-IR, an optical window that is ideal for tissue transparency. Moreover, the triplet excite…
View article: CCDC 993647: Experimental Crystal Structure Determination
CCDC 993647: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Donor-Acceptor Constructs for Optical Oxygen Sensing and Corroles: Photophysics, Electronic Structure, and Photochemistry
Donor-Acceptor Constructs for Optical Oxygen Sensing and Corroles: Photophysics, Electronic Structure, and Photochemistry Open
Metabolic tumor profiling illustrates the spatiotemporal distribution of key analytes to assess and quantify tumor growth, metabolism, and response to therapy. Since the tumor microenvironment is characterized by hypoxia, the ability to tr…
View article: CCDC 1046908: Experimental Crystal Structure Determination
CCDC 1046908: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1464435: Experimental Crystal Structure Determination
CCDC 1464435: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as <i>in Vivo</i> Two-Photon Oxygen Sensors
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as <i>in Vivo</i> Two-Photon Oxygen Sensors Open
Micelles have been employed to encapsulate the supramolecular assembly of quantum dots with palladium(II) porphyrins for the quantification of O2 levels in aqueous media and in vivo. Förster resonance energy transfer from the quantum dot (…
View article: Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as Open
Micelles have been employed to encapsulate the supramolecular assembly of quantum dots with palladium(II) porphyrins for the quantification of O₂ levels in aqueous media and in vivo. Förster resonance energy transfer from the quantum dot (…
View article: CCDC 1056646: Experimental Crystal Structure Determination
CCDC 1056646: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1056647: Experimental Crystal Structure Determination
CCDC 1056647: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1056645: Experimental Crystal Structure Determination
CCDC 1056645: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …