Christopher Leonardi
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View article: A Critical Review of Critical Factors Influencing Airborne Particle Transmission in Indoor Environments Under Stationary and Dynamic Scenarios
A Critical Review of Critical Factors Influencing Airborne Particle Transmission in Indoor Environments Under Stationary and Dynamic Scenarios Open
Understanding the spread of airborne viruses in indoor environments is a complex challenge due to the interplay of physical, environmental, and chemical factors. While numerous studies have specified elements such as human movement, ventil…
View article: Measuring implicit line orientation discrimination using fast periodic visual stimulation
Measuring implicit line orientation discrimination using fast periodic visual stimulation Open
The fast periodic visual stimulation oddball paradigm (FPVS-oddball) is an electroencephalography (EEG) marker of discrimination between two classes of frequency tagged stimuli (standards and oddballs). Here, we probe low-level visual func…
View article: Application of a Phenotype-Based Predictive Analytic in a Phase Ib Study of Selinexor and Venetoclax in Patients with Relapsed or Refractory Acute Myeloid Leukemia
Application of a Phenotype-Based Predictive Analytic in a Phase Ib Study of Selinexor and Venetoclax in Patients with Relapsed or Refractory Acute Myeloid Leukemia Open
Introduction Selective inhibitor of nuclear export (SINE) compounds block XPO1/elF4E-mediated nuclear-cytoplasmic transport, and lead to nuclear retention and activation of tumor suppressor proteins (e.g., p53) and impaired translation of …
View article: PEARL-SCALLOP: Parameter Extension Applicable in Real Life for SCALLOP
PEARL-SCALLOP: Parameter Extension Applicable in Real Life for SCALLOP Open
A crucial ingredient for many cryptographic primitives such as key exchange protocols and advanced signature schemes is a commutative group action where the structure of the underlying group can be computed efficiently. SCALLOP provides su…
View article: Measuring implicit line orientation discrimination using fast periodic visual stimulation
Measuring implicit line orientation discrimination using fast periodic visual stimulation Open
Fast periodic visual stimulation (FPVS) is an electroencephalography (EEG) marker of discrimination between two classes of frequency tagged stimuli (standards and oddballs). Here, we develop FPVS as a probe of low-level visual function, wi…
View article: Proppant transport at the intersection of coal cleats and hydraulic fractures
Proppant transport at the intersection of coal cleats and hydraulic fractures Open
This work is the first computational study of proppant leak-off through coal cleats that accounts for proppant retention in cleats, occlusion formation at cleat entrances, the resulting control of fluid leak-off, and the influence of reali…
View article: Hydrodynamics of molten media bubble columns for hydrogen production through methane pyrolysis
Hydrodynamics of molten media bubble columns for hydrogen production through methane pyrolysis Open
Methane pyrolysis using a molten media bubble column reactor is a promising technique for hydrogen production with low carbon dioxide emissions at a feasible price. Understanding the bubble dynamics in molten media is essential to elucidat…
View article: Computational investigation of the role of ventricular remodelling in HFpEF: The key to phenotype dissection
Computational investigation of the role of ventricular remodelling in HFpEF: The key to phenotype dissection Open
Recent clinical studies have reported that heart failure with preserved ejection fraction (HFpEF) can be divided into two phenotypes based on the range of ejection fraction (EF), namely HFpEF with higher EF and HFpEF with lower EF. These p…
View article: Contextual existence of an optimum through-plane orientation and aspect ratio of a fiber-segment in fibrous air filters
Contextual existence of an optimum through-plane orientation and aspect ratio of a fiber-segment in fibrous air filters Open
Fibrous air filters have emerged extensively as a remedial indoor solution to address severe air pollution. To understand the complexities involved in variation of their performance with respect to their fiber anisotropy, a fundamental num…
View article: Development of a central-moment phase-field lattice Boltzmann model for thermocapillary flows: Droplet capture and computational performance
Development of a central-moment phase-field lattice Boltzmann model for thermocapillary flows: Droplet capture and computational performance Open
This study develops a computationally efficient phase-field lattice Boltzmann model with the capability to simulate thermocapillary flows. The model was implemented into the open-source simulation framework, waLBerla, and extended to condu…
View article: Comprehensive Computational Study on the Influences of Particle Size and Relative Humidity on Aerosol/Droplet Transmission in a Ventilated Room Under Stationary and Dynamic Conditions
Comprehensive Computational Study on the Influences of Particle Size and Relative Humidity on Aerosol/Droplet Transmission in a Ventilated Room Under Stationary and Dynamic Conditions Open
Given the concerns surrounding the possibility of crosscontamination caused by the airborne transmission of respiratory aerosols (> 5 μ m in diameter) and droplets (> 5 μ m in diameter) containing infectious viruses, there is a great need …
View article: Numerical investigation of the effect of nanoparticle aggregation on the performance of concentrated photovoltaic-solar thermal collectors with spectral filtering
Numerical investigation of the effect of nanoparticle aggregation on the performance of concentrated photovoltaic-solar thermal collectors with spectral filtering Open
Solar energy, particularly solar thermal technology, has gained popularity as a possible long-term replacement to fossil fuels. The application of concentrated photovoltaic-solar thermal (CPV/T) collectors, which are improved by spectral f…
View article: Assessment of capillary rise in rocks by Time Lapse Digital Imaging
Assessment of capillary rise in rocks by Time Lapse Digital Imaging Open
Solution flow can significantly influence metal recovery and kinetics in leaching, especially in heap/dump/In-situ leaching, however, the vast majority of the work in this area has focused on the inter-particle fluid flow, and only a few s…
View article: An experimental investigation of the fluid accessibility of preconditioned sulphide copper ores
An experimental investigation of the fluid accessibility of preconditioned sulphide copper ores Open
Copper is crucial for a transition to a low-carbon economy and for energy-efficient technologies. In nature, can be mostly found in minerals as combination with iron and sulphide and its conversion into pure copper metal is frequently prod…
View article: Hydrodynamic clogging of micro-particles in planar channels under electrostatic forces
Hydrodynamic clogging of micro-particles in planar channels under electrostatic forces Open
Hydrodynamic clogging in planar channels is studied via direct numerical simulation for the first time, utilising a novel numerical test cell and stochastic methodology with special focus on the influence of electrostatic forces. Electrost…
View article: Quantifying the Permeability Enhancement from Blast-Induced Microfractures in Porphyry Rocks Using a Cumulant Lattice Boltzmann Method
Quantifying the Permeability Enhancement from Blast-Induced Microfractures in Porphyry Rocks Using a Cumulant Lattice Boltzmann Method Open
The permeability of rocks is important in a range of geoscientific applications, including $$\hbox {CO}_{2}$$ sequestration, geothermal energy extraction, and in situ mineral recovery. This work presents an investigation of the change …